期刊
PARKINSONISM & RELATED DISORDERS
卷 15, 期 1, 页码 24-29出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.parkreldis.2008.02.007
关键词
Vascular; Parkinson's disease; Intimomedial thickness; Stroke; Pulsatility index; Cognitive
资金
- [MSM0021622404]
To study the impact of brain vessel pathology on the clinical status of Parkinson's disease (PD), in 57 consecutive patients the clinical and neuropsychological data were compared with clinical MRI signs of vascular impairment and with the ultrasound brain vessel investigations. There was a significant correlation between clinical and cognitive status and intimomedial thickness, which is an indicator of large vessel impairment. Cognitive status was significantly related to the pulsatility index (an indicator of small vessel impairment). This study provides evidence that subclinical vascular pathology could influence the clinical status by contributing to motor and cognitive dysfunction in PD. (C) 2008 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据