Immunoregulation in human American leishmaniasis: balancing pathology and protection

Immunological and Genetic Evidence for a Crucial Role of IL-10 in Cutaneous Lesions in Humans Infected with Leishmania braziliensis

(2014) Adnene Salhi et al.   JOURNAL OF IMMUNOLOGY

CD8 T Cell Exhaustion in Human Visceral Leishmaniasis

(2013) Shalini Gautam et al.   JOURNAL OF INFECTIOUS DISEASES

CD8+ Granzyme B+–Mediated Tissue Injury vs. CD4+IFNγ+–Mediated Parasite Killing in Human Cutaneous Leishmaniasis

(2013) Claire da Silva Santos et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Common variants in the HLA-DRB1–HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis

(2013) Michaela Fakiola et al.   NATURE GENETICS

Macrophages participate in host protection and the disease pathology associated with Leishmania braziliensisinfection

(2012) Angela Giudice et al.   BMC INFECTIOUS DISEASES

Association between an Emerging Disseminated form of Leishmaniasis and Leishmania (Viannia) braziliensis Strain Polymorphisms

(2012) A. Queiroz et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Loss of TNF Signaling Facilitates the Development of a Novel Ly-6Clow Macrophage Population Permissive for Leishmania major Infection

(2012) P. D. Fromm et al.   JOURNAL OF IMMUNOLOGY

High Interleukin 17 Expression Is Correlated With Better Cardiac Function in Human Chagas Disease

(2012) Luisa M. D. Magalhães et al.   JOURNAL OF INFECTIOUS DISEASES

Cytokines and visceral leishmaniasis: a comparison of plasma cytokine profiles between the clinical forms of visceral leishmaniasis

(2012) Alinne Silva Andrade Costa et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Immunoregulatory profile of monocytes from cutaneous leishmaniasis patients and association with lesion size

(2012) É. L. M. Vieira et al.   PARASITE IMMUNOLOGY

Regulatory T Cells Suppress T Cell Activation at the Pathologic Site of Human Visceral Leishmaniasis

(2012) Ambak K. Rai et al.   PLoS One

Protective and pathologic immune responses in human tegumentary leishmaniasis

(2012) Lucas P. Carvalho et al.   Frontiers in Immunology

Lesion Size Correlates with Leishmania Antigen-Stimulated TNF-Levels in Human Cutaneous Leishmaniasis

(2011) Fabiano Oliveira et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

CD3+CD4−CD8− (double negative) T cells: Saviours or villains of the immune response?

(2011) Fulvio D’Acquisto et al.   BIOCHEMICAL PHARMACOLOGY

CD4+ T cells defined by their Vβ T cell receptor expression are associated with immunoregulatory profiles and lesion size in human leishmaniasis

(2011) T. S. L. Keesen et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Visceral leishmaniasis: immunology and prospects for a vaccine

(2011) P.M. Kaye et al.   CLINICAL MICROBIOLOGY AND INFECTION

Immunoregulatory and effector activities in human cutaneous and mucosal Leishmaniasis: Understanding mechanisms of pathology

(2011) Walderez O. Dutra et al.   DRUG DEVELOPMENT RESEARCH

Characterization of the immunoregulatory function of human TCR-αβ+ CD4−CD8− double-negative T cells

(2011) Simon Voelkl et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-10 Neutralization Promotes Parasite Clearance in Splenic Aspirate Cells From Patients With Visceral Leishmaniasis

(2011) Shalini Gautam et al.   JOURNAL OF INFECTIOUS DISEASES

The effects of macrophage source on the mechanism of phagocytosis and intracellular survival of Leishmania

(2011) Chia-Hung Christine Hsiao et al.   MICROBES AND INFECTION

Leishmaniasis: complexity at the host–pathogen interface

(2011) Paul Kaye et al.   NATURE REVIEWS MICROBIOLOGY

Evaluation of parasitological and immunological parameters of Leishmania chagasi infection in BALB/c mice using different doses and routes of inoculation of parasites

(2011) Dulcilene M. Oliveira et al.   PARASITOLOGY RESEARCH

Reappraisal of the immunopathogenesis of disseminated leishmaniasis: in situ and systemic immune response

(2011) Paulo R. Machado et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Human mucosal leishmaniasis: Neutrophils infiltrate areas of tissue damage that express high levels of Th17-related cytokines

(2010) Viviane S. Boaventura et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The −2518bp promoter polymorphism at CCL2/MCP1 influences susceptibility to mucosal but not localized cutaneous leishmaniasis in Brazil

(2010) Rajendranath Ramasawmy et al.   INFECTION GENETICS AND EVOLUTION

IL-17 and Regulatory Cytokines (IL-10 and IL-27) in L. braziliensis Infection

(2010) R. NOVOA et al.   PARASITE IMMUNOLOGY

Immunoactivation and immunopathogeny during active visceral leishmaniasis

(2010) Hiro Goto et al.   REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO

CD8+ T Cells as a Source of IFN-γ Production in Human Cutaneous Leishmaniasis

(2010) Mahmoud Nateghi Rostami et al.   PLoS Neglected Tropical Diseases

Genetic Admixture in Brazilians Exposed to Infection withLeishmania chagasi

(2009) Nicholas A. Ettinger et al.   ANNALS OF HUMAN GENETICS

Increased levels of IL-10, IL-12, and IFN- in patients with visceral leishmaniasis

(2009) A. Khoshdel et al.   Brazilian Journal of Infectious Diseases

Differences in human macrophage receptor usage, lysosomal fusion kinetics and survival between logarithmic and metacyclicLeishmania infantum chagasipromastigotes

(2009) Norikiyo Ueno et al.   CELLULAR MICROBIOLOGY

Neutrophils and Macrophages Cooperate in Host Resistance against Leishmania braziliensis Infection

(2009) F. O. Novais et al.   JOURNAL OF IMMUNOLOGY

Miltefosine Promotes IFN- -Dominated Anti-Leishmanial Immune Response

(2009) P. Wadhone et al.   JOURNAL OF IMMUNOLOGY

Interleukin 17 Production among Patients with American Cutaneous Leishmaniasis

(2009) Olívia Bacellar et al.   JOURNAL OF INFECTIOUS DISEASES

Recruitment of CD8+T cells expressing granzyme A is associated with lesion progression in human cutaneous leishmaniasis

(2009) D. R. FARIA et al.   PARASITE IMMUNOLOGY

Genetics and visceral leishmaniasis: of mice and man

(2009) J. M. BLACKWELL et al.   PARASITE IMMUNOLOGY

Atypical manifestations of tegumentary leishmaniasis in a transmission area of Leishmania braziliensis in the state of Bahia, Brazil

(2009) L.H. Guimarães et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

The role of host genetics in leishmaniasis

(2009) Anuratha Sakthianandeswaren et al.   TRENDS IN PARASITOLOGY

B7-H1 Blockade Increases Survival of Dysfunctional CD8+ T Cells and Confers Protection against Leishmania donovani Infections

(2009) Trupti Joshi et al.   PLoS Pathogens

Leishmania donovaniinfection down-regulates TLR2-stimulated IL-12p40 and activates IL-10 in cells of macrophage/monocytic lineage by modulating MAPK pathways through a contact-dependent mechanism

(2008) Dinesh Chandra et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Persistent parasites and immunologic memory in cutaneous leishmaniasis: implications for vaccine designs and vaccination strategies

(2008) Ifeoma Okwor et al.   IMMUNOLOGIC RESEARCH

Accelerated Control of Visceral Leishmania donovani Infection in Interleukin-6-Deficient Mice

(2008) H. W. Murray   INFECTION AND IMMUNITY

Immunoregulatory mechanisms and CD4−CD8− (double negative) T cell subpopulations in human cutaneous leishmaniasis: A balancing act between protection and pathology

(2008) Kenneth J. Gollob et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Clinical features of cutaneous and disseminated cutaneous leishmaniasis caused byLeishmania (Viannia) braziliensisin Paraty, Rio de Janeiro

(2008) Ricardo Vieira-Gonçalves et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Interactions with apoptotic but not with necrotic neutrophils increase parasite burden in human macrophages infected with Leishmania amazonensis

(2008) Lilian Afonso et al.   JOURNAL OF LEUKOCYTE BIOLOGY

In Vivo Imaging Reveals an Essential Role for Neutrophils in Leishmaniasis Transmitted by Sand Flies

(2008) N. C. Peters et al.   SCIENCE