Human Intestinal Transporter Database: QSAR Modeling and Virtual Profiling of Drug Uptake, Efflux and Interactions

ABC Multidrug Transporters: Target for Modulation of Drug Pharmacokinetics and Drug-Drug Interactions

(2011) Beatrice Marquez et al.   CURRENT DRUG TARGETS

A Novel Approach for Predicting P-Glycoprotein (ABCB1) Inhibition Using Molecular Interaction Fields

(2011) Fabio Broccatelli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure–activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP)

(2010) Anne Pick et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Trust, But Verify: On the Importance of Chemical Structure Curation in Cheminformatics and QSAR Modeling Research

(2010) Denis Fourches et al.   Journal of Chemical Information and Modeling

Molecular Switch Controlling the Binding of Anionic Bile Acid Conjugates to Human Apical Sodium-Dependent Bile Acid Transporter

(2010) Rana Rais et al.   JOURNAL OF MEDICINAL CHEMISTRY

Best Practices for QSAR Model Development, Validation, and Exploitation

(2010) Alexander Tropsha   Molecular Informatics

Understanding transport through pharmacological barriers — are we there yet?

(2010) Balázs Sarkadi et al.   NATURE REVIEWS DRUG DISCOVERY

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs

(2010) C. Knox et al.   NUCLEIC ACIDS RESEARCH

Pharmacogenomics of membrane transporters: past, present and future

(2010) Sook Wah Yee et al.   PHARMACOGENOMICS

Structure–Activity Relationships and Quantitative Structure–Activity Relationships for Breast Cancer Resistance Protein (ABCG2)

(2009) Yash A. Gandhi et al.   AAPS Journal

Role of basolateral efflux transporter MRP4 in the intestinal absorption of the antiviral drug adefovir dipivoxil

(2009) Xin Ming et al.   BIOCHEMICAL PHARMACOLOGY

Development of Decision Tree Models for Substrates, Inhibitors, and Inducers of P-Glycoprotein

(2009) Felix Hammann et al.   CURRENT DRUG METABOLISM

Computational Models for Drug Inhibition of the Human Apical Sodium-Dependent Bile Acid Transporter

(2009) Xiaowan Zheng et al.   MOLECULAR PHARMACEUTICS

The Role of Transporters in the Pharmacokinetics of Orally Administered Drugs

(2009) Sarah Shugarts et al.   PHARMACEUTICAL RESEARCH

Identification of Novel Specific and General Inhibitors of the Three Major Human ATP-Binding Cassette Transporters P-gp, BCRP and MRP2 Among Registered Drugs

(2009) Pär Matsson et al.   PHARMACEUTICAL RESEARCH

Permeability – In Vitro Assays for Assessing Drug Transporter Activity

(2008) Hong Jin et al.   CURRENT DRUG METABOLISM

Support vector machine and pharmacophore-based prediction models of multidrug-resistance protein 2 (MRP2) inhibitors

(2008) Hui Zhang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Structural Requirements for Drug Inhibition of the Liver Specific Human Organic Cation Transport Protein 1

(2008) Gustav Ahlin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Prediction and Identification of Drug Interactions with the Human ATP-Binding Cassette Transporter Multidrug-Resistance Associated Protein 2 (MRP2; ABCC2)

(2008) Jenny M. Pedersen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pharmacophore mapping of a series of pyrrolopyrimidines, indolopyrimidines and their congeners as multidrug-resistance-associated protein (MRP1) modulators

(2008) Nilesh R. Tawari et al.   JOURNAL OF MOLECULAR MODELING

The Transporter Classification Database: recent advances

(2008) M. H. Saier et al.   NUCLEIC ACIDS RESEARCH

QSAR Models for the Human H+/Peptide Symporter, hPEPT1:  Affinity Prediction Using Alignment-Independent Descriptors

(2007) Simon Birksø Larsen et al.   Journal of Chemical Information and Modeling