Translating cellular therapies from bench to bedside for amyotrophic lateral sclerosis

Olfactory Ensheathing Cell Neurorestorotherapy for Amyotrophic Lateral Sclerosis Patients: Benefits from Multiple Transplantations

(2012) Lin Chen et al.   CELL TRANSPLANTATION

Intraspinal Stem Cell Transplantation in Amyotrophic Lateral Sclerosis

(2012) Jonathan Riley et al.   NEUROSURGERY

Neurotrophic Bone Marrow Cellular Nests Prevent Spinal Motoneuron Degeneration in Amyotrophic Lateral Sclerosis Patients: A Pilot Safety Study

(2012) Miguel Blanquer et al.   STEM CELLS

Lumbar Intraspinal Injection of Neural Stem Cells in Patients with Amyotrophic Lateral Sclerosis: Results of a Phase I Trial in 12 Patients

(2012) Jonathan D. Glass et al.   STEM CELLS

Mesenchymal stromal cell transplantation in amyotrophic lateral sclerosis: a long-term safety study

(2011) Letizia Mazzini et al.   CYTOTHERAPY

Current hypotheses for the underlying biology of amyotrophic lateral sclerosis

(2010) Jeffrey D. Rothstein   ANNALS OF NEUROLOGY

Analysis of Dosing Regimen and Reproducibility of Intraspinal Grafting of Human Spinal Stem Cells in Immunosuppressed Minipigs

(2010) Dusan Usvald et al.   CELL TRANSPLANTATION

In vitro and in vivo characterization of tapentadol metabolites

(2010) R. Terlinden et al.   METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY

Cervical Multilevel Intraspinal Stem Cell Therapy

(2010) Bethwel Raore et al.   SPINE

Neuropathology of Olfactory Ensheathing Cell Transplantation into the Brain of Two Amyotrophic Lateral Sclerosis (ALS) Patients

(2009) Maria Teresa Giordana et al.   BRAIN PATHOLOGY

Growth factor-expressing human neural progenitor cell grafts protect motor neurons but do not ameliorate motor performance and survival in ALS mice

(2009) Sungju Park et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Mesenchymal stem cell transplantation in amyotrophic lateral sclerosis: A Phase I clinical trial

(2009) L. Mazzini et al.   EXPERIMENTAL NEUROLOGY

Extracellular mutant SOD1 induces microglial-mediated motoneuron injury

(2009) Weihua Zhao et al.   GLIA

Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

(2009) Hristelina Ilieva et al.   JOURNAL OF CELL BIOLOGY

Human neural stem cell grafts in the spinal cord of SOD1 transgenic rats: Differentiation and structural integration into the segmental motor circuitry

(2009) Leyan Xu et al.   JOURNAL OF COMPARATIVE NEUROLOGY

A Switch in Retrograde Signaling from Survival to Stress in Rapid-Onset Neurodegeneration

(2009) E. Perlson et al.   JOURNAL OF NEUROSCIENCE

Chimerization of astroglial population in the lumbar spinal cord after mesenchymal stem cell transplantation prolongs survival in a rat model of amyotrophic lateral sclerosis

(2009) Cédric Boucherie et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Presynaptic Regulation of Astroglial Excitatory Neurotransmitter Transporter GLT1

(2009) Yongjie Yang et al.   NEURON

CERVICAL SPINAL CORD THERAPEUTICS DELIVERY

(2009) Jonathan Riley et al.   NEUROSURGERY

Treatment of amyotrophic lateral sclerosis patients by autologous bone marrow-derived hematopoietic stem cell transplantation: a 1-year follow-up

(2008) H. Deda et al.   CYTOTHERAPY

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1

(2008) H. Nishitoh et al.   GENES & DEVELOPMENT

Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis†

(2008) Cristina Cheroni et al.   HUMAN MOLECULAR GENETICS

Focal transplantation–based astrocyte replacement is neuroprotective in a model of motor neuron disease

(2008) Angelo C Lepore et al.   NATURE NEUROSCIENCE

Human mesenchymal stem cell transplantation extends survival, improves motor performance and decreases neuroinflammation in mouse model of amyotrophic lateral sclerosis

(2008) A. Vercelli et al.   NEUROBIOLOGY OF DISEASE

Selective association of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria

(2008) C. Vande Velde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stem cell treatment in Amyotrophic Lateral Sclerosis

(2007) Letizia Mazzini et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES