Article
Surgery
Alexis L. Johns, Daniela V. Luquetti, Carrie L. Heike, Amelia F. Drake, Milagros M. Duenas Roque, Paula Hurtado-Villa, Harry Pachajoa, Gloria Liliana Porras-Hurtado, Ignacio Zarante, Leanne Magee
Summary: Children with craniofacial microsomia (CFM) are at risk for educational and social issues. This study investigated intervention services and teasing frequency in a multinational population of children with CFM, showing that access to intervention services was higher in the US compared to South America. Children were aware of their diagnosis around age 4 and experienced teasing starting around age 6, with most teasing occurring at school.
JOURNAL OF CRANIOFACIAL SURGERY
(2021)
Review
Surgery
Ruben W. Renkema, Cornelia J. J. M. Caron, Carrie L. Heike, Maarten J. Koudstaal
Summary: This article reviews a decade of clinical research studies on craniofacial microsomia (CFM), focusing on clinical features, medical interventions, and surgical interventions. The review highlights the increasing understanding of CFM diagnosis and management through the publication of numerous new studies in recent years. The clinical difficulties faced by CFM patients, including craniofacial and extracraniofacial characteristics, as well as the impact on breathing, feeding, speech, and hearing, are discussed. The importance of individualized treatment tailored to the diverse phenotypes of CFM patients is emphasized. Collaboration between craniofacial centers and the use of standardized registration and outcome measurement tools are suggested to enhance research and future care for CFM patients.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2022)
Article
Surgery
Ruben W. W. Renkema, Thymen Houwen, Christianne A. A. van Nieuwenhoven, Bonnie L. L. Padwa, Christopher R. R. Forrest, David J. J. Dunaway, Maarten J. J. Koudstaal, Cornelia J. J. M. Caron
Summary: This study analyzed the occurrence of upper and lower limb anomalies in CFM patients and examined the association between limb anomalies and the OMENS+ classification. The results showed that more than one in six CFM patients have limb anomalies. Therefore, clinical awareness and assessment of limb abnormalities in CFM patients are important.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Article
Surgery
Candace H. Chan, Allison C. Hu, Nirbhay S. Jain, Brian N. Dang, Mengyuan T. Liu, Anthony A. Bertrand, Libby F. Wilson, Justine C. Lee
Summary: This study aimed to analyze the prevalence, diagnosis, and management of velopharyngeal insufficiency (VPI) in patients with craniofacial microsomia (CFM). The results showed that VPI was present in 27.9% of all CFM patients, with differences in diagnosis and treatment between isolated CFM patients and those with cleft lip and/or palate.
JOURNAL OF CRANIOFACIAL SURGERY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Ruben W. Renkema, Irene van Beelen, Maarten J. Koudstaal, Cornelia J. J. M. Caron
Summary: This study aimed to investigate the potential progressiveness of mandibular asymmetry and factors influencing chin point deviation in patients with unilateral craniofacial microsomia. The findings suggest that craniofacial microsomia may be a non-progressive disorder, as chin point deviation did not change over time.
JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
(2022)
Article
Surgery
Karam A. Allam
Summary: This study reviewed the demographic characteristics and clinical findings of a group of Egyptian patients with HFM, demonstrating the phenotypic variability and suggesting a degree of relationship among the components of HFM. Some epidemiological aspects and clinical findings in this study did not always parallel those reported in western literatures. Further studies with larger sample sizes, possibly multi-center, are recommended.
JOURNAL OF CRANIOFACIAL SURGERY
(2021)
Article
Surgery
Ruben W. Renkema, Olivia K. C. Spivack
Summary: This article introduces the European guideline on craniofacial microsomia, which provides an overview of optimal care provisions and recommendations for improvement for patients.
JOURNAL OF CRANIOFACIAL SURGERY
(2022)
Article
Otorhinolaryngology
Tiffany T. Pham, Shanlee M. Davis, Suhong Tong, Khaled A. Campa, Norman R. Friedman, Sarah A. Gitomer
Summary: A retrospective cross-sectional study found a high prevalence of obstructive sleep-disordered breathing (oSDB) in young patients with Turner syndrome (TS), with a four-fold increased risk compared to the general pediatric population. Risk factors for oSDB in TS included adenoid, tonsillar, and inferior turbinate hypertrophy, birthweight, failure to thrive, and older age at the last clinic visit. Screening for oSDB and performing polysomnography in TS patients with associated risk factors and symptoms is crucial due to the potential exacerbation of behavioral problems, neurocognitive deficits, and growth impairment associated with oSDB.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Surgery
Ruben W. Renkema, V. de Vreugt, Carrie L. Heike, Bonnie L. Padwa, Christopher R. Forrest, David J. Dunaway, E. B. Wolvius, Cornelia J. J. M. Caron, Maarten J. Koudstaal
Summary: Characteristics of patients with craniofacial microsomia (CFM) vary in type and severity. The use of diagnostic criteria could improve research and communication among patients and healthcare professionals. FACIAL and ICHOM criteria accurately describe CFM patients.
JOURNAL OF CRANIOFACIAL SURGERY
(2023)
Article
Surgery
Beatriz Goncalves Ferraz, Siulan Vendramini-Pittoli, Luiz Paulo Gomes, Michele Madeira Brandao, Nivaldo Alonso, Cristiano Tonello
Summary: This study aimed to identify the frequency and morphology of spinal anomalies in individuals with clinical diagnoses of CFM and to correlate spinal anomalies with craniofacial involvement. The results showed that spinal anomalies are more common than usually reported in individuals with CFM and are significantly correlated with facial features, particularly the OMENS score.
JOURNAL OF CRANIOFACIAL SURGERY
(2023)
Article
Pediatrics
Eduardo Machado Rossi-Monteiro, Laura Rodrigues Sefair, Marcos Correia Lima, Maria Fernanda Lima Nascimento, Daniel Mendes-Pinto, Lukas Anschuetz, Maria Gloria Rodrigues-Machado
Summary: This study aimed to compare cardiovascular parameters between healthy children and those with obstructive sleep-disordered breathing (oSDB), as well as identify predictors of arterial stiffness indices in children with oSDB. Children with oSDB showed higher reflection coefficient and augmentation index compared to controls, indicating increased arterial stiffness. Multiple regression analysis revealed age, female sex, reflection coefficient, and systolic volume as independent predictors of augmentation index, while higher pulse wave velocity was associated with poorer quality of life.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Review
Critical Care Medicine
Salam Zeineddine, James A. Rowley, Susmita Chowdhuri
Summary: Sleep-disordered breathing (SDB) has significant cardiovascular and neurological effects, with supplemental oxygen therapy showing mixed results in improving oxygen saturation and apnea severity compared to positive airway pressure therapy. Further research is needed to clarify the optimal dose and duration of nocturnal supplemental oxygen (NSO) and its combination with PAP in improving cardiovascular, sleep, and cognitive outcomes in SDB patients.
Review
Clinical Neurology
Bethanie Menzies, Arthur Teng, Mary Burns, Suncica Lah
Summary: This systematic review with meta-analysis found that children with sleep disordered breathing (SDB) have significant impairments in multiple neurocognitive domains, with intelligence being the most affected. The severity of SDB, body mass index, age at testing, measurement method, and control group usage were identified as moderating factors. The study emphasizes the importance of further research and interventions for children with SDB.
SLEEP MEDICINE REVIEWS
(2022)
Article
Pediatrics
Neepa Gurbani, Christine L. Schuler, Daniel Ignatiuk, Jennifer Albrecht, Yuping Guo, Amanda Waits, Carolyn M. Kercsmar
Summary: A screening process for sleep disordered breathing (SDB) was successfully implemented using quality improvement methods in patients hospitalized for asthma exacerbation. The screening rate significantly increased, highlighting the importance of evaluating SDB in high-risk children.
PEDIATRIC PULMONOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
W. Rooijers, R. W. Renkema, S. E. Loudon, T. Khoshnaw, B. L. Padwa, D. J. Dunaway, M. J. Koudstaal, C. R. Forrest, C. J. J. M. Caron
Summary: This multicentre retrospective cohort study aimed to describe and categorize ocular and adnexal anomalies in patients with CFM, finding that 33.9% of patients had ocular anomalies. Results showed a correlation between higher OMENS-Plus and Pruzansky-Kaban scores and an increased risk of ocular anomalies. Targeted ophthalmological screening and increased awareness of the possibility of ocular anomalies in CFM patients are important for clinical practice.
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
(2021)
Article
Public, Environmental & Occupational Health
Corey M. Benedum, Mahsa M. Yazdy, Samantha E. Parker, Allen A. Mitchell, Martha M. Werler
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2016)
Meeting Abstract
Gastroenterology & Hepatology
Douglas Mogul, Simon Ling, Yona K. Cloonan, Karen F. Murray, Philip Rosenthal, Norberto Rodriguez-Baez, Sarah Jane Schwarzenberg, Jeffrey Teckman, Qian Zhao, Lilia Ganova-Raeva, Lili Punkova, Kathleen B. Schwarz
Article
Peripheral Vascular Disease
Sarah C. Fisher, Alissa R. Van Zutphen, Martha M. Werler, Angela E. Lin, Paul A. Romitti, Charlotte M. Druschel, Marilyn L. Browne
Article
Gastroenterology & Hepatology
Sarah Jane Schwarzenberg, Simon C. Ling, Yona Keich Cloonan, Hsing-Hua S. Lin, Donna M. Evon, Karen F. Murray, Norberto Rodriguez-Baez, Philip Rosenthal, Jeffrey Teckman, Kathleen B. Schwarz
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
(2017)
Editorial Material
Public, Environmental & Occupational Health
Martha M. Werler, Samantha E. Parker
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
(2017)
Article
Surgery
Matthew L. Speltz, Erin R. Wallace, Brent R. Collett, Carrie L. Heike, Daniela V. Luquetti, Martha M. Werler
PLASTIC AND RECONSTRUCTIVE SURGERY
(2017)
Article
Dentistry, Oral Surgery & Medicine
Baiyang Sun, Yona K. Cloonan, Brent R. Collett, Matthew L. Speltz
CLEFT PALATE-CRANIOFACIAL JOURNAL
(2017)
Article
Developmental Biology
Samantha E. Parker, Martha M. Werler, Mika Gissler, Helja-Marja Surcel
BIRTH DEFECTS RESEARCH
(2017)
Article
Dentistry, Oral Surgery & Medicine
Erin R. Wallace, Brent R. Collett, Carrie L. Heike, Martha M. Werler, Matthew L. Speltz
CLEFT PALATE CRANIOFACIAL JOURNAL
(2018)
Article
Environmental Sciences
Marco Vinceti, Carlotta Malagoli, Martha M. Werler, Tommaso Filippini, Gianfranco De Girolamo, Grazia Ghermandi, Sara Fabbi, Gianni Astolfi, Sergio Teggi
ENVIRONMENTAL RESEARCH
(2018)
Article
Dentistry, Oral Surgery & Medicine
Erin R. Wallace, Brent R. Collett, Carrie L. Heike, Martha M. Werler, Matthew L. Speltz
CLEFT PALATE CRANIOFACIAL JOURNAL
(2018)
Article
Developmental Biology
Stephanie Dukhovny, Carla M. Van Bennekom, David R. Gagnon, Sonia Hernandez Diaz, Samantha E. Parker, Marlene Anderka, Martha M. Werler, Allen A. Mitchell
BIRTH DEFECTS RESEARCH
(2018)
Article
Public, Environmental & Occupational Health
Susan B. Brogly, Sonia Hernandez-Diaz, Emily Regan, Ela Fadli, Kristen A. Hahn, Andmartha M. Werler
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2018)
Article
Public, Environmental & Occupational Health
Julia D. Interrante, Elizabeth C. Ailes, Jennifer N. Lind, Marlene Anderka, Marcia L. Feldkamp, Martha M. Werler, Lockwood G. Taylor, James Trinidad, Suzanne M. Gilboa, Cheryl S. Broussard
ANNALS OF EPIDEMIOLOGY
(2017)
Article
Public, Environmental & Occupational Health
Stephen M. Kerr, Samantha E. Parker, Allen A. Mitchell, Sarah C. Tinker, Martha M. Werler
ANNALS OF EPIDEMIOLOGY
(2017)