Article
Public, Environmental & Occupational Health
Shazia Moosa, Ammar Ali Muhammad, Sohail Dogar, Sundus Iftikhar, Walter Johnson, Asad Latif, Lubna Samad
Summary: The study showed that with standardized training protocols and close monitoring, nonphysician health providers were able to safely perform circumcisions on infants aged three months or younger. Older infants were more likely to experience adverse events, with minor events including bell failure to shed and minimal bleeding.
BULLETIN OF THE WORLD HEALTH ORGANIZATION
(2021)
Article
Medicine, General & Internal
M. Jose Carrera, Pedro Moliner, Gemma Llaurado, Cristina Enjuanes, Laura Conangla, Juan-Jose Chillaron, Silvia Ballesta, Elisenda Climent, Josep Comin-Colet, Juana-Antonia Flores-Le Roux
Summary: Acute hyperglycemia is associated with worse prognosis in patients hospitalized for heart failure. The acute-to-chronic glycemic ratio is significantly associated with mortality in subjects hospitalized for acute HF, with improved predictive ability compared to glucose levels at admission or average chronic glucose concentrations, especially in subjects with diabetes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Noriaki Moriyama, Teemu Laakso, Peter Raivio, Sebastian Dahlbacka, Eeva-Maija Kinnunen, Tatu Juvonen, Antti Valtola, Annastiina Husso, Maina P. Jalava, Tuomas Ahvenvaara, Tuomas Tauriainen, Jarkko Piuhola, Asta Lahtinen, Matti Niemela, Timo Makikallio, Marko Virtanen, Pasi Maaranen, Markku Eskola, Mikko Savontaus, Juhani Airaksinen, Fausto Biancari, Mika Laine
Summary: The study found that in patients without chronic kidney disease, those who underwent transcatheter aortic valve replacement (TAVR) had a significantly lower incidence of acute kidney injury (AKI) compared to surgical aortic valve replacement (SAVR) patients. AKI significantly increased the risk of 5-year mortality after either TAVR or SAVR, and the severity of AKI was associated with a higher 5-year mortality rate.
CANADIAN JOURNAL OF CARDIOLOGY
(2021)
Article
Mathematics
Bence Czako, Daniel Andras Drexler, Levente Kovacs
Summary: Type 1 Diabetes Mellitus (T1DM) is a disease that requires exogenous insulin administration due to obstructed insulin production in the pancreas. A control strategy based on RFPT and SMD was designed to automate the insulin delivery process. The algorithm showed promising results in regulating blood glucose levels, but further modifications and validation are needed for practical use.
Article
Medicine, General & Internal
Josefa Alarcon, Jacob Guzman, Telma S. Masuko, Pablo Navarro Caceres, Ramon Fuentes
Summary: Mesiodens are the most common supernumerary teeth, often detected incidentally. The etiology is unclear, but genetic factors may play a role. Timely diagnosis is crucial to avoid clinical complications.
Article
Cardiac & Cardiovascular Systems
Gabriele Crimi, Vincenzo De Marzo, Federico De Marco, Federico Conrotto, Jacopo Oreglia, Fabrizio D'Ascenzo, Luca Testa, Riccardo Gorla, Giuseppe Esposito, Sabato Sorrentino, Carmen Spaccarotella, Francesco Soriano, Francesco Bruno, Matteo Vercellino, Manrico Balbi, Nuccia Morici, Ciro Indolfi, Gaetano Maria De Ferrari, Francesco Bedogni, Italo Porto
Summary: After transcatheter aortic valve replacement (TAVR), acute kidney injury (AKI) is associated with increased mortality, independently affecting the primary outcome along with chronic kidney disease (CKD).
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Endocrinology & Metabolism
Borko Stojanovic, Marta Bizic, Marko Bencic, Miroslav L. Djordjevic
Summary: This study aimed to evaluate the surgical treatment and outcomes of adult patients with non-urethral complications after hypospadias repair in childhood. A total of 97 patients were analyzed, with a mean age of 22.5 years. The study found that non-urethral complications can occur many years after the initial surgery and have a significant impact on quality of life. Treatment usually involves a radical surgical approach to correct all associated deformities and achieve successful cosmetic and psychosexual outcomes. Erectile dysfunction was reported in 24% of the patients.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Medicine, General & Internal
Shanshan Sun, Wenyi Ye, Ruihong Zhao, Jianhua Hu, Xuan Zhang, Meifang Yang, Hong Zhao, Jifang Sheng
Summary: This study found that the use of PPI in hospitalized cirrhosis patients does not appear to increase mortality or the risk of hepatic encephalopathy and spontaneous bacterial peritonitis.
FRONTIERS IN MEDICINE
(2021)
Article
Endocrinology & Metabolism
Kobi Gorin, Avivit Cahn, Michal Leibovitch, Shachar Peled, Ofer Perzon, Keren Tzukert, Amir Haze, Ofer Elishoov, Karen Olshtain-Pops, Yechiel Nisan Gelman
Summary: Limited data is available on diabetic foot ulcers in patients after solid organ transplantation, especially kidney transplantation. This study compared the clinical presentation and outcomes of kidney transplant patients to non-kidney transplant patients in a diabetic foot unit. The results showed that post-transplant patients did not have worse outcomes despite immunosuppressive therapy.
DIABETES-METABOLISM RESEARCH AND REVIEWS
(2022)
Article
Biochemistry & Molecular Biology
Marek Saracyn, Adam Daniel Durma, Barbara Bober, Arkadiusz Lubas, Maciej Kolodziej, Waldemar Kapusta, Beata Dmochowska, Grzegorz Kaminski
Summary: Neuroendocrine tumors (NEN) are a group of neoplasms that arise from hormonal and neural cells. Despite a common origin, their clinical symptoms and outcomes are varied. Targeted radioligand therapy (RLT) is a treatment option which has proven to be successful in recent studies. However, the possible outcomes and true safety profile of the treatment need to be fully determined, especially by new, more sensitive methods.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Endocrinology & Metabolism
Sigridur Bjornsdottir, Steven Ing, Deborah M. Mitchell, Tanja Sikjaer, Line Underbjerg, Zaki J. Hassan-Smith, Jad Sfeir, Neil J. Gittoes, Bart L. L. Clarke
Summary: Chronic hypoparathyroidism is a rare disorder characterized by low serum calcium, increased serum phosphorus, and decreased parathyroid hormone. The epidemiology and complications of this disorder are not well understood, but it is associated with significant morbidity and a substantial financial burden.
JOURNAL OF BONE AND MINERAL RESEARCH
(2022)
Review
Biochemistry & Molecular Biology
Bilal Bashir, Jan H. Ho, Paul Downie, Paul Hamilton, Gordon Ferns, Dev Datta, Jaimini Cegla, Anthony S. Wierzbicki, Charlotte Dawson, Fiona Jenkinson, Hannah Delaney, Michael Mansfield, Yee Teoh, Zosia Miedzybrodzka, Haya Haso, Paul N. Durrington, Handrean Soran
Summary: This article reviews the genetic basis of chylomicronaemia, the difference between monogenic and polygenic hypertriglyceridaemia, its effects on pancreatic, cardiovascular, and microvascular complications, and current and potential future pharmacotherapies.
Review
Medicine, General & Internal
Murad Kheetan, Iheanyichukwu Ogu, Joseph Shapiro, Zeid J. Khitan
Summary: Hyponatremia is a common electrolyte disorder in clinical practice, and proper treatment requires understanding of the patient's hypotonic state and cerebral defense mechanisms, differentiation and management based on urine analysis, electrolytes, and volume status.
FRONTIERS IN MEDICINE
(2021)
Review
Biochemistry & Molecular Biology
Kamila Raziyeva, Yevgeniy Kim, Zharylkasyn Zharkinbekov, Kuat Kassymbek, Shiro Jimi, Arman Saparov
Summary: Skin wounds significantly impact the global healthcare system, with acute and chronic wounds being the two main types. The immune response is crucial for acute wound healing, but dysregulation can lead to chronic wounds characterized by persistent inflammation and delayed healing. Current research focuses on immunomodulatory therapeutic strategies to improve wound healing, targeting factors such as macrophage phenotype and inflammatory mediators.
Article
Pediatrics
Zainab Bashir, Isabel M. Butt, Murali K. Vemuri, Tarekegn Geberhiwot
Summary: This report highlights a case of acute psychosis in a 16-year-old boy with mild SARS-CoV-2 infection, emphasizing the need for vigilance in pediatric patients. While neuropsychiatric manifestations have been well documented in adults with SARS-CoV-2 infections, there are few reports in the pediatric population.