Article
Public, Environmental & Occupational Health
Ming-Jen Tsai, Cheng-Han Tsai, Ru-Chiou Pan, Chi-Feng Hsu, Sheng-Feng Sung
Summary: This study developed and validated case definition algorithms for out-of-hospital cardiac arrest (OHCA) based on ICD diagnostic codes and billing codes for NHI reimbursement, providing an important reference for future OHCA studies using the Taiwan NHI database.
CLINICAL EPIDEMIOLOGY
(2022)
Article
Obstetrics & Gynecology
Amy Metcalfe, Manal Sheikh, Erin Hetherington
Summary: This study evaluated the impact of transition from the International Classification of Diseases, Ninth Revision, to the Tenth Revision coding systems on severe maternal morbidity incidence in US hospital discharge data. The results showed a significant decrease in severe maternal morbidity incidence following the transition, indicating a sudden and clinically meaningful change associated with the coding shift.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Article
Family Studies
Kathleen A. Noorbakhsh, Rachel P. Berger, Sriram Ramgopal
Summary: This study evaluated the validity of converting ICD-9-CM diagnosis codes to the 10th revision for identifying child maltreatment. The results showed that the current conversion methods are not consistently reliable, highlighting the need for independent construction and validation of ICD-10-based definitions of child maltreatment.
CHILD ABUSE & NEGLECT
(2022)
Article
Substance Abuse
Christopher L. Rowe, Glenn-Milo Santos, Wiley Kornbluh, Sumeet Bhardwaj, Mark Faul, Phillip O. Coffin
Summary: ICD-10-CM codes had low sensitivity but high specificity for detecting self-reported substance use. They were more sensitive in detecting frequent use, especially among outpatient visits.
DRUG AND ALCOHOL DEPENDENCE
(2021)
Article
Oncology
Sheila Weinmann, Melanie C. Francisco, Marilyn L. Kwan, Erin J. A. Bowles, Alanna Kulchak Rahm, Robert T. Greenlee, Natasha K. Stout, Jason D. Pole, Lawrence H. Kushi, Rebecca Smith-Bindman, Diana L. Miglioretti
Summary: The study found that using diagnosis codes from electronic health records for identifying leukemia in children and adolescents has high PPV and sensitivity if more than one code is required.
PEDIATRIC BLOOD & CANCER
(2022)
Article
Computer Science, Information Systems
A. Ram, Clair A. Kronk, Jacob R. Eleazer, Joseph L. Goulet, Cynthia A. Brandt, Karen H. Wang
Summary: Transgender individuals often face harassment and harm in healthcare settings, with gender-related terminology in electronic health records potentially exacerbating harm and failing to accommodate nonbinary patients.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2021)
Article
Biochemical Research Methods
Michael J. Kane, Casey King, Denise Esserman, Nancy K. Latham, Erich J. Greene, David A. Ganz
Summary: This paper presents a novel dataset of numerical representations for ICD-10-CM codes generated using a language model and autoencoder. These datasets can enable more advanced analyses in the biomedical domain and have the potential to significantly improve the utility of ICD-10-CM codes.
BMC BIOINFORMATICS
(2023)
Article
Gastroenterology & Hepatology
Calvin X. Geng, Anuragh R. Gudur, Daniel R. Patterson, Matthew J. Stotts
Summary: The diagnostic accuracy of ICD codes for alcoholic hepatitis (AH) is limited. Studies using the ICD codes should be interpreted cautiously.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Computer Science, Information Systems
Kin Wah Fung, Julia Xu, Shannon McConnell-Lamptey, Donna Pickett, Olivier Bodenreider
Summary: The study found that the ICD-11 can fully represent approximately 23.5% of the most frequently used ICD-10-CM codes without postcoordination, and with postcoordination support, it can fully represent about 35.2% of the codes. Most conflicts resulted from differences in granularity and default coding assumptions between the ICD-11 and ICD-10-CM.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2021)
Article
Rheumatology
Anthony Dolomisiewicz, Hanifah Ali, Punyasha Roul, Yangyuna Yang, Grant W. Cannon, Brian Sauer, Joshua F. Baker, Ted R. Mikuls, Kaleb Michaud, Bryant R. England
Summary: The study aims to update and validate the Rheumatic Disease Comorbidity Index (RDCI) using International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) codes. The study demonstrates that the proposed ICD-10-CM codes can generate comparable RDCI scores to those derived from ICD-9-CM codes, and are highly predictive of functional status and death.
ARTHRITIS CARE & RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Anna Schuh-Renner, Matthew C. Inscore, Veronique D. Hauschild, Bruce H. Jones, Michelle Canham-Chervak
Summary: The transition from ICD-9-CM to ICD-10-CM affected U.S. military injury surveillance, resulting in increased injury rates among soldiers, especially in cumulative microtraumatic injuries.
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Stephanie A. A. Leonard, Danielle M. M. Panelli, Jeffrey B. B. Gould, Alison Gemmill, Elliott K. K. Main
Summary: This study assessed the validity of diagnosis codes for week of gestation in the International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) among live births. The results showed high concordance and accuracy of these codes when compared with the best obstetric estimate on the birth certificate.
Article
Public, Environmental & Occupational Health
Li-Ying Wu, Shih-Chieh Shao, Shu-Chen Liao
Summary: This study aimed to determine the coding accuracy of myocarditis in Taiwan using ICD-10-CM codes. The overall positive predictive value (PPV) of the myocarditis codes was 73.5%, but some other inflammation diseases and pre-existing heart diseases may be falsely coded as myocarditis.
CLINICAL EPIDEMIOLOGY
(2023)
Article
Medicine, Research & Experimental
Muzammil H. Syed, Mohammed Al-Omran, Jean Jacob-Brassard, Joel G. Ray, Mohamad A. Hussain, Muhammad Mamdani, Charles de Mestral
Summary: The study estimated the positive predictive value (PPV) of Canadian ICD-10 diagnostic coding for identifying hospitalization related to a diabetic foot ulcer (DFU). The results showed that the DSFUG group had the highest PPV, indicating it as an effective identification method.
CLINICAL AND INVESTIGATIVE MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Meng-Chen Hsu, Chi-Chuan Wang, Ling-Ya Huang, Chih-Ying Lin, Fang-Ju Lin, Sengwee Toh
Summary: The study evaluated the effect of diagnostic coding system transition on the identification of common conditions recorded in Taiwan's national claims database. Results showed that less than half of the 32 conditions studied had a smooth transition between the ICD-9-CM and ICD-10-CM coding systems, researchers should be aware of inconsistencies in coding definitions.
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
(2021)
Article
Endocrinology & Metabolism
Ajay Bhasin, Hannah Nam, Chen Yeh, Jungwha Lee, David Liebovitz, Chad Achenbach
Article
Biochemical Research Methods
Samir Rachid Zaim, Colleen Kenost, Joanne Berghout, Wesley Chiu, Liam Wilson, Hao Helen Zhang, Yves A. Lussier
BMC BIOINFORMATICS
(2020)
Article
Medicine, General & Internal
Ramon Lorenzo-Redondo, Hannah H. Nam, Scott C. Roberts, Lacy M. Simons, Lawrence J. Jennings, Chao Qi, Chad J. Achenbach, Alan R. Hauser, Michael G. Ison, Judd F. Hultquist, Egon A. Ozer
Review
Dermatology
Jeffrey D. Jenks, Hannah H. Nam, Martin Hoenigl
Summary: This review focuses on the epidemiology, definitions, diagnostic tests, clinical presentation, and imaging findings of invasive aspergillosis (IA) in critically ill patients in the intensive care unit, providing direction for further research.
Editorial Material
Ethics
Carol G. Gu, Elizabeth Lerner Papautsky, Andrew D. Boyd, John Zulueta
AMERICAN JOURNAL OF BIOETHICS
(2021)
Article
Biochemical Research Methods
Dillon Aberasturi, Nima Pouladi, Samir Rachid Zaim, Colleen Kenost, Joanne Berghout, Walter W. Piegorsch, Yves A. Lussier
Summary: The study proposes a new method, Inter-N-of-1, to identify meaningful differences between very small cohorts by using the effect size of 'single-subject-study'-derived responsive biological mechanisms. In both simulations and a clinical proof-of-concept dataset, Inter-N-of-1 showed high precision and recall in cohorts of 3 versus 3 distinct subjects, outperforming conventional methods at smaller sample sizes but being outperformed at larger sample sizes.
Article
Health Care Sciences & Services
Tre Tomaszewski, Alex Morales, Ismini Lourentzou, Rachel Caskey, Bing Liu, Alan Schwartz, Jessie Chin
Summary: The study found that false HPV vaccine information on social media mostly contained loss-framed messages focusing on the potential risk of vaccines using more diverse vocabulary, while true information was more diverse in topics. The convolutional neural network model outperformed other models in identifying false information.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Engineering, Biomedical
Scott C. Roberts, Hannah H. Nam, Rebecca N. Kumar, Tingqing Wu, Rebecca S. Harap, Duc Thinh Pham, Jonathan D. Rich, Valentina Stosor
Summary: This study aimed to evaluate the colonization of multidrug-resistant organisms (MDRO) in patients with ventricular assist devices (VAD) and its impact on patient outcomes. The results showed that MDRO colonization was common in VAD patients and was associated with an increased risk of future VAD infections.
Review
Critical Care Medicine
Hannah H. Nam, Michael G. Ison
Summary: RSV is a negative sense single-stranded RNA virus that can result in seasonal respiratory infections in humans. It can have severe clinical impact on hospitalized adults, leading to a wide range of symptoms and exacerbations of underlying diseases. While supportive care is the mainstay of therapy, there are multiple therapeutic and preventative options under development for RSV.
SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE
(2021)
Article
Biotechnology & Applied Microbiology
Ayokunle Olagoke, Rachel Caskey, Brenikki Floyd, Jennifer Hebert-Beirne, Andrew Boyd, Yamile Molina
Summary: Psychosocial factors such as perceived self-efficacy and perceived response efficacy are positively associated with HPV vaccination intention. Attitudes toward HPV vaccination mediate the relationship between self-efficacy/response efficacy and vaccination intention, suggesting that attitude-focused interventions may help overcome religious barriers to vaccination.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2021)
Article
Medicine, Research & Experimental
Ardith Z. Doorenbos, Judith M. Schlaeger, Victoria A. deMartelly, Larisa A. Burke, Andrew D. Boyd, Mitchell R. Knisely, Jonathan W. Leigh, Hongjin Li, Molly W. Mandernach, Robert E. Molokie, Crystal L. Patil, Alana D. Steffen, Nirmish Shah, Miriam O. Ezenwa
Summary: The GRACE study aims to evaluate the effectiveness of guided relaxation and acupuncture therapy in alleviating pain associated with sickle cell disease, as well as the implementation processes within healthcare systems. A total of 366 participants will be recruited and randomized into different groups, and assessments will be conducted at 6 weeks, 12 weeks, and 24 weeks. The results of this study will be critical in improving pain management for patients with sickle cell disease.
CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS
(2023)
Article
Health Care Sciences & Services
Heather Coats, Nadia Shive, Bonnie Adrian, Andrew Boyd, Ardith Z. Doorenbos, Sarah J. Schmiege
Summary: This study aims to evaluate the feasibility, usability, and effects of delivering a person-centered narrative intervention (PCNI) via electronic means in an outpatient setting. The study used a mixed method design and lasted for approximately 3 to 4 weeks. The results showed that a total of 20 patient participants and 7 clinician participants were enrolled. The findings from this study have the potential to influence clinical practices and policies and provide innovative avenues for more person-centered care.
JMIR RESEARCH PROTOCOLS
(2023)
Article
Computer Science, Information Systems
Andrew D. Boyd, Rosa Gonzalez-Guarda, Katharine Lawrence, Crystal L. Patil, Miriam O. Ezenwa, Emily C. O'Brien, Hyung Paek, Jordan M. Braciszewski, Oluwaseun Adeyemi, Allison M. Cuthel, Juanita E. Darby, Christina K. Zigler, P. Michael Ho, Keturah R. Faurot, Karen L. Staman, Jonathan W. Leigh, Dana L. Dailey, Andrea Cheville, Guilherme Del Fiol, Mitchell R. Knisely, Corita R. Grudzen, Keith Marsolo, Rachel L. Richesson, Judith M. Schlaeger
Summary: Embedded pragmatic clinical trials (ePCTs) play a vital role in addressing population health problems by utilizing electronic health record (EHR) systems to increase the speed and volume of relevant research. However, the growing number of ePCTs using EHR-derived data increases the risk of biases due to differences in data capture and access to care, perpetuating health inequalities. This article identifies 3 challenges - incomplete data on social determinants of health, lack of representation of vulnerable populations, and data loss due to variable technology use - that exacerbate bias when working with EHR data and provides recommendations and examples to actively mitigate bias.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2023)
Article
Computer Science, Information Systems
Vera C. Kaelin, Andrew D. Boyd, Martha M. Werler, Natalie Parde, Mary A. Khetani
Summary: This research aimed to develop and identify a predictive model for classifying caregiver strategies into participation-related constructs, using natural language processing. The best performing model was found to be a support vector machine (SVM) using term frequency-inverse document frequency (TF-IDF).
JOURNAL OF HEALTHCARE INFORMATICS RESEARCH
(2023)
Article
Health Care Sciences & Services
Haiquan Li, Edwin Baldwin, Xiang Zhang, Colleen Kenost, Wenting Luo, Elizabeth A. Calhoun, Lingling An, Charles L. Bennett, Yves A. Lussier
Summary: This study analyzed the risk of fatality for cancer patients with COVID-19, controlling for covariates such as age, sex, metastasis status, and cancer type. Results showed an overall HR of fatality of 7.76, with varying levels of risk among different cancer types. The study emphasizes the importance of prompt vaccination for uninfected cancer patients, especially for those most affected by COVID-19.
BMJ HEALTH & CARE INFORMATICS
(2021)