Article
Cardiac & Cardiovascular Systems
Sulayman el Mathari, Noor Boulidam, Frederiek de Heer, Laurent de Kerchove, Hans-Joachim Schaefers, Emmanuel Lansac, Jos W. R. Twisk, Jolanda Kluin
Summary: This study investigated the predictive value of aortic valve cusp retraction, calcification, and fenestration for the feasibility of aortic valvuloplasty. The results showed that all three factors were associated with an increased rate of switch to valve replacement, with calcification and retraction also being related to recurrence of severe aortic regurgitation.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Medicine, General & Internal
Shirit Kazum, Mordehay Vaturi, Idit Yedidya, Shmuel Schwartzenberg, Olga Morelli, Keren Skalsky, Hadas Ofek, Ram Sharony, Ran Kornowski, Yaron Shapira, Alon Shechter
Summary: Little is known about the natural history of non-significant mitral and tricuspid regurgitation (MR and TR) following surgical aortic valve replacement (SAVR) for aortic regurgitation (AR). This study retrospectively analyzed 184 patients who underwent SAVR for AR and found that about one fifth of patients developed significant MR/TR within six years, which correlated with worse cardiac condition and survival, and could be predicted by baseline clinical and echocardiographic variables.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Victor Quentin, Jules Mesnier, Clemence Delhomme, Neila Sayah, Paul Guedeney, Olivier Barthelemy, Gaspard Suc, Jean-Philippe Collet
Summary: Transcatheter mitral valve replacement (TMVR) is an emerging field dedicated to addressing the therapeutic challenges posed by patients at high surgical risk with mitral valve disease. TMVR can be categorized into TMVR with transcatheter aortic valves (TAV) and TMVR with dedicated devices. This field is gradually surmounting technical challenges and numerous devices are currently undergoing clinical trials.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Marianna Buonocore, Pieter De Meester, Marius Brusselmans, Tim Van Puyvelde, Anton Verrijcken, Filip Rega, Tom Verbelen
Summary: The study aimed to assess the evolution of secondary tricuspid regurgitation (TR) after isolated aortic valve replacement (AVR) and its impact on mortality, as well as to identify possible predictors of persistent TR and TR de novo. The results showed that patients with TR >= 2 had worse long-term survival after AVR, especially in older age groups. Age was also a predictor of persistent TR after AVR. Some patients developed TR de novo after isolated AVR, but this did not affect survival.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Jun Shi, Lai Wei, Yucheng Chen, Xu Wang, Jian Ye, Chaoyi Qin, Lulu Liu, Hong Qian, Chunsheng Wang, Yingqiang Guo
Summary: The study showed good midterm outcomes of transcatheter aortic valve implantation with the J-Valve system in treating patients with aortic stenosis or pure aortic insufficiency, suggesting it as a promising alternative therapy for high-risk patients.
ANNALS OF THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Enrico Poletti, Ole De Backer, Andrea Scotti, Giuliano Costa, Francesco Bruno, Claudia Fiorina, Nicola Buzzatti, Alessia Latini, Tanja K. Rudolph, Mark M. P. van den Dorpel, Christina Brinkmann, Kush P. Patel, Vasileios Panoulas, Joachim Schofer, Arturo Giordano, Marco Barbanti, Damiano Regazzoli, Maurizio Taramasso, Francesco Saia, Andreas Baumbach, Francesco Maisano, Nicolas M. Van Mieghem, Lars Sondergaard, Azeem Latib, Ignacio J. Amat Santos, Francesco Bedogni, Luca Testa
Summary: This study investigated the performance of new-generation transcatheter heart valves (THVs) in patients treated for pure severe native aortic valve regurgitation (NAVR). The results showed that TAVR for pure severe NAVR remains challenging with significant risk for complications.
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Cardiac & Cardiovascular Systems
Yang Liu, Mengen Zhai, Yu Mao, Chennian Xu, Yanyan Ma, Lanlan Li, Ping Jin, Jian Yang
Summary: This study examines the early experience with transcatheter aortic valve replacement (TAVR) in patients with quadricuspid aortic valve (QAV). The results demonstrate that TAVR is a feasible treatment option for QAV patients with acceptable early outcomes.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Taishi Okuno, Caglayan Demirel, Daijiro Tomii, Gabor Erdoes, Dik Heg, Jonas Lanz, Fabien Praz, Rainer Zbinden, David Reineke, Lorenz Raber, Stefan Stortecky, Stephan Windecker, Thomas Pilgrim
Summary: This study aimed to evaluate the risk of noncardiac surgery after TAVI. The results suggest that noncardiac surgery can be performed early after successful TAVI, and device performance may impact the risk of adverse outcomes after surgery.
Review
Cardiac & Cardiovascular Systems
Sahoor A. Khan, Suzanne J. Baron
Summary: Approximately 2% of people aged 70 to 83 in the United States suffer from moderate or severe aortic regurgitation, with up to 8% of eligible patients not receiving treatment. While transcatheter devices specifically for AR are still in development, off-label use of current TAVI devices has shown acceptable safety and efficacy for severe AR treatment in inoperable patients.
Review
Cardiac & Cardiovascular Systems
Waqas Ullah, Abdul-Rahman M. Suleiman, Heba Osman, Sairamya Bodempudi, Hamza Zahid Ullah Muhammadzai, Salman Zahid, Mohamed Zghouzi, Yasar Sattar, Salim S. Virani, David L. Fischman, M. Chadi Alraies
Summary: This study analyzed data from the Nationwide Readmissions Database and found that patients undergoing transcatheter aortic valve implantation (TAVI) for aortic insufficiency had higher rates of in-hospital clinical events, mortality, major bleeding, and valvular complications compared to those undergoing TAVI for aortic stenosis. However, there were no significant differences in these complications at 30-day and 180-day follow-up.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Hirokazu Onishi, Masaki Izumo, Toru Ouchi, Haruhito Yuki, Toru Naganuma, Tatsuya Nakao, Sunao Nakamura
Summary: This retrospective study examined the clinical effects of aortic valve replacement (AVR) in patients with moderate mixed aortic valve disease (MAVD). The study found that approximately half of the patients eventually required AVR and patients who underwent AVR had a significantly lower rate of the primary endpoint compared to those managed with medical treatment.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Medicine, General & Internal
Xavier Freixa, Rami Gabani, Pedro Cepas-Guillen, Eduardo Flores-Umanzor, Rodrigo Estevez-Loureiro, Eustaquio Maria Onorato
Summary: Catheter-based closure is an effective and less invasive option for high-risk patients with symptomatic PVL regurgitation.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Brunilda Alushi, Stephan Ensminger, Eva Herrmann, Uemniye Balaban, Timm Bauer, Andreas Beckmann, Sabine Bleiziffer, Helge Moellmann, Thomas Walther, Raffi Bekeredjian, Christian Hamm, Friedhelm Beyersdorf, Stephan Baldus, Andreas Boening, Volkmar Falk, Holger Thiele, Christian Frerker, Alexander Lauten
Summary: Patients with severe aortic stenosis often have mitral regurgitation, which interferes with the standard echocardiographic measurements of aortic stenosis. This study investigates the prevalence and severity of mitral regurgitation in patients with severe aortic stenosis and its impact on the accuracy of echocardiographic measurements.
CLINICAL RESEARCH IN CARDIOLOGY
(2022)
Article
Multidisciplinary Sciences
Chi Zhou, Zongyi Xia, Yanxu Song, Zhexun Lian
Summary: This study compared the outcomes of transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in patients with pure aortic regurgitation (AR). The results showed that TAVR had a lower risk of in-hospital mortality, but a higher risk of permanent pacemaker implantation compared to SAVR. TAVR was found to be a safe and feasible option for pure AR patients.
Editorial Material
Cardiac & Cardiovascular Systems
Piotr Nikodem Rudzinski, Markus Mach, Christoph Gross, Martin Andreas
Summary: A 70-year-old female underwent transcatheter aortic valve replacement and transcatheter mitral valve repair due to severe native aortic regurgitation and moderate-to-severe secondary mitral regurgitation, with successful outcomes and uneventful follow-up.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2021)