Article
Chemistry, Physical
Tae Gwang Yun, Jaehyeong Bae, Hyeon Gyun Nam, Dongyeon Kim, Ki Ro Yoon, Seung Min Han, Il-Doo Kim
Summary: The PEDOT:PSS-based transpiration-driven electrokinetic power generator (p-TEPG) demonstrates higher energy density and enhanced volumetric and areal energy/power densities compared to carbon-based TEPG. The p-TEPG utilizes cations to establish additional potential difference in the polymer matrix, maximizing energy generation efficiencies. Seawater produced on a single p-TEPG device is sufficient to charge electrical energy storage systems and operate low-powered electronic devices.
Article
Engineering, Chemical
Masashi Iwata, Kazuya Shimoizu, Haruna Sadai, Tomohiro Iwasaki, Kazuho Nakamura, Mohammed Saedi Jami
Summary: This study focused on the electrokinetic phenomena during expression operation of zinc oxide slurry, and found that the absolute value of EPD began to decline at the end of the filtration period and reached a plateau at the end of consolidation. By extending the theoretical equation of streaming potential to a tortuous flow path, the time course of EPD can be qualitatively explained considering medium resistance based on conventional filtration and consolidation theories.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Engineering, Environmental
Minsoo Lee, Woonjae Choi, Geunbae Lim
Summary: This study proposes an electrokinetic-assisted filtration method to address the issues of membrane filtration, and demonstrates outstanding filtration performance in removing microplastics.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Medicine, General & Internal
Barbara J. Ballermann, Jenny Nystrom, Borje Haraldsson
Summary: Inflammatory activation and dysfunction of the glomerular endothelium can lead to proteinuria in various vascular disorders. The barrier function of the glomerular endothelium is mainly attributed to the endothelial glycocalyx/endothelial surface layer.
FRONTIERS IN MEDICINE
(2021)
Article
Biophysics
Urban Ajdnik, Thomas Luxbacher, Lidija Fras Zemljic
Summary: Controlling protein adsorption on biomaterial surfaces is crucial for successful biointegration. In this study, a combination of electrokinetic measurements and quartz crystal microbalance was used to understand the adsorption phenomena of blood proteins on polysaccharide-based biointerfaces. The results show that the functionalized surfaces have suppressed protein affinity compared to hydrophobic surfaces.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Hematology
Numpong Punyaratabandhu, Panadda Dechadilok, Wannapong Triampo, Pisut Katavetin
Summary: This study examines the effects of physiological and hemodynamic factor alterations associated with diabetic nephropathy (DN) on glomerular permselectivity using a mathematical model. The results indicate that glomerular hypertension and the reduction in oncotic pressure decrease glomerular macromolecule filtration, while reduction of renal plasma flow rate (RPF) and changes in the glomerular barrier structure associated with DN increase solute sieving. Damage to glycosaminoglycans (GAGs) caused by hyperglycemia is likely to be the most prominent factor affecting glomerular size-selectivity.
Article
Mechanics
Bibaswan Dey, G. P. Raja Sekhar
Summary: This study aims to investigate the role of endothelial-cell glycocalyx layer in the transport of blood-borne solutes and the effects of interface potential and charge density on plasma flow rate and solute transport. Various experimental observations suggest that EGL holds negative charges and interacts with blood plasma. The study utilizes biphasic mixture theory and analytical methods to analyze the interactions between plasma and EGL.
Article
Immunology
Qing Ye, Dongjie Wang, Chao Zhou, Hanyan Meng, Huihui Liu, Jianhua Mao
Summary: Idiopathic nephrotic syndrome (INS) is a common renal disease characterized by disruption of the glomerular filtration barrier. In a previous study, podocyte autoantibodies were identified in INS patients, leading to the concept of autoimmune podocytopathy. This study aims to investigate the presence of autoantibodies against vascular endothelial cells in INS patients and assess their clinical significance and pathogenicity. Screening of INS patient sera revealed nine types of autoantibodies against vascular endothelial cells, potentially causing endothelial cell damage. Additionally, 89% of the patients tested positive for at least one autoantibody.
CLINICAL IMMUNOLOGY
(2023)
Article
Chemistry, Analytical
Alaleh Vaghef-Koodehi, Olivia D. Ernst, Blanca H. Lapizco-Encinas
Summary: This paper presents the first continuous separation of microparticles and cells with similar characteristics using linear and nonlinear electrokinetic phenomena in an insulator-based electrokinetic (iEK) system. By combining mathematical modeling and experimentation, four distinct binary mixtures of particles and cells were successfully separated. The results demonstrate good reproducibility and illustrate the potential of the iEK system for efficient separation.
ANALYTICAL CHEMISTRY
(2023)
Article
Cell Biology
Andreas Pannek, Janine Becker-Gotot, Steven K. Dower, Anne M. Verhagen, Paul A. Gleeson
Summary: This study investigates the endocytic trafficking pathway of FcRn-albumin in primary vascular endothelial cells, and finds that it is mainly internalized through fluid-phase macropinocytosis and co-localizes with FcRn in acidic endosomal structures, before being transported to the plasma membrane through FcRn-positive tubules.
JOURNAL OF CELL SCIENCE
(2023)
Review
Physiology
Natalie C. Finch, Chris R. Neal, Gavin I. Welsh, Rebecca R. Foster, Simon C. Satchell
Summary: The fenestrations of glomerular endothelial cells (GEnCs) are crucial for the function of the glomerular filtration barrier. This review provides an update on the current understanding of the regulation and biogenesis of fenestrations and discusses the diseases in which loss of GEnC fenestrations may contribute to loss of glomerular filtration function. The literature reviewed includes studies on GEnCs as well as other cell types with similar fenestration structures, such as liver sinusoidal endothelial cells.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
(2023)
Review
Neurosciences
Ora A. Weisz
Summary: The article describes the mechanism of protein recycling in the renal tubules and its behavior in different states, proposing an integrated new working model that explains the role of fluid phase uptake in recovering high concentrations of protein in conditions of impaired filtration barrier. This model considers the independent pathways of fluid phase and receptor-mediated uptake, as well as the impact of protein load on physiological and pathological states.
JOURNAL OF PHYSIOLOGY-LONDON
(2021)
Article
Chemistry, Multidisciplinary
Yanhong Pan, Bing Lu, Ying Peng, Minghui Wang, Ying Deng, Yongmei Yin, Jie Yang, Genxi Li
Summary: A simple electrochemical method has been proposed in this study for the assay of tumor cells based on their steric hindrance effect. Cancer cells can be quantitatively analyzed without complicated design or operation, with a detection limit of about 53 cells per mL. The method also shows satisfactory performance in complex environments, indicating its potential for clinical application.
CHEMICAL COMMUNICATIONS
(2021)
Article
Physics, Applied
Qin Zeng, Dequan Xu, Wenbo Wu, Yaoming Wang, Qinlong Ren
Summary: In this research, a multi-physical theoretical model was constructed to study the electrokinetic purification of oil-in-water emulsions with modulation of temperature and pH. The results showed that the purification effectiveness of oil-in-water emulsions can be improved by lowering the temperature, increasing the ion concentration, and neutralizing the pH. This study provides a theoretical understanding of the electrokinetic purification of oil-in-water emulsions and contributes to its development for industrial applications.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2023)
Article
Chemistry, Analytical
Xinbang Jiang, Boya Ma, Momo Sun, Chen Guo, Zhuang Liu, Yunzheng Du, Biao Wang, Nan Li, Mengya Chen, Yanjia Zhang, Jie Shen, Lailiang Ou
Summary: In this study, a novel IMNs platform was developed by biomimetic protein corona precoating and polyethylene glycol (PEG) spacer, forming PEG and corona-coated IMNs (IP-CMNs). The IP-CMNs demonstrated a dual stealth effect, reducing nonspecific protein adsorption and cell binding, and enhancing capture performance towards tumor cells.
ANALYTICAL CHEMISTRY
(2023)