4.6 Review

Pathological Calcification and Replicating Calcifying-Nanoparticles: General Approach and Correlation

期刊

PEDIATRIC RESEARCH
卷 67, 期 5, 页码 490-499

出版社

NATURE PUBLISHING GROUP
DOI: 10.1203/PDR.0b013e3181d476ce

关键词

-

资金

  1. National Aeronautics and Space Administration

向作者/读者索取更多资源

Calcification, a phenomenon often regarded by pathologists little more than evidence of cell death, is becoming recognized to be important in the dynamics of a variety of diseases from which millions of beings suffer in all ages. In calcification, all that is needed for crystal formation to start is nidi (nuclei) and an environment of available dissolved components at or near saturation concentrations, along with the absence of inhibitors for crystal formation. Calcifying nanoparticles (CNP) are the first calcium phosphate mineral containing particles isolated from human blood and were detected in numerous pathologic calcification related diseases. Controversy and critical role of CNP as nidi and triggering factor in human pathologic calcification are discussed. (Pediatr Res 67: 490-499, 2010)

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据