期刊
TRENDS IN FOOD SCIENCE & TECHNOLOGY
卷 42, 期 2, 页码 97-115出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tifs.2014.12.007
关键词
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资金
- Salvador de Madariaga mobility program from the Ministerio de Educacion (Government of Spain)
- CIBERobn from the Instituto de Salud Carlos III (Madrid, Spain)
- MINECO (Government of Spain) [AGL2013-45554-R]
- Linea Especial Nutricien, Obesidad y Salud from the University of Navarra [LE197]
A personalized nutritional approach, based not only on phenotypic traits but also on genetic make-up, may help to control body weight and obesity. Recent advances in nutrigenetics, bioinformatics and genome-wide association/metabolomic/metagenomic studies are set to unleash a revolution in personalized nutrition. This article performs a systematic review of nutrigenetic data concerning single nucleotide polymorphisms (SNPs) involved in weight loss that are considered polygenic. SNPs located in or near FTO, MC4R, MC3R, POMC, LEP, LEPR, PLIN1, AP0A5, LIPC, FABP2, IN5IG2, IRS 1, GIPR, ADBR2, ADRB3, UCP1, RETN, ADIPOQ, IL6, PPARG, TCF7L2, and CLOCK, among others, are comprehensively reviewed.
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