期刊
PARASITE
卷 19, 期 2, 页码 101-115出版社
EDP SCIENCES S A
DOI: 10.1051/parasite/2012192101
关键词
cancer; parasite; Clonorchis; Cryptosporidium; Opisthorchis; protists; Schistosoma; infection
类别
资金
- French Ministry of Research [EA4547 Universite de Lille 2]
- French National Research Agency [ANR-09-ALIA-009 ProtoFood, ANR-10-ALIA-004 Fish-Parasites]
- Consejo de Desarrollo Cientifico y Humanistic of the Universidad Central de Venezuela
The International Agency for Research on Cancer (IARC) identifies ten infectious agents (viruses, bacteria, parasites) able to induce cancer disease in humans. Among parasites, a carcinogenic role is currently recognized to the digenetic trematodes Schistosoma haematobium, leading to bladder cancer, and to Clonorchis sinensis or Opisthorchis viverrini, which cause cholangiocarcinoma. Furthermore, several reports suspected the potential association of other parasitic infections (due to Protozoan or Metazoan parasites) with the development of neoplastic changes in the host tissues. The present work shortly reviewed available data on the involvement of parasites in neoplastic processes in humans or animals, and especially focused on the carcinogenic power of Cryptosporidium parvum infection. On the whole, infection seems to play a crucial role in the etiology of cancer.
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