Article
Biology
Ruey-Chih Su, Jyh-Gang Leu, Yuan-Hsin Chen, Chao-Yi Chen, Yi-Feng Yang, Chih-Cheng Yen, Shiu-Huey Chou, Yao-Jen Liang
Summary: This study investigated the effect of Antrodia cinnamomea ointment on diabetic wound healing using animal models and found that topical application of the ointment can significantly promote wound healing. The study also explored the mechanism by analyzing protein expressions related to angiogenesis.
Article
Pediatrics
Guanglun Zhou, Jianchun Yin, Junjie Sun, Wenbin Zhu, Shiyang Jin, Shou-lin Li
Summary: This study compared the efficacy of once-daily and twice-daily application of 0.1% mometasone furoate in children with symptomatic severe phimosis. The results showed that the twice-daily regimen had a higher success rate in the early stage of treatment, but there was no difference between the two groups at 4 weeks and 3 months. In addition, topical steroid therapy was more effective in children with lower-grade phimosis.
FRONTIERS IN PEDIATRICS
(2022)
Article
Pharmacology & Pharmacy
Saeed Ali Alsareii, Nasser A. N. Alzerwi, Mansour Yousef Alasmari, Abdulrahman Manaa Alamri, Mater H. Mahnashi, Ibrahim Ahmed Shaikh, Chetan Savant, Preeti V. Kulkarni, Arun K. Shettar, Joy H. Hoskeri, Vijay Kumbar
Summary: M. zapota extract exhibits antibacterial and antioxidant properties that enhance wound healing. In vitro and in vivo experiments demonstrated that M. zapota extract accelerates wound contraction, epithelization, collagen proliferation, and cell migration. These findings highlight the significant wound-healing potential of M. zapota extract.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Microbiology
Raeesa Faisthalab, Suganthi Suppiah, Morna Dorsey, Kathleen E. Sullivan, Joseph Icenogle, Ludmila Perelygina
Summary: A strong association between rubella virus and chronic granulomas in individuals with inborn errors of immunity has been confirmed. The antiviral drug nitazoxanide (NTZ) was highly effective against both the RA27/3 vaccine and wild-type RuV strains in vitro. However, NTZ treatment as a salvage therapy did not improve cutaneous granulomas associated with RuV in patients. Investigation of treatment failures in two ataxia-telangiectasia patients revealed that live immunodeficiency-related vaccine-derived rubella viruses (iVDRVs) were still present in granulomas before and after treatment, despite a reduction in RuV RNA. The low sensitivities of iVDRVs to NTZ were likely the cause of treatment failures, rather than the emergence of resistance.
Article
Dermatology
Carolina Alexander-Savino, Catherine G. Chung, Elaine S. Gilmore, Sean M. Carroll, Brian Poligone
Summary: This study aimed to evaluate the effectiveness of 0.1% triamcinolone ointment in reducing contact dermatitis associated with the use of mechlorethamine/chlormethine gel for the treatment of MF. The results showed that triamcinolone ointment increased the tolerability of mechlorethamine/chlormethine gel without affecting its efficacy.
DERMATOLOGY AND THERAPY
(2022)
Article
Cell Biology
Fan Yang, Xuenan Liu, Donghao Wei, Yuan Zhu, Feilong Wang, Xuejiao Liu, Fanyu Yan, Xiao Zhang, Yunsong Liu
Summary: Bone defects and fractures heal slowly, causing a burden on patients, families, and society. The external application of butyl flufenamate ointment can accelerate the healing of cranial defects in mice by promoting BMP2 secretion.
Article
Dermatology
Diala M. Alshiyab, Firas A. Al-qarqaz, Jihan M. Muhaidat, Yousef S. Alkhader, Ruba F. Al-sheyab, Sala I. Jafaar
Summary: This study aimed to assess the synergic effect of pseudocatalase/superoxide dismutase (PSD) gel when combined with Tacrolimus 0.1% ointment versus Tacrolimus 0.1% alone for the treatment of vitiligo. The results showed that adding PSD to Tacrolimus ointment did not provide any additional therapeutic benefit in children with limited vitiligo.
JOURNAL OF DERMATOLOGICAL TREATMENT
(2022)
Article
Medicine, General & Internal
Ayasha Iram, Raheel Tahir, Aliya Akhtar, Madiha Mariam, Zahra Zafar
Summary: This study compared the efficacy and safety of bimatoprost 0.03% with mometasone furoate 0.1% in the treatment of alopecia areata involving eyebrows, scalp, and beard. The results showed that patients treated with mometasone furoate had better hair regrowth within 3 months of treatment and were free from any documented side effects.
ANNALS OF KING EDWARD MEDICAL UNIVERSITY LAHORE PAKISTAN
(2023)
Article
Chemistry, Applied
Hamdoon A. Mohammed, Salman A. A. Mohammed, Omar Khan, Hussein M. Ali
Summary: This study evaluated the wound healing activity of eucalyptol in a rat's third-degree skin-burn model. The results showed that after 1 and 2 weeks of eucalyptol treatment, there was accelerated wound healing, reduced edema, and antioxidant and anti-inflammatory effects.
JOURNAL OF OLEO SCIENCE
(2022)
Article
Medicine, General & Internal
Ayasha Iram, Raheel Tahir, Aliya Akhtar, Madiha Mariam, Zahra Zafar
Summary: This study aimed to compare the efficacy and safety of 0.03% bimatoprost with 0.1% mometasone furoate in the treatment of alopecia areata involving eyebrows, scalp and beard. The results showed that the mometasone furoate group had a better treatment response, with a higher percentage of hair regrowth and faster recovery, while the bimatoprost group is devoid of any documented side effects.
ANNALS OF KING EDWARD MEDICAL UNIVERSITY LAHORE PAKISTAN
(2023)
Article
Orthopedics
Sonmez Saglam, Zafer Orhan, Mehmet Arican, Yalcin Turhan, Zekeriya Okan Karaduman, Yildiray Tekce, Muecahid Osman Yucel
Summary: This study aimed to investigate the effects of tranexamic acid (TA) on wound healing in a rat model. The results showed that local or intravenous application of TA may have positive effects on fibroblast count and wound contraction.
JOINT DISEASES AND RELATED SURGERY
(2023)
Article
Dermatology
Daniel T. Yoksa, Yusuf Abba, Bala U. Shamaki, Ngamarju A. Satumari
Summary: This study evaluated the effects of resveratrol topical ointment on wound healing in full-thickness burn wounds. The results showed that resveratrol ointment enhanced wound contraction and tissue repair, and ameliorated burn-induced liver and kidney injuries.
JOURNAL OF WOUND CARE
(2022)
Article
Dermatology
Sanjeev Handa, Ariganesh Chandrasegaran, Amrinder Jit Kanwar, Rahul Mahajan
Summary: The study suggests that fluticasone cream and tacrolimus ointment are similarly effective and safe for the treatment of pediatric atopic dermatitis (AD) and prevention of its relapse.
INDIAN JOURNAL OF PAEDIATRIC DERMATOLOGY
(2022)
Review
Medicine, General & Internal
Jian-Wen Xu, Hong Qiang, Ting-Li Li, Yi Wang, Xiao-Xiao Wei, Fei Li
Summary: In bone surgery, both topical and intravenous TXA are equally effective in reducing blood loss compared to placebo, and both TXA forms can significantly reduce the need for blood transfusion. There is no significant difference between topical and intravenous TXA in their efficacy in promoting wound healing after surgery.
WORLD JOURNAL OF CLINICAL CASES
(2021)
Article
Education, Scientific Disciplines
Tathagata Adhikary, Chowdhury Mobaswar Hossain, Sougata Mallick, Samrat Paul, Nisha Banerjee, Piyali Basak
Summary: The study aimed to extract bioactive components from turmeric rhizomes and evaluate its therapeutic potential. The results showed significant antioxidant activity and cytotoxicity against human breast cancer cells of the extract. Turmeric ointment demonstrated good wound healing ability in incision and excision models.
INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH
(2021)