Article
Parasitology
Christopher Charles Evans, Dorothy Normile, Sheryl Gamble, Frank Guerino, Michael T. T. Dzimianski, Andrew Riddell Moorhead
Summary: This study investigates the effects of oral medication Fluralaner (Bravecto) on the major vector of canine heartworm, Aedes aegypti mosquitoes. The results show that mosquitoes fed with blood from dogs treated with Fluralaner experience a significant reduction in survival and reproductive ability, supporting the potential for reducing heartworm transmission by directly killing the vector and indirectly reducing the local vector population.
PARASITES & VECTORS
(2023)
Article
Parasitology
Melissa Petersen, Riaan Maree, Alta Viljoen, Julian E. E. Liebenberg, Frank Guerino
Summary: In two 90-day studies, it was found that a single administration of fluralaner chewable tablets at the minimum recommended dose rate of 25 mg/kg was 100% effective in eliminating H.longicornis ticks from dogs. This efficacy was maintained for 90 days following treatment.
PARASITES & VECTORS
(2023)
Article
Parasitology
Bernadete Dantas Queiroga Tamyres, Cardoso Pereira Gomez Luanderson, Eduardo Rodrigues de Sena, Wilo Victor dos Santos, Rafael Pontes Ferreira Henrique, Vicente Toscano de Araujo-Neto, Andressa Noronha Barbosa-Silva, Carlos Ramon do Nascimento Brito, Romeika Karla dos Reis Lima, Joao Ciro Fagundes-Neto, Lucia Maria da Cunha Galvao, Henrique Rocha de Medeiros, Antonia Claudia Jacome da Camara, Manuela Sales Lima Nascimento, Renata Antonaci Gama, Paulo Marcos Matta Guedes
Summary: The study evaluated the insecticidal effect of fluralaner on Triatoma brasiliensis after feeding on treated dogs, showing 100% mortality within 7 months post-treatment, declining to 0% after 12 months. This indicates a potential long-term approach to control vector transmission of Chagas disease, especially in endemic areas.
PARASITES & VECTORS
(2021)
Article
Parasitology
Kathryn Duncan, Anne W. Barrett, Susan E. Little, Kellee D. Sundstrom, Frank Guerino
Summary: Treating heartworm-infected dogs with fluralaner limits the survival of infected mosquitoes, reducing the transmission of D. immitis.
PARASITES & VECTORS
(2023)
Article
Parasitology
Nadja Rohdich, Leon Meyer, Frank Guerino
Summary: This study aimed to evaluate the efficacy of a new fluralaner formulation in treating generalized demodicosis. The findings showed that three consecutive monthly oral treatments with fluralaner effectively eliminated mites and improved the condition of the dogs diagnosed with this disease.
PARASITES & VECTORS
(2022)
Article
Parasitology
Melissa Petersen, Riaan Maree, Henda Pretorius, Julian E. Liebenberg, Frank Guerino
Summary: Two 90-day studies confirmed the efficacy of two fluralaner formulations in eliminating H. longicornis ticks from cats. The treatments were found to be 100% effective on Day 2 and maintained an efficacy of >95% to 100% for 90 days. Fluralaner is therefore a preferred treatment for protecting cats against this invasive tick species.
PARASITES & VECTORS
(2023)
Article
Parasitology
Petr Fisara, Frank Guerino
Summary: A study has found that a single subcutaneous treatment can provide persistent efficacy against fleas and brown dog ticks for 12 months. This year-round effective treatment has the potential to improve owner compliance and enhance canine health.
PARASITES & VECTORS
(2023)
Article
Parasitology
Petr Fisara, Frank Guerino
Summary: This study investigated the efficacy of an injectable suspension of fluralaner against Ixodes holocyclus infestations in dogs. The results showed that a single treatment with this suspension provided protection for up to 13 months, reducing the risk of tick-induced paralysis in dogs.
PARASITES & VECTORS
(2023)
Article
Parasitology
Marcelo Bahia Labruna, Juliana Salomao Doretto, Olivia Carmen de Araujo Nascimento, Francisco Bonomi Barufi, Simone Cristina Rosa, Germana Vizzotto Osowski, Jason Drake, Rob Armstrong
Summary: This study evaluated the effect of either external or systemic canine treatment on Rhipicephalus sanguineus populations in premises. The results showed that systemic treatment was more effective than external treatment in eliminating tick infestations.
PARASITES & VECTORS
(2023)
Article
Infectious Diseases
Katharine Costa dos Santos, Rafael Marin Chiummo, Anja Regina Heckeroth, Eva Zschiesche, Paula Elisa Brandao Guedes, Tatiani Vitor Harvey, Anderson Vieira de Jesus, Anaia da Paixao Seva, Joana Thaisa Santos de Oliveira, Zelina dos Santos Freire, Juergen Krucken, Fernando de Almeida Borges, Georg Von Samson-Himmelstjerna, Renata Santiago Alberto Carlos
Summary: This study evaluated the therapeutic and residual efficacy of fluralaner for treating tungiasis in dogs. The results showed that a single oral administration of fluralaner is effective in treating and achieving long-lasting prevention for tungiasis in dogs.
PLOS NEGLECTED TROPICAL DISEASES
(2022)
Article
Parasitology
Rafael Chiummo, Eva Zschiesche, Balazs Capari, Robert Farkas, Mathieu Chiquet, Dhimiter Rapti, Rezart Postoli, Alain Audry, Michael Leschnik
Summary: This study demonstrated that the use of fluralaner chewable tablets effectively prevents the transmission of Babesia canis in dogs under natural conditions, with a 100% efficacy rate.
PARASITES & VECTORS
(2023)
Article
Parasitology
Katharina Raue, Nadja Rohdich, Daniela Hauck, Eva Zschiesche, Simone Morelli, Donato Traversa, Angela Di Cesare, Rainer K. A. Roepke, Christina Strube
Summary: The preventive efficacy of Bravecto (R) Plus spot-on solution against feline lungworm Aelurostrongylus abstrusus was evaluated in a laboratory study, showing that a single application of the solution reliably prevents cat aelurostrongylosis for at least 12 weeks.
PARASITES & VECTORS
(2021)
Article
Parasitology
Gioia Bongiorno, Leon Meyer, Alec Evans, Nouha Lekouch, Padraig Doherty, Rafael Chiummo, Luigi Gradoni
Summary: A single oral administration of fluralaner to dogs under laboratory conditions results in strong and reproducible insecticidal efficacy against P. perniciosus for at least 8 weeks.
PARASITES & VECTORS
(2022)
Article
Pediatrics
Bernhard Kienesberger, Christoph Arneitz, Vanessa Wolfschluckner, Christina Flucher, Peter Spitzer, Georg Singer, Christoph Castellani, Holger Till, Johannes Schalamon
Summary: This study found that educating primary school children can effectively reduce the severity of dog bite injuries. The research showed that after implementing prevention measures, the severity of injuries significantly decreased, and the number of patients requiring hospital treatment also declined.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Article
Parasitology
Ricardo Esteban Gurtler, Mariano Alberto Laino, Alejandra Alvedro, Gustavo Fabian Enriquez, Natalia Paula Macchiaverna, Maria Sol Gaspe, Marta Victoria Cardinal
Summary: Fluralaner had a significant impact on the abundance and infection rate of Triatoma infestans, making it an important intervention for interrupting the transmission of Trypanosoma cruzi.
PARASITES & VECTORS
(2022)