期刊
PARKINSONISM & RELATED DISORDERS
卷 14, 期 6, 页码 501-504出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.parkreldis.2007.11.005
关键词
Parkinson disease; surface EMG; tremor; CM/PF complex; DBS
Aim of this study was to investigate whether Deep Brain Stimulation (DBS) of the Centre Median Nucleus/Parafascicular (CM/PF) Complex is useful in reducing extrapyramidal symptoms in advanced Parkinson's Disease (PD) patients. In particular, we compared the action of CM/PF and subthalamic nucleus (STN) DBS on resting hand tremor using EMG surface of ulnar and radial right-hand muscles. Our results show that C/M DBS is very effective in reducing tremor, indicating this complex as a new target in advanced PD patients. (C) 2008 Elsevier Ltd. All rights reserved.
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