期刊
TRANSPLANT INTERNATIONAL
卷 28, 期 6, 页码 665-676出版社
WILEY
DOI: 10.1111/tri.12530
关键词
delayed graft function; donation after brain death; donation after circulatory death; expanded criteria donors; extended criteria donors; graft quality; history of machine perfusion; hypothermic machine perfusion; kidney transplantation; organ preservation; perfusate biomarkers; renal resistance; viability assessment
Hypothermic machine perfusion (HMP) of kidneys is a long-established alternative to static cold storage and has been suggested to be a better preservation method. Today, as our deceased donor profile continues to change towards higher-risk kidneys of lower quality, we are confronted with the limits of cold storage. Interest in HMP as a preservation technique is on the rise. Furthermore, HMP also creates a window of opportunity during which to assess the viability and quality of the graft before transplantation. The technology might also provide a platform during which the graft could be actively repaired, making it particularly attractive for higher-risk kidneys. We review the current evidence on HMP in kidney transplantation and provide an outlook for the use of the technology in the years to come.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据