Article
Microbiology
Niels Arni Arnason, Freyr Johannsson, Ragna Landro, Bjorn Hardarsson, Sveinn Gudmundsson, Aina-Mari Lian, Janne Reseland, Ottar Rolfsson, Olafur E. Sigurjonsson
Summary: This study investigated the effect of pathogen inactivation on the release of proteins in stored platelets. The results showed that the majority of proteins increased in concentration during storage, but some proteins had significantly different concentrations between the pathogen inactivated group and the control group. Additionally, a subset of proteins displayed a decrease in concentration related to pathogen inactivation. The study found that pathogen inactivation had limited effect on protein concentration in stored platelets.
Article
Chemistry, Physical
Chunjian Tan, Shaogang Wang, Huiru Yang, Qianming Huang, Shizhen Li, Xu Liu, Huaiyu Ye, Guoqi Zhang
Summary: Short-wave ultraviolet (UVC) irradiation is commonly used for viral inactivation due to its ability to damage genetic material. However, the molecular mechanism of UVC inactivation on viruses remains unknown. In this study, quantum chemical calculations were used to investigate the response mechanism of genome materials to UVC light, focusing on the spectral properties of nucleotides and the reaction rate of uracil molecules with and without UVC irradiation. The results indicate that nucleotide reactions are photochemical processes and almost cannot occur without UVC irradiation.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Article
Engineering, Environmental
Shotaro Torii, Marie-Helene Corre, Fuminari Miura, Masae Itamochi, Kei Haga, Kazuhiko Katayama, Hiroyuki Katayama, Tamar Kohn
Summary: The study examined the inactivation kinetics of different enterovirus variants by free chlorine and UV irradiation, revealing that the inactivation mechanisms of free chlorine are genotype- and genogroup-dependent, while UV inactivation mainly depends on genomic size and composition. The distribution of inactivation rate constants and the abundance of each genotype are crucial parameters in accurately predicting the overall inactivation of an enterovirus population by free chlorine.
Article
Hematology
Esam I. Azhar, Salwa I. Hindawi, Sherif A. El-Kafrawy, Ahmed M. Hassan, Ahmed M. Tolah, Thamir A. Alandijany, Leena H. Bajrai, Ghazi A. Damanhouri
Summary: The study aimed to evaluate the efficacy of amotosalen/UVA light treatment in inactivating SARS-CoV-2 in human plasma. The results showed complete inactivation of infectious SARS-CoV-2 particles, reducing the potential risk of transfusion-related transmission.
Article
Infectious Diseases
Breno Lima de Almeida, Marta Giovanetti, Joao Vitor Oliveira, Tereza Cristina Xavier Carvalho, Eduardo Manoel Figueiredo, Rosana Pellegrini, Juan Ignacio Calcagno, Marcia Weber Carneiro, Juliana M. G. C. de Oliveira, Adriana Virginia Barros Faical, Iluska Andrade Agra, Cristina Salles, Emilia Katiane Embirucu de Araujo Leao, Rita Lucena, Angelina X. Acosta, Luiz Carlos Junior Alcantara, Isadora Cristina de Siqueira
Summary: This study investigated fourteen asymptomatic normocephalic newborns with confirmed congenital Zika infection. All newborns tested positive for Zika virus on reverse transcriptase polymerase chain reaction. Phylogenetic analysis of one child's ZIKV-specific NS5 gene fragment sequencing revealed that the isolated strain belonged to the Asian genotype and clustered closely with sequences previously isolated in the northeast and northern regions of Brazil.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Review
Engineering, Environmental
Nicolas Augsburger, Andri Taruna Rachmadi, Noor Zaouri, Yunho Lee, Pei-Ying Hong
Summary: The study found that Caliciviridae, Picornaviridae family, and rotavirus are more sensitive to UV radiation compared to adenoviruses. Using MP-UV is a more promising strategy than LP-UV, and UV-LED technology shows potential. However, more research is needed to evaluate the efficacy of UV-LEDs and UV-AOP in inactivating enteric viruses.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Hosoon Choi, Piyali Chatterjee, Eric Lichtfouse, Julie A. Martel, Munok Hwang, Chetan Jinadatha, Virender K. Sharma
Summary: This paper reviews the currently used disinfection strategies to control SARS-CoV-2 at healthcare facilities, including chemical disinfectants and advanced disinfection techniques.
ENVIRONMENTAL CHEMISTRY LETTERS
(2021)
Article
Environmental Sciences
Arijana Filipic, David Dobnik, Ion Gutierrez-Aguirre, Maja Ravnikar, Tamara Kosir, Spela Baebler, Alja Stern, Bojana Zegura, Martin Petkovsek, Matevz Dular, Miran Mozetic, Rok Zaplotnik, Gregor Primc
Summary: Water scarcity is a significant challenge we face today, and the inactivation of waterborne viruses is an important concern. This study successfully developed a device combining plasma and supercavitation, which demonstrated high efficiency in water decontamination. The device is environmentally friendly and provides contamination-free and safe water resources.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Multidisciplinary Sciences
Patricia Nobrega Gomes, Beatriz Aguiar do Amaral, Isabelita Duarte Azevedo, Haline Cunha de Medeiros Maia, Nivia Maria Rodrigues Arrais, Kenio Costa de Lima
Summary: This study analyzed the association between congenital Zika syndrome (CZS) and dental alterations in children with microcephaly. The results showed that although CZS was associated with microcephaly, it did not affect the eruption sequence or enamel development of primary teeth.
Article
Environmental Sciences
Kotaro Takamure, Yasuaki Sakamoto, Yasumasa Iwatani, Hiroshi Amano, Tetsuya Yagi, Tomomi Uchiyama
Summary: A general-purpose virus inactivation unit using deep ultraviolet (DUV) LEDs emitting DUV rays with a wavelength of 280 nm was developed. Numerical simulations were used to investigate the flow characteristics of air and virus particles inside the unit. The experiments demonstrated that DUV-LED irradiation reduced the concentration of SARS-CoV-2 RNA to 60% and effectively inactivated the virus within the unit.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Biochemistry & Molecular Biology
Yunxia He, Weili Yu, Lucheng Xiao, Lijuan Shen, Jinming Qi, Tao Hu
Summary: The study improved the immunogenicity of EDIII by covalently conjugating it with CRM197, 8-arm PEG, and mannan, resulting in high levels of EDIII-specific antibody titers and secretion of Th1 and Th2 cytokines in a mouse model.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Environmental Sciences
Jile Fu, Yiyi Xu, Eric J. Arts, Zhengyu Bai, Zhongwei Chen, Ying Zheng
Summary: The transmission of viral infections via aerosol is a serious threat to public health, and non-thermal plasma technology has gained interest for its highly effective disinfection and flexible operation.
Article
Food Science & Technology
Branko Velebit, Lazar Milojevic, Tatjana Baltic, Nevena Grkovic, Sanjay Gummalla, Marina Velebit, Ines Skoko, Sandra Mojsova, Predrag Putnik
Summary: This study investigates the effectiveness of cold atmospheric plasma (CAP) in inactivating viruses on raspberries. CAP treatment successfully reduces the viral load in a short period of time without affecting the fruit quality. This provides an environmentally-friendly and cost-effective method for microbial decontamination in the raspberry industry.
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES
(2022)
Article
Biochemistry & Molecular Biology
Daniel M. Mrochen, Lea Miebach, Henry Skowski, Robert Bansemer, Chiara A. Drechsler, Ulfilas Hofmanna, Manuel Hein, Uwe Mamat, Torsten Gerling, Ulrich Schaible, Thomas Von Woedtke, Sander Bekeschus
Summary: Plasma medicine is a developing field that utilizes cold physical plasma for therapeutic purposes. This technology has been approved for treating chronic wounds and skin infections, and has shown potential for virus inactivation. The antimicrobial activity of cold plasma is linked to its generation of reactive oxygen and nitrogen species (ROS). In studies using a micro plasma jet, it was found that plasma exposure reduced the number of infected cells and showed cytotoxic effects. Direct contact with the target maximized the activity, and antioxidant pretreatment reduced but did not eliminate the effects, suggesting non-ROS-related mechanisms of antiviral activity.
FREE RADICAL BIOLOGY AND MEDICINE
(2022)
Article
Microbiology
Arijana Filipic, David Dobnik, Magda Tusek Znidaric, Bojana Zegura, Alja Stern, Gregor Primc, Miran Mozetic, Maja Ravnikar, Jana Zel, Ion Gutierrez Aguirre
Summary: Water scarcity poses a major threat to human survival and quality of life, leading to an increased risk of infections from waterborne viruses. Cold atmospheric plasma (CAP) is emerging as an efficient, safe, and sustainable alternative for waterborne virus inactivation. In this study, CAP treatment successfully inactivated a resilient waterborne virus, PMMoV, without introducing any cytotoxic or genotoxic effects, showing promise for further examination as an alternative for treating potable and irrigation waters, as well as other sources of water, with a focus on inactivating various viruses, including enteric viruses.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Infectious Diseases
Yoann Teissier, Richard Paul, Maite Aubry, Xavier Rodo, Carlos Dommar, Henrik Salje, Anavaj Sakuntabhai, Bernard Cazelles, Van-Mai Cao-Lormeau
PLOS NEGLECTED TROPICAL DISEASES
(2020)
Article
Biology
Alasdair D. Henderson, Maite Aubry, Mike Kama, Jessica Vanhomwegen, Anita Teissier, Teheipuaura Mariteragi-Helle, Tuterarii Paoaafaite, Yoann Teissier, Jean-Claude Manuguerra, John Edmunds, Jimmy Whitworth, Conall H. Watson, Colleen L. Lau, Van-Mai Cao-Lormeau, Adam J. Kucharski
Letter
Medicine, General & Internal
Alice Panchaud, Guillaume Favre, Leo Pomar, Manon Vouga, Karoline Aebi-Popp, David Baud
Letter
Infectious Diseases
David Baud, Karin Nielsen-Saines, Xiaolong Qi, Didier Musso, Leo Pomar, Guillaume Favre
LANCET INFECTIOUS DISEASES
(2020)
Letter
Infectious Diseases
David Baud, Xiaolong Qi, Karin Nielsen-Saines, Didier Musso, Leo Pomar, Guillaume Favre
LANCET INFECTIOUS DISEASES
(2020)
Article
Public, Environmental & Occupational Health
Fatou Kine Fall, Maureen Laroche, Herve Bossin, Didier Musso, Philippe Parola
Summary: This study successfully identified mosquito colonies from French Polynesia using MALDI-TOF MS technology, achieving 100% correct identification at the species level. The technique also allowed differentiation between male and female mosquitoes, as well as specific identification of female mosquito colonies of the same species but different geographic origin.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2021)
Article
Multidisciplinary Sciences
Maite Aubry, Iotefa Teiti, Anita Teissier, Vaea Richard, Teheipuaura Mariteragi-Helle, Kiyojiken Chung, Farah Deen, Tuterarii Paoaafaite, Van-Mai Cao-Lormeau
Summary: In French Polynesia, measures were implemented to control and prevent the spread of COVID-19, including requiring travelers to undergo nucleic acid testing, screening through self-collection and pooling methods, and detecting virus variants.
Letter
Public, Environmental & Occupational Health
Van-Mai Cao-Lormeau, Iotefa Teiti, Anita Teissier, Vaea Richard, Maite Aubry
TRAVEL MEDICINE AND INFECTIOUS DISEASE
(2021)
Article
Infectious Diseases
Claude Flamand, Christelle Alves Sarmento, Antoine Enfissi, Sarah Bailly, Emmanuel Beillard, Melanie Gaillet, Celine Michaud, Veronique Servas, Nathalie Clement, Anais Perilhou, Thierry Carage, Didier Musso, Jean-Francois Carod, Stephanie Eustache, Celine Tourbillon, Elodie Boizon, Samantha James, Felix Djossou, Henrik Salje, Simon Cauchemez, Dominique Rousset
Summary: During the first epidemic wave in the first half of 2020, Latin America conducted only a few seroprevalence studies, showing an overall seroprevalence of 15.4% in a cross-sectional survey with 480 participants from 4 medical laboratories or 5 health centers. The results indicated high levels of infection across the territory but a low number of resulting deaths, possibly due to the young population structure in French Guiana.
PLOS NEGLECTED TROPICAL DISEASES
(2021)
Editorial Material
Virology
Didier Musso, Dominique Rousset, Christophe Peyrefitte
Letter
Medicine, General & Internal
Pradip Dashraath, Karin Nielsen-Saines, Citra Mattar, Didier Musso, Paul Tambyah, David Baud
Article
Medicine, General & Internal
Adam J. Kucharski, Kiyojiken Chung, Maite Aubry, Iotefa Teiti, Anita Teissier, Vaea Richard, Timothy W. Russell, Raphaelle Bos, Sophie Olivier, Van-Mai Cao-Lormeau, Philippa C. Dodd
Summary: The study shows that analyzing COVID-19 testing data from international arrivals can provide insights into the prevalence of the virus in different countries, and this method can serve as a scalable and accurate indicator of global infections during future pandemics.