Article
Pediatrics
Xiaobo Ma, Ying Li, Mengshuang Lv, Jie Li, Shouqin Zhao
Summary: This study analyzed the results of two commonly selected tube insert positions for children with Otitis media with effusion (OME) and found that insertion in the posteroinferior quadrant (PQ) provided better outcomes. Compared to insertion in the anteroinferior quadrant (AQ), PQ insertion was more stable, improved hearing more effectively, and was more convenient for surgeons.
TRANSLATIONAL PEDIATRICS
(2022)
Article
Otorhinolaryngology
Yui Ogawa, Masaru Kunimoto, Sachio Takeno, Toru Sonoyama, Takashi Ishino, Takao Hamamoto, Tsutomu Ueda
Summary: The study found that the introduction of PCV7 and PCV13 reduced the incidence of MTTI in children around 1 year old, with more significant effects during the early periods. The results support the etiological evidence that pneumococcal infection may play a role in the pathogenesis of ComOM requiring MTTI in children aged 1 year and younger.
LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY
(2022)
Review
Otorhinolaryngology
Richard M. Rosenfeld, David E. Tunkel, Seth R. Schwartz
Summary: Objective insertion of tubes in an office setting and automated tube insertion devices were identified as quality improvement opportunities, but limited research evidence prevented making recommendations. The existing literature lacks sufficient studies on procedure setting, optimal technique, and long-term outcomes. The role of automated devices remains uncertain and further research is needed.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2022)
Article
Medicine, General & Internal
Jungho Ha, Ga Young Gu, Se Hyun Yeou, Hantai Kim, Oak-Sung Choo, Jeong Hun Jang, Hun Yi Park, Yun-Hoon Choung
Summary: This study examined the effects of different types of tympanostomy tubes in pediatric patients undergoing cleft palate surgery. The results showed that the Paparella type 1 tube was more effective in palatoplasty surgeries with lower recurrence rates, while the Paparella type 2 tube was associated with a higher risk of persistent eardrum perforation. For other surgeries, a larger size type 2 tube may be considered to reduce the frequency of recurrence and tube reinsertion.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Pediatrics
Mohammad Ali Hoghoughi, Tayebeh Kazemi, Ali Khojasteh, Raha Habibagahi, Zahra Kalkate, Zeynab Zarei, Hamidreza Hosseinpour, Maryam Salimi
Summary: This study evaluated the impact of intravelar veloplasty under magnification (Sommerlad's technique) on middle ear effusion in cleft palate patients without the need for tympanostomy tube insertion. The results showed a significant improvement in middle ear effusion after surgery, without the necessity for tympanostomy tube insertion.
Article
Otorhinolaryngology
Myung Hoon Yoo, Yang-Sun Cho, June Choi, Yun Hoon Choung, Jae-Ho Chung, Jong Woo Chung, Gyu Cheol Han, Beom Cho Jun, Dong-Kee Kim, Kyu Sung Kim, Jun Ho Lee, Kyu-Yup Lee, Seung Hwan Lee, In Seok Moon, Hong Ju Park, Shi Nae Park, Jihye Rhee, Jae Hyun Seo, Seung Geun Yeo
Summary: The type of ventilation tube, patient age, and effusion composition can affect the extrusion rate and recurrence rate of the tube.
CLINICAL AND EXPERIMENTAL OTORHINOLARYNGOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Su Young Jung, Dokyoung Kim, Dong Choon Park, Eun Hye Lee, Yong-Sung Choi, Jeewon Ryu, Sang Hoon Kim, Seung Geun Yeo
Summary: Otitis media is caused by various factors including infections, anatomo-physiological abnormalities, allergies, and environmental influences. This study highlights the immune responses in otitis media patients, focusing on antibodies and transcription factors produced by B cells, as well as the important functions of B cells in immune defense.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Correction
Medicine, General & Internal
Alexander E. Perl, Giovanni Martinelli, Jorge E. Cortes, Andreas Neubauer, Ellin Berman, Stefania Paolini, Pau Montesinos, Maria R. Baer, Richard A. Larson, Celalettin Ustun, Francesco Fabbiano, Harry P. Erba, Antonio Di Stasi, Robert Stuart, Rebecca Olin, Margaret Kasner, Fabio Ciceri, Wen-Chien Chou, Nikolai Podoltsev, Christian Recher, Hisayuki Yokoyama, Naoko Hosono, Sung-Soo Yoon, Je-Hwan Lee, Timothy Pardee, Amir T. Fathi, Chaofeng Liu, Nahla Hasabou, Xuan Liu, Erkut Bahceci, Mark J. Levis
Summary: The article contains errors in the numbers of patients receiving previous FLT3 inhibitor therapy and requires correction.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Medicine, General & Internal
Maria Dietrich, Heike Schade, Jennifer Nadal, Sabine Keiner, Goetz Schade
Summary: The study aimed to evaluate the presence of temporary threshold shifts (TTS) in children who have undergone intraoperative auditory brainstem response (ioABR) testing and to use prolonged latencies of wave I as an indicator of persisting air-bone gap. A total of 83 children who underwent ioABR at University Hospital Bonn, Germany, were included in the study. The results showed a higher risk of prolonged latency of wave I at 80-dB SPL in children with mucoid fluid compared to those without mucoid fluid. Therefore, caution should be exercised when interpreting ioABR results, taking into account sex differences, and verifying the findings. Preoperative discussion involving parents should consider postponing ioABR testing if mucoid fluid is present.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Otorhinolaryngology
Theodore O. Truitt, James R. Kosko, Grace L. Nimmons, Jay Raisen, Sandra M. Skovlund, Frank Rimell, Shelagh A. Cofer
Summary: In this study, in-office tympanostomy tube (TT) placement in awake children using a novel device was safe, successful, and well tolerated. The procedure was found to be acceptable by all children according to independent assessment by clinicians.
LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY
(2021)
Article
Otorhinolaryngology
Eoin F. Cleere, Thomas J. Crotty, John Lang, Orla Young, Ivan J. Keogh
Summary: This study aimed to improve local management of paediatric otitis media by using the 2022 AAO-HNS Clinical Practice Guideline for Tympanostomy Tubes in Children. Through educational intervention, adherence to the guidelines in local practice significantly increased.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2023)
Article
Medicine, Research & Experimental
Flora Yan, Arnav Shah, Glenn Isaacson
Summary: This study investigated the rate of tympanostomy tube (TT) placement in children with autism spectrum disorder (ASD) in the United States and explored potential factors associated with this rate. The results showed that children with ASD had a higher rate of TT placement compared to children without ASD. Possible reasons for this increased rate include higher infection rates in ASD, over-diagnosis of ear infection or hearing disability in a difficult-to-examine population, and a preference for aggressive treatment in this at-risk group.
Review
Biochemistry & Molecular Biology
Su Young Jung, Dokyoung Kim, Dong Choon Park, Sung Soo Kim, Tong In Oh, Dae Woong Kang, Sang Hoon Kim, Seung Geun Yeo
Summary: Otitis media is mainly caused by upper respiratory tract infection and eustachian tube dysfunction. The expression of Toll-like receptors (TLRs) is closely related to the occurrence, recurrence, chronicization, and complications of otitis media, playing an important role in the early response to external antigens.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Pediatrics
Chan Il Song, Byung Chul Kang, Chol Ho Shin, Yun Suk An, Tae Su Kim, Hyun Woo Lim, Hyun Joon Shim, Myung Hoon Yoo, Joong Ho Ahn
Summary: This study visualized and classified the clinical manifestations of OME using a new grading system, and found a significant correlation between the grading system and age at VTI, nature of middle ear effusion, recurrence rate of OME, and rate of revision VTI. The grade of the ear affected the duration of ventilation tube retention after VTI.
Article
Medicine, General & Internal
Susanna Esposito, Sonia Bianchini, Alberto Argentiero, Riccardo Gobbi, Claudio Vicini, Nicola Principi
Summary: Studies have shown a decline in incidence of acute otitis media (AOM) worldwide, but related medical, social, and economic problems still exist. Better knowledge of risk factors and accurate diagnosis are essential to further reduce disease incidence. New approaches and technologies are being proposed to improve AOM detection and diagnosis, including video-otoscopy and use of artificial intelligence.