Prognostic implications of mutations inNOTCH1andFBXW7in childhood T-all treated according to the NOPHO ALL-1992 and ALL-2000 protocols

Prognostic Significance ofNOTCH1andFBXW7Mutations in Pediatric T-ALL

(2013) Yucel Erbilgin et al.   DISEASE MARKERS

Impact of complex NOTCH1 mutations on survival in paediatric T-cell leukaemia

(2012) Marcela Braga Mansur et al.   BMC CANCER

Clinical Impact ofNOTCH1and/orFBXW7Mutations,FLASHDeletion, andTCRStatus in Pediatric T-Cell Lymphoblastic Lymphoma

(2012) Celine Callens et al.   JOURNAL OF CLINICAL ONCOLOGY

Impact of NOTCH1/FBXW7 mutations on outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on the MRC UKALL 2003 trial

(2012) S Jenkinson et al.   LEUKEMIA

The indicative effect of Notch1 expression for the prognosis of T-cell acute lymphocytic leukemia: a systematic review

(2012) Jiexian Ma et al.   MOLECULAR BIOLOGY REPORTS

Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia

(2011) A. Staffas et al.   BLOOD

Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study

(2011) M. Schrappe et al.   BLOOD

Pediatric-inspired intensified therapy of adult T-ALL reveals the favorable outcome of NOTCH1/FBXW7 mutations, but not of low ERG/BAALC expression: a GRAALL study

(2011) R. Ben Abdelali et al.   BLOOD

Minimal residual disease assessment in childhood acute lymphoblastic leukaemia: a Swedish multi-centre study comparing real-time polymerase chain reaction and multicolour flow cytometry

(2011) Ingrid Thörn et al.   BRITISH JOURNAL OF HAEMATOLOGY

Transcriptional control of T-cell development

(2011) T. Naito et al.   INTERNATIONAL IMMUNOLOGY

Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed–Sternberg cells

(2011) R Schwarzer et al.   LEUKEMIA

NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols

(2010) L Zuurbier et al.   LEUKEMIA

NOTCH1 and FBXW7 mutations have a favorable impact on early response to treatment, but not on outcome, in children with T-cell acute lymphoblastic leukemia (T-ALL) treated on EORTC trials 58881 and 58951

(2010) E Clappier et al.   LEUKEMIA

The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL–BFM 2000 protocol can be separated from FBXW7 loss of function

(2010) C Kox et al.   LEUKEMIA

FBXW7andNOTCH1mutations in childhood T cell acute lymphoblastic leukaemia and T cell non-Hodgkin lymphoma

(2009) Myoung-Ja Park et al.   BRITISH JOURNAL OF HAEMATOLOGY

Clinical and cytogenetic features of a population-based consecutive series of 285 pediatric T-cell acute lymphoblastic leukemias: Rare T-cell receptor gene rearrangements are associated with poor outcome

(2009) Kristina Karrman et al.   GENES CHROMOSOMES & CANCER

Regulation of PTEN by CK2 and Notch1 in primary T-cell acute lymphoblastic leukemia: rationale for combined use of CK2- and  -secretase inhibitors

(2009) A. Silva et al.   HAEMATOLOGICA

The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group

(2009) A Larson Gedman et al.   LEUKEMIA

Long-term results of NOPHO ALL-92 and ALL-2000 studies of childhood acute lymphoblastic leukemia

(2009) K Schmiegelow et al.   LEUKEMIA

FBXW7 mutation in adult T-cell and B-cell acute lymphocytic leukemias

(2008) Jee Hoon Song et al.   LEUKEMIA RESEARCH