Fetal metabolic programming and epigenetic modifications: a systems biology approach

Early maternal undernutrition programs increased feed intake, altered glucose metabolism and insulin secretion, and liver function in aged female offspring

(2012) Lindsey A. George et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Programming of adipose tissue miR-483-3p and GDF-3 expression by maternal diet in type 2 diabetes

(2012) D Ferland-McCollough et al.   CELL DEATH AND DIFFERENTIATION

Cardiovascular disease is associated with high-fat-diet-induced liver damage and up-regulation of the hepatic expression of hypoxia-inducible factor 1α in a rat model

(2012) Adriana L. Burgueño et al.   CLINICAL SCIENCE

Gestational weight gain

(2012) Lucilla Poston   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Epigenetic changes in fetal hypothalamic energy regulating pathways are associated with maternal undernutrition and twinning

(2012) Ghazala Begum et al.   FASEB JOURNAL

Maternal high-fat intake during pregnancy programs metabolic-syndrome-related phenotypes through liver mitochondrial DNA copy number and transcriptional activity of liver PPARGC1A

(2012) Adriana Laura Burgueño et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Insulin-Like Growth Factor 2/H19 Methylation at Birth and Risk of Overweight and Obesity in Children

(2012) Ellen Perkins et al.   JOURNAL OF PEDIATRICS

Text-mining solutions for biomedical research: enabling integrative biology

(2012) Dietrich Rebholz-Schuhmann et al.   NATURE REVIEWS GENETICS

microRNA Regulatory Network Inference Identifies miR-34a as a Novel Regulator of TGF-β Signaling in Glioblastoma

(2012) Giannicola Genovese et al.   Cancer Discovery

MicroRNA Regulation of SIRT1

(2012) Munekazu Yamakuchi   Frontiers in Physiology

PESCADOR, a web-based tool to assist text-mining of biointeractions extracted from PubMed queries

(2011) Adriano Barbosa-Silva et al.   BMC BIOINFORMATICS

Epigenetic Gene Promoter Methylation at Birth Is Associated With Child's Later Adiposity

(2011) K. M. Godfrey et al.   DIABETES

miR-16 and miR-21 Expression in the Placenta Is Associated with Fetal Growth

(2011) Matthew A. Maccani et al.   PLoS One

OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes

(2011) J. S. You et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ALTERED BODY MASS REGULATION IN MALEmPeriodMUTANT MICE ON HIGH-FAT DIET

(2010) Robert Dallmann et al.   CHRONOBIOLOGY INTERNATIONAL

Prenatal hypoxia independent of undernutrition promotes molecular markers of insulin resistance in adult offspring

(2010) E. J. Camm et al.   FASEB JOURNAL

Epigenetic regulation of insulin resistance in nonalcoholic fatty liver disease: Impact of liver methylation of the peroxisome proliferator-activated receptor γ coactivator 1α promoter

(2010) Silvia Sookoian et al.   HEPATOLOGY

High fat diet-induced liver steatosis promotes an increase in liver mitochondrial biogenesis in response to hypoxia

(2010) Julieta Carabelli et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Methylation of TFAM gene promoter in peripheral white blood cells is associated with insulin resistance in adolescents

(2010) Carolina Gemma et al.   MOLECULAR GENETICS AND METABOLISM

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function

(2010) David Warde-Farley et al.   NUCLEIC ACIDS RESEARCH

Losartan reduces liver expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced rat nonalcoholic fatty liver disease model

(2009) Maria Soledad Rosselli et al.   ATHEROSCLEROSIS

The impact of maternal high-fat feeding on liver and abdominal fat accumulation in adult offspring under a long-term high-fat diet

(2009) Adriana L. Burgueño et al.   HEPATOLOGY

Influence of hepatocyte nuclear factor 4α (HNF4α) gene variants on the risk of type 2 diabetes: A meta-analysis in 49,577 individuals

(2009) Silvia Sookoian et al.   MOLECULAR GENETICS AND METABOLISM

Maternal Pregestational BMI Is Associated With Methylation of thePPARGC1APromoter in Newborns

(2009) Carolina Gemma et al.   Obesity

The nuclear receptor PXR gene variants are associated with liver injury in nonalcoholic fatty liver disease

(2009) Silvia Sookoian et al.   Pharmacogenetics and Genomics

Genetic variants in STAT3 are associated with nonalcoholic fatty liver disease

(2008) Silvia Sookoian et al.   CYTOKINE

Maternal and Postnatal Overnutrition Differentially Impact Appetite Regulators and Fuel Metabolism

(2008) Hui Chen et al.   ENDOCRINOLOGY

A putative physiological role of hypothalamic CNTF in the control of energy homeostasis

(2008) C.-M. Vacher et al.   FEBS LETTERS

Non-alcoholic fatty liver disease is strongly associated with carotid atherosclerosis: A systematic review

(2008) Silvia Sookoian et al.   JOURNAL OF HEPATOLOGY

A Decreased Mitochondrial DNA Content Is Related to Insulin Resistance in Adolescents

(2008) Tomas F. Gianotti et al.   Obesity