Article
Psychology, Developmental
Kris Evers, Jarymke Maljaars, Sarah J. Carrington, Alice S. Carter, Francesca Happe, Jean Steyaert, Susan R. Leekam, Ilse Noens
Summary: The study identified significant variability in the number and nature of sub-criteria covered by the three diagnostic instruments adapted from DSM-5, along with differences in algorithm development, cut-off scores, and adherence to DSM-5 decision-making rules for diagnostic classification. The differences in interpreting DSM-5 criteria present a challenge for symptom operationalization, which can be effectively overcome through consensus, testing, and reformulation.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2021)
Article
Psychology, Developmental
Laura L. Corona, Liliana Wagner, Madison Hooper, Amy Weitlauf, Tori E. Foster, Jeffrey Hine, Alexandra Miceli, Amy Nicholson, Caitlin Stone, Alison Vehorn, Zachary Warren
Summary: This study investigates two approaches to tele-assessment for autism spectrum disorder (ASD) in toddlers and finds a diagnostic agreement of 92%. Children inaccurately identified as having ASD by tele-assessment were younger and had higher developmental and adaptive behavior scores than children accurately diagnosed with ASD. Both clinicians and families reported satisfaction with tele-assessment procedures.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Article
Behavioral Sciences
Duangkamol Tangviriyapaiboon, Samai Sirithongthaworn, Hataichanok Apikomonkon, Chidawan Suyakong, Pimwarat Srikummoon, Suttipong Kawilapat, Patrinee Traisathit
Summary: The Thai Diagnostic Autism Scale is a reliable tool for the early diagnosis of Autism Spectrum Disorder in Thai children, showing good content validity, diagnostic agreement, and inter-rater reliability. Further large-scale studies are needed to determine its efficacy and appropriate cut-off point.
Article
Multidisciplinary Sciences
Victor Ardulov, Victor R. Martinez, Krishna Somandepalli, Shuting Zheng, Emma Salzman, Catherine Lord, Somer Bishop, Shrikanth Narayanan
Summary: This research utilizes machine learning models and Q-learning algorithm to construct clinical tools with interpretability and robustness, aiding in complex clinical diagnoses. Through simulating the differentiation process of developmental disorders in children, it demonstrates how to train more robust classifiers by maximizing accuracy and minimizing information required.
SCIENTIFIC REPORTS
(2021)
Article
Health Care Sciences & Services
Duangkamol Tangviriyapaiboon, Suttipong Kawilapat, Samai Sirithongthaworn, Hataichanok Apikomonkon, Chidawan Suyakong, Pimwarat Srikummoon, Salinee Thumronglaohapun, Patrinee Traisathit
Summary: The study aimed to find the optimal cut-off point for the Thai Diagnostic Autism Scale (TDAS) in diagnosing autism spectrum disorder (ASD) and compare its agreement with the DSM-5 ASD criteria. The findings showed that TDAS had higher diagnostic accuracy than ADOS-2 and TDAS domain. Diagnosis using this cut-off point could be useful in practical assessments.
Article
Psychology, Developmental
Kristen T. MacKenzie, Carla A. Mazefsky, Shaun M. Eack
Summary: Obtaining a diagnosis of autism spectrum disorder (ASD) can be challenging for parents. This study aimed to understand the diagnostic process and its influence on parent satisfaction. Findings showed that parents had developmental concerns early on, but faced long wait times and multiple appointments. The study provides insight for improving the diagnostic process.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2022)
Review
Neurosciences
Maria J. Ayoub, Laura Keegan, Helen Tager-Flusberg, Simone V. Gill
Summary: Research suggests that neuroimaging can reliably identify structural and functional differences between autistic and non-autistic brains at an early stage. Neuroimaging methods can also be used to predict ASD diagnosis among high-risk infants and their developmental outcomes in later stages.
Article
Genetics & Heredity
Meredith Cola, Lisa D. Yankowitz, Kimberly Tena, Alison Russell, Leila Bateman, Azia Knox, Samantha Plate, Laura S. Cubit, Casey J. Zampella, Juhi Pandey, Robert T. Schultz, Julia Parish-Morris
Summary: Autistic girls use significantly more social words than boys during a diagnostic assessment, despite being matched on age, IQ, and autism symptom severity. Sex differences in linguistic markers of social phenotype in autism are important for understanding the unique presentation of autistic girls and the potential challenges in their diagnosis and referral.
Article
Neurosciences
Azadeh Kushki, Robyn E. Cardy, Sina Panahandeh, Mahan Malihi, Christopher Hammill, Jessica Brian, Alana Iaboni, Margot J. Taylor, Russell Schachar, Jennifer Crosbie, Paul Arnold, Elizabeth Kelley, Muhammad Ayub, Robert Nicolson, Stelios Georgiades, Jason P. Lerch, Evdokia Anagnostou
Summary: The study discovered associations between social communication abilities and distributed cortical and subcortical networks implicated in social behaviors, language, attention, memory, and executive functions, as well as three data-driven, diagnosis-agnostic subgroups based on the patterns of association in these networks.
Article
Genetics & Heredity
Rotem Tal-Ben Ishay, Apurba Shil, Shirley Solomon, Noa Sadigurschi, Hadeel Abu-Kaf, Gal Meiri, Hagit Flusser, Analya Michaelovski, Ilan Dinstein, Hava Golan, Nadav Davidovitch, Idan Menashe
Summary: WES is an effective approach to identify the susceptibility of genetic variants of autism spectrum disorder (ASD). This study applied WES to a population-based sample of Bedouin and Jewish children with ASD in southern Israel, and found a diagnostic yield of 15.4%. The most cost-effective genetic testing method was chromosomal microarray analysis (CMA).
Article
Psychology, Multidisciplinary
Kirsten Corden, Rebecca Brewer, Eilidh Cage
Summary: The study found that self-perception and personal identity of autistic adults change over time after receiving a diagnosis, with dissatisfaction with autism potentially leading to lower self-esteem, and pride in autism potentially leading to higher self-esteem. Content analysis also revealed an emotive post-diagnostic adjustment process.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Psychology, Developmental
Maria Luisa Scattoni, Martina Micai, Antonio Ciaramella, Tommaso Salvitti, Francesca Fulceri, Laura Maria Fatta, Luise Poustka, Robert Diehm, Georgi Iskrov, Rumen Stefanov, Quentin Guillon, Bernadette Roge, Anthony Staines, Mary Rose Sweeney, Andrew Martin Boilson, Thora Leosdottir, Evald Saemundsen, Irma Moilanen, Hanna Ebeling, Anneli Yliherva, Mika Gissler, Tarja Parviainen, Pekka Tani, Rafal Kawa, Astrid Vicente, Celia Rasga, Magdalena Budisteanu, Ian Dale, Carol Povey, Noelia Flores, Cristina Jenaro, Maria Luisa Monroy, Patricia Garcia Primo, Tony Charman, Susanne Cramer, Christine Kloster Warberg, Ricardo Canal-Bedia, Manuel Posada, Diana Schendel
Summary: Research on autistic adult services is limited, with a disparity between the recommended features for diagnostic evaluation and post-diagnostic support services. While more than half of respondents experienced most recommended features for diagnostic evaluation, less than 2% of adults or carers, and less than 21% of professionals experienced each recommended feature for post-diagnostic support. This highlights significant gaps between good practice guidelines and the reality of services experienced by autistic adults and professionals.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2021)
Article
Psychiatry
Anita Brito, Felipe Franco, Helena Brentani, Patricia Cristina Baleeiro Beltrao-Braga
Summary: This study collected data on family history and environmental factors from 2,141 individuals with Autism Spectrum Disorders (ASD) in Brazil. Multiple Correspondence Analysis and Cluster Analysis revealed the interplay between genetics and environment. The results showed that genetic background, social and psychological factors played significant roles in ASD, but it was not possible to isolate patients based on genetic vulnerability or environmental exposure. Instead, a continuum of different compositions of genetic and environmental interplay was observed.
Article
Neurosciences
Loredana Benedetto, Francesca Cucinotta, Roberta Maggio, Eva Germano, Roberta De Raco, Ausilia Alquino, Caterina Impallomeni, Rosamaria Siracusano, Luigi Vetri, Michele Roccella, Massimo Ingrassia, Antonella Gagliano
Summary: Some studies suggest that the diagnosis of Autism Spectrum Disorder is reliable and stable in children aged 18 to 24 months. However, the stability of early ASD diagnosis needs further confirmation. This observational study examines the one-year diagnostic stability of autism spectrum disorder diagnosis in a clinical sample of children diagnosed between 18 and 48 months of age.
Article
Psychology, Developmental
Richard Vuijk, Mathijs Deen, Arnoud Arntz, Hilde M. Geurts
Summary: This study conducted a psychometric evaluation of a new diagnostic instrument for ASD, NIDA, in adult males in the Netherlands, showing high interrater agreement, promising convergent validity, and adequate concurrent criterion-related validity. These findings can serve as a foundation for future psychometric studies of NIDA in a more diverse population.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2022)
Article
Pediatrics
Rebecca R. Seltzer, Simone Thompson
PEDIATRIC CLINICS OF NORTH AMERICA
(2024)
Article
Pediatrics
Kimberly E. Sawyer, Douglas J. Opel
PEDIATRIC CLINICS OF NORTH AMERICA
(2024)
Article
Pediatrics
Micah Hester, Skye A. Miner
Summary: The process of soliciting a minor's assent has moral importance, even if it is not always required by regulations. It allows the child's opinion to be heard and respects their development and involvement in research. The extent of the child's involvement depends on their age, experience, and maturity.
PEDIATRIC CLINICS OF NORTH AMERICA
(2024)
Article
Pediatrics
Nicholas A. Jabre, Margaret R. Moon
PEDIATRIC CLINICS OF NORTH AMERICA
(2024)
Article
Pediatrics
Carrie M. Henderson, Renee D. Boss
Summary: An increasing number of children with serious/complex illness are living with long-term prognostic uncertainty, intensive interactions with medical systems, functional limitations, and the use of chronic medical technologies that affect their quality of life. These families often face multiple medical decision points and rely on intentional and iterative discussions to guide their care goals.
PEDIATRIC CLINICS OF NORTH AMERICA
(2024)
Article
Pediatrics
Margaret R. Moon
PEDIATRIC CLINICS OF NORTH AMERICA
(2024)
Article
Pediatrics
Mark T. Hughes
PEDIATRIC CLINICS OF NORTH AMERICA
(2024)
