A literature review on the representativeness of randomized controlled trial samples and implications for the external validity of trial results
出版年份 2015 全文链接
标题
A literature review on the representativeness of randomized controlled trial samples and implications for the external validity of trial results
作者
关键词
Randomized controlled trial, External validity, Generalizability, Real-world patients, Cardiology, Mental health, Oncology, Literature review
出版物
Trials
Volume 16, Issue 1, Pages -
出版商
Springer Nature
发表日期
2015-11-04
DOI
10.1186/s13063-015-1023-4
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- The PRECIS-2 tool: designing trials that are fit for purpose
- (2015) K. Loudon et al. BMJ-British Medical Journal
- The PRECIS-2 tool: designing trials that are fit for purpose
- (2015) K. Loudon et al. BMJ-British Medical Journal
- A Primer on Effectiveness and Efficacy Trials
- (2014) Amit G Singal et al. Clinical and Translational Gastroenterology
- Comparison of treatment outcome in metastatic colorectal cancer patients included in a clinical trial versus daily practice in The Netherlands
- (2013) Linda Mol et al. ACTA ONCOLOGICA
- CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomized Trials
- (2013) Kenneth F. Schulz ANNALS OF INTERNAL MEDICINE
- Generalizability of Clinical Trial Results for Bipolar Disorder to Community Samples
- (2013) Nicolas Hoertel et al. JOURNAL OF CLINICAL PSYCHIATRY
- The Necessity for Clinical Reasoning in the Era of Evidence-Based Medicine
- (2013) Allan D. Sniderman et al. MAYO CLINIC PROCEEDINGS
- The use of propensity scores and observational data to estimate randomized controlled trial generalizability bias
- (2013) Taylor R. Pressler et al. STATISTICS IN MEDICINE
- Acute Heart Failure
- (2012) Justin A. Ezekowitz et al. Circulation-Heart Failure
- Eligibility criteria in randomized phase II and III adjuvant and neoadjuvant breast cancer trials: Not a significant barrier to enrollment
- (2012) Myriam Filion et al. Clinical Trials
- External validity of randomized controlled trials of glycaemic control and vascular disease: how representative are participants?
- (2012) C. Saunders et al. DIABETIC MEDICINE
- Characteristics of Advanced Cancer Patients With Cancer-Related Fatigue Enrolled in Clinical Trials and Patients Referred to Outpatient Palliative Care Clinics
- (2012) Sriram Yennurajalingam et al. JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
- The older the better: are elderly study participants more non-representative? A cross-sectional analysis of clinical trial and observational study samples
- (2012) Beatrice A Golomb et al. BMJ Open
- The eligibility of advanced non-small-cell lung cancer patients for targeted therapy clinical trials
- (2011) J. Clarey et al. ANNALS OF ONCOLOGY
- Differences Between Clinical Trial Participants and Patients in a Population-Based Registry
- (2011) Paul Kalata et al. DISEASES OF THE COLON & RECTUM
- Comparison of Baseline Characteristics, Management and Outcome of Patients With Non–ST-Segment Elevation Acute Coronary Syndrome in Versus Not in Clinical Trials
- (2010) Adam B. Hutchinson-Jaffe et al. AMERICAN JOURNAL OF CARDIOLOGY
- Are patients with Hodgkin lymphoma and high-grade non-Hodgkin lymphoma in clinical therapy optimization protocols representative of these groups of patients in Germany?
- (2010) C. Terschuren et al. ANNALS OF ONCOLOGY
- Representation of Women in Randomized Clinical Trials of Cardiovascular Disease Prevention
- (2010) Chiara Melloni et al.
- The generalizability of participants in Veterans Affairs Cooperative Studies Program 474, a multi-site randomized cardiac bypass surgery trial
- (2010) Todd H. Wagner et al. Contemporary Clinical Trials
- Observational studies: going beyond the boundaries of randomized controlled trials
- (2010) Wenying Yang et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Are patients in clinical trials representative of the general population? Dose intensity and toxicities associated with FE100C-D chemotherapy in a non-trial population of node positive breast cancer patients compared with PACS-01 trial group
- (2010) Judith Fraser et al. EUROPEAN JOURNAL OF CANCER
- Do Efficacy and Effectiveness Samples Differ in Antidepressant Treatment Outcome?
- (2010) Florian Seemüller et al. JOURNAL OF CLINICAL PSYCHIATRY
- Representativeness of Participants in a Clinical Trial for Attention-Deficit/Hyperactivity Disorder?
- (2010) Craig B. H. Surman et al. JOURNAL OF CLINICAL PSYCHIATRY
- The use of propensity scores to assess the generalizability of results from randomized trials
- (2010) Elizabeth A. Stuart et al. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY
- Trials Assessing Parmacotherapeutic Management of Aggression in Psychiatric Patients: Comparability with Clinical Practice
- (2010) L. E. Goedhard et al. PHARMACOPSYCHIATRY
- The generalizability of antidepressant efficacy trials to routine psychiatric out-patient practice
- (2010) R. van der Lem et al. PSYCHOLOGICAL MEDICINE
- Clinical Benefit of Early Reperfusion Therapy in Patients With ST-Elevation Myocardial Infarction Usually Excluded from Randomized Clinical Trials (Results from the Maximal Individual Therapy in Acute Myocardial Infarction Plus [MITRA Plus] Registry)
- (2009) Oliver Koeth et al. AMERICAN JOURNAL OF CARDIOLOGY
- From Randomized Controlled Trials to Observational Studies
- (2009) Stuart L. Silverman AMERICAN JOURNAL OF MEDICINE
- Can Phase III Trial Results of Antidepressant Medications Be Generalized to Clinical Practice? A STAR*D Report
- (2009) Stephen R. Wisniewski et al. AMERICAN JOURNAL OF PSYCHIATRY
- Eligibility of patients with advanced non-small cell lung cancer for phase III chemotherapy trials
- (2009) Janette Vardy et al. BMC CANCER
- A comparison of depressed patients in randomized versus nonrandomized trials of antidepressant medication and psychotherapy
- (2009) Shauna C. Kushner et al. DEPRESSION AND ANXIETY
- Generalizability of Clinical Trial Results for Major Depression to Community Samples
- (2009) Carlos Blanco et al. JOURNAL OF CLINICAL PSYCHIATRY
- Patients Enrolled in Large Randomized Clinical Trials of Antiplatelet Treatment for Prevention After Transient Ischemic Attack or Ischemic Stroke Are Not Representative of Patients in Clinical Practice
- (2009) Lisette Maasland et al. STROKE
- Variations Between Clinical Trial Participants and Medicare Beneficiaries in Evidence Used for Medicare National Coverage Decisions
- (2008) Sanket S. Dhruva ARCHIVES OF INTERNAL MEDICINE
- Assessment of unmet needs and the lack of generalizability in the design of randomized controlled trials for scleroderma treatment
- (2008) Renata Villela et al. ARTHRITIS AND RHEUMATISM
- Beyond the Randomized Clinical Trial
- (2008) Brahmajee K. Nallamothu et al. CIRCULATION
- Restrictive Eligibility Limits Access to Newer Therapies in Non–Small-Cell Lung Cancer: The Implications of Eastern Cooperative Oncology Group 4599
- (2008) Robert A. Somer et al. Clinical Lung Cancer
- Comparison of mania patients suitable for treatment trials versus clinical treatment
- (2008) Alessandra Talamo et al. HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
- Eligibility criteria in heart failure randomized controlled trials: a gap between evidence and clinical practice
- (2008) Giorgio Costantino et al. Internal and Emergency Medicine
- Causes of ineligibility in randomized controlled trials and long-term mortality in patients with non-ST-segment elevation acute coronary syndromes
- (2007) Xavier Bosch et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Recent developments in meta-analysis
- (2007) Alexander J. Sutton et al. STATISTICS IN MEDICINE
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started