Gordon Syndrome: a continuing story

Phosphorylation Decreases Ubiquitylation of the Thiazide-sensitive Cotransporter NCC and Subsequent Clathrin-mediated Endocytosis

(2014) Lena L. Rosenbaek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The WNK-SPAK/OSR1 pathway: Master regulator of cation-chloride cotransporters

(2014) D. R. Alessi et al.   Science Signaling

Chemical library screening for WNK signalling inhibitors using fluorescence correlation spectroscopy

(2013) Takayasu Mori et al.   BIOCHEMICAL JOURNAL

The CUL3–KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction

(2013) Akihito Ohta et al.   BIOCHEMICAL JOURNAL

Regulation of with-no-lysine kinase signaling by Kelch-like proteins

(2013) Shinichi Uchida et al.   BIOLOGY OF THE CELL

Extrarenal roles of the with-no-lysine[K] kinases (WNKs)

(2013) Keith Siew et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Detection of mutations inKLHL3andCUL3in families with FHHt (familial hyperkalaemic hypertension or Gordon's syndrome)

(2013) Mark Glover et al.   CLINICAL SCIENCE

Phosphorylation Regulates NCC Stability and Transporter Activity In Vivo

(2013) S.-S. Yang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

WNK1-related Familial Hyperkalemic Hypertension results from an increased expression of L-WNK1 specifically in the distal nephron

(2013) E. Vidal-Petiot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cullin-3 Regulates Vascular Smooth Muscle Function and Arterial Blood Pressure via PPARγ and RhoA/Rho-Kinase

(2012) Christopher J. Pelham et al.   Cell Metabolism

Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities

(2012) Lynn M. Boyden et al.   NATURE

KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron

(2012) Hélène Louis-Dit-Picard et al.   NATURE GENETICS

The molecular basis of blood pressure variation

(2012) Hakan R. Toka et al.   PEDIATRIC NEPHROLOGY

The activity of the thiazide-sensitive Na+–Cl– cotransporter is regulated by protein phosphatase PP4

(2010) Mark Glover et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

WNK4 Enhances the Degradation of NCC through a Sortilin-Mediated Lysosomal Pathway

(2009) B. Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Whole-genome association study identifies STK39 as a hypertension susceptibility gene

(2008) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA