期刊
TRENDS IN BIOCHEMICAL SCIENCES
卷 40, 期 1, 页码 1-3出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibs.2014.10.010
关键词
bioinformatics; systems biology; proteomics; transcriptomics
资金
- NATIONAL CANCER INSTITUTE [U24CA160019] Funding Source: NIH RePORTER
- NCI NIH HHS [U24-CA-160019, U24 CA160019] Funding Source: Medline
Transcriptomic, proteomic, and metabolomic measurements are revolutionizing the way we model and predict cellular behavior, and multi-omic comparisons are being published with increased regularity. Some have expected a trivial and predictable correlation between mRNA and protein; however, the manifest complexity of biological regulation suggests a more nuanced relationship. Indeed, observing this lack of strict correlation provides clues for new research topics, and has the potential for transformative biological insight.
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