Article
Dermatology
Jan Kottner, Kathrin Hillmann, Alexandra Fastner, Romy Conzade, Stephanie Heidingsfelder, Konrad Neumann, Ulrike Blume-Peytavi
Summary: Regular emollient application during the first year of life does not prevent the development of atopic dermatitis. A standardized skin care regimen does not delay skin barrier development or cause side effects.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Article
Dermatology
Wanbo Yue, Daian Cheng, Zhe Sun, Yihang Shen, Shangshang Wang, Xiumei Liu, Xiaoping Pei, Sisi Deng, Hongju Pan, Zhigang Liao, Wei Li, Xu Yao, Yunsheng Liang, Zhiqiang Song, Zhirong Yao, Hui Zhang, Yifeng Guo
Summary: This study aimed to validate the diagnostic efficacy of three sets of AD criteria in adult and elderly Chinese populations in a hospital setting. The Chinese criteria of atopic dermatitis for children (CCAD) showed high sensitivity and favorable diagnostic efficacy, making it suitable for the diagnosis of atopic dermatitis in adult and elderly Chinese populations, particularly for mild and moderate cases of the condition.
BRITISH JOURNAL OF DERMATOLOGY
(2023)
Article
Dermatology
L. von Kobyletzki, N. Ballardini, D. Henrohn, M. P. Neary, G. Ortsater, K. Geale, A. Rieem Dun, I. Lindberg, A. De Geer, P. Neregard, A. Cha, J. C. Cappelleri, W. Romero, J. P. Thyssen
Summary: This study describes the longitudinal care pathways of patients with atopic dermatitis (AD), including healthcare management, treatment patterns, and disease progression. The results show that healthcare contacts and AD treatments are concentrated in the year when managed AD care is initiated and decrease significantly thereafter. This suggests that patients with AD may be undertreated and monitored infrequently.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2022)
Article
Medicine, General & Internal
Jia-huan He, Xin-guo Zhao, Feng Sun, Wen-qi Peng, Huan-yun Li, Hui Li
Summary: This study aimed to investigate the preventive effects of oral administration of probiotics on the incidence and severity of atopic dermatitis (AD) in infants. The results showed that adding probiotics could favor the establishment of intestinal microecological balance in the neonatal period, thereby reducing the incidence of AD, decreasing the levels of serum immune indexes, and alleviating the severity of the disease.
ARCHIVES OF MEDICAL SCIENCE
(2023)
Article
Dermatology
Jingru Tian, Dingyao Zhang, Yi Yang, Yaqing Huang, Lu Wang, Xu Yao, Qianjin Lu
Summary: Epidemiological data on atopic dermatitis (AD) are lacking in nearly half of the countries worldwide. The global prevalence of AD is estimated to be 2.6% with a total population of 204.05 million people. AD affects both adults and children, with prevalence rates of 2.0% and 4.0% respectively. Females have a higher prevalence of AD compared to males.
BRITISH JOURNAL OF DERMATOLOGY
(2023)
Article
Medicine, General & Internal
Sarah Preis, Lea Schmidt, Linda Tizek, Maximilian Schielein, Viktoria Lang, Rachela Bleuel, Anna Duswald, Sebastian Sitaru, Annette Blasini, Christine Gasteiger, Lennard Merdha, Zsuzsanna Kurgyis, Bettina Kuschel, Evelyn Hauenstein, Maximilian Sander, Sebastian Niedermeier, Desiree Argiriu, Sabrina Engel, Yuliya Skabytska, Rafaela L. Silva, Miriam Hils, Beatrix Evers, Susanne Kaesler, Hanna Hufnagel, Martin Koeberle, Yacine Amar, Alexander Zink, Tilo Biedermann
Summary: This study aims to comprehensively evaluate the relationship between environmental determinants and the risk of developing atopic dermatitis (AD) in the first four years of a child's life, including individual microbiome and immune responses. Through clinical research and biochemical analysis, the researchers hope to identify different risk factors for AD onset and exacerbation, as well as relevant biomarkers.
Article
Dermatology
K. M. A. Endre, L. Landro, M. LeBlanc, P. Gjersvik, K. C. Lodrup Carlsen, G. Haugen, G. Hedlin, C. M. Jonassen, B. Nordlund, K. Rudi, H. O. Skjerven, A. C. Staff, C. Soderhall, R. Vettukattil, E. M. Rehbinder
Summary: Diagnosing atopic dermatitis (AD) in infants is challenging, the study found that using the UK Working Party (UKWP) and Hanifin and Rajka (H&R) criteria can determine the incidence and persistence of eczema and AD. The odds of AD were lower when eczema first appeared at 6 or 12 months, and higher in infants with eczema at multiple visits.
BRITISH JOURNAL OF DERMATOLOGY
(2022)
Article
Pediatrics
Usha M. K. Sastry, M. Jayranganath, Raman Krishna Kumar, Santu Ghosh, A. P. Bharath, Anand Subramanian, Ameetkumar Managuli, Madhu Gangadhara, Cholenahally Nanjappa Manjunath
Summary: This study explores the clinical profile and management of thiamine-responsive acute pulmonary hypertension in infants. Among 250 infants with severe PH, 231 showed response to thiamine treatment, with significant improvement in symptoms and no recurrence of PH during 60 months follow-up.
ARCHIVES OF DISEASE IN CHILDHOOD
(2021)
Article
Nutrition & Dietetics
Philippa Davie, Debra Bick, Dharmintra Pasupathy, Sam Norton, Joseph Chilcot
Summary: The study found that mothers who give birth to macrosomic infants are more likely to exclusively breastfeed at birth and 2 weeks post-partum, but there were no significant associations between macrosomia and exclusive breastfeeding at 8 weeks or 4 months post-partum.
MATERNAL AND CHILD NUTRITION
(2021)
Article
Dermatology
Lina U. Ivert, Axel Svedbom, Maria Lundqvist, Carl-Fredrik Wahlgren, Maria Bradley, Emma K. Johansson
Summary: This study analyzed depressive symptoms among patients with atopic dermatitis undergoing systemic treatment and found that more than half of the patients had depressive symptoms. However, systemic treatment significantly reduced depressive symptoms and the positive effect lasted for 12 months.
ACTA DERMATO-VENEREOLOGICA
(2022)
Review
Allergy
Martin Steinhoff, Fareed Ahmad, Atul Pandey, Angeliki Datsi, Ayda AlHammadi, Sara Al-Khawaga, Aysha Al-Malki, Jianghui Meng, Majid Alam, Joerg Buddenkotte
Summary: Atopic dermatitis is a common chronic inflammatory skin disease, and its pathogenesis involves the dysregulation of neuroimmune circuits. Abnormal neuroimmune circuits can lead to inflammation, pruritus, pain, and skin barrier dysfunction. Understanding neuroimmune circuits and neuronal signaling is crucial for controlling the pathological mechanisms of atopic dermatitis.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2022)
Article
Nutrition & Dietetics
Ziming Yang, Yingfang Ding, Shuyao Song, Yaoyun Zhang, Aolin Li, Mintao Su, Yajun Xu
Summary: The objective of this study was to investigate the factors affecting the duration of continuous breastfeeding of infants within 2 years of age in China and explore intervention strategies to promote breastfeeding duration. A self-made electronic questionnaire was used to collect data on breastfeeding duration and influencing factors from individual, family, and social support levels. The findings showed that breastfeeding duration in China is generally short, with a low proportion of mothers breastfeeding until the recommended age of 2 years and above. Multiple factors at different levels influence breastfeeding duration. It is suggested to improve the situation through health education, system security improvement, and enhanced social support.
Article
Allergy
Simon de Lusignan, Helen Alexander, Conor Broderick, John Dennis, Andrew McGovern, Claire Feeney, Carsten Flohr
Summary: There is an increased risk of developing autoimmune conditions among individuals newly diagnosed with AD, especially those with more severe AD.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2022)
Article
Multidisciplinary Sciences
Seung Won Lee, Jiwon Park, Hayeon Kim, Yong Woo Jung, Yoo Sang Baek, Yejee Lim, Kyungim Kim
Summary: This nationwide matched cohort study found that atopic dermatitis (AD) is associated with an increased risk of gastroesophageal reflux disease (GERD). Appropriate management should be considered in adults with AD to prevent GERD.
Article
Dermatology
Alexa Magyari, Morgan Ye, David J. Margolis, Charles E. McCulloch, Steven R. Cummings, Kristine Yaffe, Sinead M. Langan, Katrina Abuabara
Summary: The study found that active atopic eczema was associated with a 27% increased risk of incident dementia during follow-up, and the risk increased with the severity of eczema.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2022)
Article
Neurosciences
Yoshihiro Miyake, Keiko Tanaka, Hitomi Okubo, Satoshi Sasaki, Akiko Tokinobu, Masashi Arakawa
Summary: The study suggests that higher maternal magnesium intake during pregnancy is inversely associated with hyperactivity problems in Japanese children, while there were no evident associations observed between maternal intake of other metal elements and childhood behavioral problems.
NUTRITIONAL NEUROSCIENCE
(2022)
Article
Pediatrics
Maoka Yamada, Keiko Tanaka, Masashi Arakawa, Yoshihiro Miyake
Summary: Our study found an association between maternal depression during pregnancy and postpartum and childhood behavioral problems. Specifically, maternal depressive symptoms during these periods were linked to emotional symptoms, conduct problems, hyperactivity, and peer problems in children, highlighting the impact of perinatal maternal depression on childhood development.
PEDIATRIC RESEARCH
(2022)
Article
Gastroenterology & Hepatology
Atsushi Nishikawa, Keiko Tanaka, Yoshihiro Miyake, Chisato Nagata, Shinya Furukawa, Akira Andoh, Tetsuji Yokoyama, Naoki Yoshimura, Kenichiro Mori, Tomoyuki Ninomiya, Yasunori Yamamoto, Eiji Takeshita, Yoshio Ikeda, Mitsuru Saito, Katsuhisa Ohashi, Hirotsugu Imaeda, Kazuki Kakimoto, Kazuhide Higuchi, Hiroaki Nunoi, Yuji Mizukami, Seiyuu Suzuki, Sakiko Hiraoka, Hiroyuki Okada, Keitarou Kawasaki, Masaaki Higashiyama, Ryota Hokari, Hiromasa Miura, Teruki Miyake, Teru Kumagi, Hiromasa Kato, Naohito Hato, Koji Sayama, Yoichi Hiasa
Summary: This Japanese case-control study found that ever smoking was associated with an increased risk of ulcerative colitis (UC), especially among former smokers. However, no significant association was observed between current smoking and UC risk. Passive smoking exposure at home was also found to be significantly associated with an increased risk of UC.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Endocrinology & Metabolism
Hiroshi Kumon, Yoshihiro Miyake, Yuta Yoshino, Jun-ichi Iga, Keiko Tanaka, Hidenori Senba, Eizen Kimura, Takashi Higaki, Bunzo Matsuura, Ryuichi Kawamoto, Shu-ichi Ueno
Summary: This is the first study to show significant associations between AGXT2 SNP rs37369, the CTA haplotype, and the CCA haplotype and DM. No interaction with regard to the risk of DM was observed between rs37369 and smoking.
CANADIAN JOURNAL OF DIABETES
(2022)
Article
Biochemistry & Molecular Biology
Yoshihiro Miyake, Keiko Tanaka, Chisato Nagata, Shinya Furukawa, Akira Andoh, Tetsuji Yokoyama, Naoki Yoshimura, Kenichiro Mori, Tomoyuki Ninomiya, Yasunori Yamamoto, Eiji Takeshita, Yoshio Ikeda, Mitsuru Saito, Katsuhisa Ohashi, Hirotsugu Imaeda, Kazuki Kakimoto, Kazuhide Higuchi, Hiroaki Nunoi, Yuji Mizukami, Seiyuu Suzuki, Sakiko Hiraoka, Hiroyuki Okada, Keitarou Kawasaki, Masaaki Higashiyama, Ryota Hokari, Hiromasa Miura, Teruki Miyake, Teru Kumagi, Hiromasa Kato, Naohito Hato, Koji Sayama, Yoichi Hiasa
Summary: The IL12B gene SNP rs6887695 is significantly associated with the risk of UC, with individuals carrying the GG genotype having an increased risk. The influence of alcohol consumption on UC risk may depend on rs6887695.
Article
Nutrition & Dietetics
Yoshihiro Miyake, Keiko Tanaka, Hitomi Okubo, Satoshi Sasaki, Masashi Arakawa
Summary: This study in Japan explored the association between tryptophan intake and depressive symptoms during pregnancy. The results indicated that higher tryptophan intake was independently associated with a lower prevalence of depressive symptoms during pregnancy.
EUROPEAN JOURNAL OF NUTRITION
(2022)
Article
Public, Environmental & Occupational Health
Yoshihiro Miyake, Keiko Tanaka, Hitomi Okubo, Satoshi Sasaki, Masashi Arakawa
Summary: Limited and inconsistent evidence exists regarding the relationship between maternal calcium intake during pregnancy and childhood blood pressure. This prebirth cohort study in Japanese children aged 6 years found that higher maternal calcium intake may be associated with a decrease in diastolic blood pressure, but not systolic blood pressure.
ANNALS OF EPIDEMIOLOGY
(2022)
Article
Environmental Sciences
Akiko Tokinobu, Keiko Tanaka, Masashi Arakawa, Yoshihiro Miyake
Summary: This study investigated the association between pre- and postnatal maternal hair dye use and the risk of wheeze and asthma in 5-year-old Japanese children. The study found that prenatal and postnatal maternal hair dye use was associated with an increased risk of wheeze and asthma in children. Children exposed to maternal hair dye use both before and after birth had a higher risk of wheeze and asthma.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH
(2022)
Article
Allergy
Maoka Yamada, Keiko Tanaka, Chisato Nagata, Masashi Arakawa, Yoshihiro Miyake
Summary: Prenatal and postnatal smoking exposure is associated with an increased prevalence of wheeze and asthma among 3-year-old Japanese girls, but not boys. Girls exposed to both prenatal maternal smoking and postnatal household smoking have a significantly higher prevalence of wheeze and physician-diagnosed asthma. Significant interactions between sex and smoking exposure affecting wheeze and asthma were found.
Article
Peripheral Vascular Disease
Yoshihiro Miyake, Keiko Tanaka, Chisato Nagata, Hidenori Senba, Yasuko Hasebe, Toyohisa Miyata, Takashi Higaki, Eizen Kimura, Bunzo Matsuura, Ryuichi Kawamoto
Summary: In women, higher intake of fish and n-3 and n-6 polyunsaturated fatty acids may be associated with a lower prevalence of carotid wall thickening and a decrease in maximum carotid intima-media thickness. However, no significant associations were found between intake of fish and other fatty acids and carotid wall thickening or maximum carotid intima-media thickness in men.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
(2023)
Article
Gastroenterology & Hepatology
Keiko Tanaka, Hitomi Okubo, Yoshihiro Miyake, Chisato Nagata, Shinya Furukawa, Akira Andoh, Tetsuji Yokoyama, Naoki Yoshimura, Kenichiro Mori, Tomoyuki Ninomiya, Yasunori Yamamoto, Eiji Takeshita, Yoshio Ikeda, Mitsuru Saito, Katsuhisa Ohashi, Hirotsugu Imaeda, Kazuki Kakimoto, Kazuhide Higuchi, Hiroaki Nunoi, Yuji Mizukami, Seiyuu Suzuki, Sakiko Hiraoka, Hiroyuki Okada, Keitarou Kawasaki, Masaaki Higashiyama, Ryota Hokari, Hiromasa Miura, Teruki Miyake, Teru Kumagi, Hiromasa Kato, Naohito Hato, Koji Sayama, Yoichi Hiasa
Summary: This Japanese case-control study found that consumption of coffee and caffeine is associated with a reduced risk of ulcerative colitis (UC), while consumption of chocolate snacks is associated with an increased risk of UC.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Rheumatology
Yusuke Kashiwado, Chikako Kiyohara, Yasutaka Kimoto, Shuji Nagano, Takuya Sawabe, Kensuke Oryoji, Shinichi Mizuki, Hiroaki Nishizaka, Seiji Yoshizawa, Shigeru Yoshizawa, Tomomi Tsuru, Yasushi Inoue, Naoyasu Ueda, Shun-ichiro Ota, Yasuo Suenaga, Tomoya Miyamura, Yoshifumi Tada, Hiroaki Niiro, Koichi Akashi, Takahiko Horiuchi
Summary: Discontinuation of biologic therapy after hospitalization for infections may lead to flares in rheumatoid arthritis. Continuing biologic therapy reduces the risk of rheumatoid arthritis flares, especially in patients without immunodeficiency.
ARTHRITIS RESEARCH & THERAPY
(2022)
