Article
Medicine, General & Internal
Elena Sirbu, Roxana Ramona Onofrei, Simona Szasz, Monica Susan
Summary: This study aimed to assess the relationship between pain intensity, catastrophizing components, depression, and disability in patients with chronic low back pain (CLBP). The results showed that age, pain intensity, catastrophizing, and depression can predict the disability level in CLBP patients.
ARCHIVES OF MEDICAL SCIENCE
(2023)
Article
Clinical Neurology
Pingge Sun, Binkun Li, Xianli Yao, Zhiyuan Wu, Yafei Yang
Summary: Patients with chronic low back pain (CLBP) have impaired postural balance, and the extent to which pain affects postural balance in these patients is unclear.
FRONTIERS IN NEUROLOGY
(2023)
Article
Health Care Sciences & Services
Arturo Cuomo, Franco Marinangeli, Alberto Magni, Emiliano Petrucci, Alessandro Vittori, Marco Cascella
Summary: Prompt and appropriate treatment of chronic low back pain is crucial for preventing disability and reducing healthcare costs. The concept of functionality in chronic pain management is still lacking a shared definition, leading to different opinions among specialists and patients. Although there are instruments available for assessing functionality, there is no consistency in their use.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Medicine, General & Internal
Gloria Gonzalez-Medina, Veronica Perez-Cabezas, Carmen Ruiz-Molinero, Gema Chamorro-Moriana, Jose Jesus Jimenez-Rejano, Alejandro Galan-Mercant
Summary: The meta-analysis demonstrated that global postural re-education (GPR) program is effective in reducing pain and improving function in patients with persistent chronic low back pain, with strong evidence support.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Computer Science, Interdisciplinary Applications
Xiaoping Zheng, Michiel F. Reneman, Rita H. R. Schiphorst Preuper, Egbert Otten, Claudine J. C. Lamoth
Summary: This study used advanced unsupervised machine learning, Hidden semi-Markov model (HSMM), to investigate the physical activity intensity patterns in patients with chronic low back pain (CLBP). The results showed that there were differences in physical activity intensity patterns between CLBP- and CLBP + patients, with CLBP + patients engaging in longer bouts of activity.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2023)
Review
Health Care Sciences & Services
Jennifer Franks, Claire Thwaites, Meg E. Morris
Summary: Low back pain is common in the community and is associated with deficits in core muscle strength and activation. Pilates is believed to improve movement and reduce pain, but there is limited understanding of its specific effects on core muscle strength or activity.
Article
Clinical Neurology
Zeynab Alshelh, Ludovica Brusaferri, Atreyi Saha, Erin Morrissey, Paulina Knight, Minhae Kim, Yi Zhang, Jacob M. Hooker, Daniel Albrecht, Angel Torrado-Carvajal, Michael S. Placzek, Oluwaseun Akeju, Julie Price, Robert R. Edwards, Jeungchan Lee, Roberta Sclocco, Ciprian Catana, Vitaly Napadow, Marco L. Loggia
Summary: This study suggests that patients with different chronic pain conditions exhibit neuroinflammation, which is accompanied by neurophysiological changes and correlates with clinical presentation. These findings contribute to the subtyping of distinct pain syndromes and provide potential targets for precision medicine.
Review
Orthopedics
Ji Ma, Teng Zhang, Yapeng He, Xin Li, Haoyang Chen, Qian Zhao
Summary: Aquatic physical therapy has been shown to benefit patients with chronic low back pain by reducing pain intensity, improving quality of life, and reducing disability. However, more high-quality studies are needed to verify these effects.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Medicine, General & Internal
Masoud Mirmoezzi, Khadijeh Irandoust, Cyrine H'mida, Morteza Taheri, Khaled Trabelsi, Achraf Ammar, Nesa Paryab, Pantelis T. Nikolaidis, Beat Knechtle, Hamdi Chtourou
Summary: The study found that symptoms of NSLBP improved after 10 sessions of hydrotherapy program based on McKenzie and Williams therapy, with NPRS, RMDQ, and SLRT scores in the hydrotherapy group showing improvement compared to baseline and the control group (p <= 0.001), and no difference in treatment variables between the 10th and 20th session (p > 0.05).
IRISH JOURNAL OF MEDICAL SCIENCE
(2021)
Article
Health Care Sciences & Services
Dalia Alimam, Ahmed Alhowimel, Faris Alodaibi, Mazyad Alotaibi, Hosam Alzahrani, Nouf Almutairi, Ali Alqahtani, Lolwah Alrashed Alhumaid, Andrew Leaver, Martin Mackey
Summary: In this study, the Pain Behavioral Scale (PaBS) was used to assess the pain behavior of patients with chronic lower back pain. The results showed that changes in PaBS scores were significantly correlated with changes in MODI, FABQ, and PCS, supporting its convergent validity. According to the severity of pain behavior, PaBS can help identify high-risk and low-risk groups in clinical assessment.
Article
Clinical Neurology
Christy Tomkins-Lane, Ruopeng Sun, Amir Muaremi, Patricia Zheng, Manoj Mohan, Ma Agnes Ith, Matthew Smuck
Summary: This study objectively characterized the daily physical activity of individuals with low back pain (LBP) using accelerometers and identified specific activity thresholds related to LBP. The findings showed that sedentary and light activity ranges were significantly different between the LBP group and healthy controls, while moderate to vigorous physical activity was not discriminative. These results can contribute to the development of LBP-specific physical activity interventions.
Article
Orthopedics
Shiro Imagama, Hideki Murakami, Takashi Kaito, Yukihiro Matsuyama, Toshihiko Yamashita, Mamoru Kawakami, Kazuhisa Takahashi, Munehito Yoshida, Seiji Ohtori, Toshihiko Taguchi, Hirotaka Haro, Hiroshi Taneichi, Masashi Yamazaki, Gen Inoue, Kotaro Nishida, Hiroshi Yamada, Daijiro Kabata, Ayumi Shintani, Motoki Iwasaki, Manabu Ito, Naohisa Miyakoshi, Kazuo Yonenobu, Tomoyuki Takura, Joji Mochida
Summary: This study identified significant prognostic factors for outcomes of pharmacological treatment of chronic low back pain, with neuropathic pain component at baseline being a major negative factor. Factors like age, disease duration, history of spinal surgery, and smoking habit had negative effects, while employment status, exercise habit, and depression score had positive effects on outcomes.
JOURNAL OF ORTHOPAEDIC SCIENCE
(2021)
Review
Medicine, General & Internal
Nebojsa Nick Knezevic, Kenneth D. Candido, Johan W. S. Vlaeyen, Jan Van Zundert, Steven P. Cohen
Summary: Low back pain encompasses various types of pain, with diagnostic and therapeutic methods controversial, requiring a comprehensive approach considering biological, psychological, and social factors. Improvement in diagnostic accuracy, treatment algorithms, and multimodal interdisciplinary treatment are essential.
Article
Clinical Neurology
Nadir Tayfun Ozcan, Bilge Basakci Calik, Elif Gur Kabul
Summary: This study aimed to investigate the effects of matrix rhythm therapy (MRT) on pain, disability level, and quality of life in patients with chronic low back pain. The results showed that both the combined physiotherapy program and the additional MRT application had a positive impact on pain, disability level, and quality of life in these patients.
Review
Anesthesiology
Monika Halicka, Rui Duarte, Sharon Catherall, Michelle Maden, Michaela Coetsee, Martin Wilby, Christopher Brown
Summary: Predictors of postoperative pain and disability levels after spinal surgery for chronic back pain vary, with factors such as age, education, and spinal stenosis being associated with pain relief, and factors like preoperative pain, comorbidities, anxiety, and depression being associated with pain relief. Preoperative sensory loss is associated with reduced disability, while factors like job-related resignation and neuroticism are also associated with reduced disability.
CLINICAL JOURNAL OF PAIN
(2022)
Article
Rheumatology
Susan L. Murphy, Anna L. Kratz, Daniel Whibley, Janet L. Poole, Dinesh Khanna
Summary: This study found that fatigue in patients with systemic sclerosis is strongly associated with deficits in social participation, physical function, and quality of life, with fatigue having the greatest impact on social participation.
ARTHRITIS CARE & RESEARCH
(2021)
Article
Rheumatology
Susan L. Murphy, Alain Lescoat, Mary Alore, Michael Hughes, John D. Pauling, Maya Sabbagh, Dinesh Khanna
Summary: There are differences in how people with primary and secondary RP define RP, with primary RP patients more likely to focus on the impact on quality of life and pain, while secondary RP patients tend to emphasize specific body parts and management of attacks. These findings have implications for assessing RP outcomes in different patient populations.
CLINICAL RHEUMATOLOGY
(2021)
Article
Clinical Neurology
Kevin N. Alschuler, Michelle K. Roberts, Tracy E. Herring, Dawn M. Ehde
Summary: This study found that even during COVID-19, psychological distress and risk perception in people with MS are primarily influenced by psychological factors, age, and experiencing symptoms consistent with COVID-19, with minimal contribution from individual differences in health status.
MULTIPLE SCLEROSIS AND RELATED DISORDERS
(2021)
Correction
Rheumatology
Susan L. Murphy, Alain Lescoat, Mary Alore, Michael Hughes, John D. Pauling, Maya Sabbagh, Dinesh Khanna
CLINICAL RHEUMATOLOGY
(2021)
Article
Clinical Neurology
Thomas R. Valentine, Kevin N. Alschuler, Dawn M. Ehde, Anna L. Kratz
Summary: The study found that pain, fatigue, depression, and anxiety are common in patients with multiple sclerosis, often co-occurring. Most patients experienced at least one clinically significant symptom within the year after diagnosis, indicating a significant impact on patients. Symptom severity showed fluctuations at the individual level, highlighting the need for timely screening and treatment.
MULTIPLE SCLEROSIS JOURNAL
(2022)
Review
Rheumatology
Susan L. Murphy, Janet L. Poole, Yen T. Chen, Alain Lescoat, Dinesh Khanna
Summary: This systematic review found that rehabilitation interventions for systemic sclerosis often focus on hand and upper extremity outcomes, and are often multi-component or self-management focused. Despite high study heterogeneity, a significant number of studies showed improvement in intervention groups. Future research could benefit from using common outcome measures and standardizing intervention components.
ARTHRITIS CARE & RESEARCH
(2022)
Article
Clinical Neurology
Kevin N. Alschuler, Daniel Whibley, Anna L. Kratz, Mark P. Jensen, Annette Wundes, Gloria von Geldern, Peiqing Qian, Charles H. Bombardier, Dawn M. Ehde
Summary: The study found that in the first year post-MS/CIS diagnosis, the average QOL was high and stable, with only a few variables predicting baseline QOL and changes over time. This suggests that early assessment of certain factors can help predict current and future QOL outcomes for patients.
JOURNAL OF NEUROLOGY
(2022)
Article
Rheumatology
Susan L. Murphy, Veronica J. Berrocal, Janet L. Poole, Dinesh Khanna
Summary: The study aimed to examine the validity, reliability, and responsiveness to change of the Patient-Reported Outcomes Measurement Information System Self-Efficacy in managing chronic conditions for individuals with systemic sclerosis. Results indicated good internal consistency and significant correlations with depressive symptoms and quality of life measures, showing the measure's ability to differentiate individuals with depressive symptoms and its responsiveness to changes in reported quality of life over a 16-week period.
JOURNAL OF SCLERODERMA AND RELATED DISORDERS
(2022)
Article
Psychology, Clinical
Jamie L. Tingey, Thomas R. Valentine, Anna L. Kratz, Jacob A. Bentley, Dawn M. Ehde, Kevin N. Alschuler
Summary: This study aims to improve our understanding of self-efficacy in individuals newly diagnosed with MS by examining self-efficacy trajectories and identifying patient characteristics associated with trajectories in the first year following diagnosis. The study found that self-efficacy remains relatively stable in the first year following a MS diagnosis, but high symptom severity is associated with decreased self-efficacy at 12-months postdiagnosis. Clinical characteristics, such as MS diagnosis and disability level, also appear to influence the course of self-efficacy in this postdiagnosis year. Timely interventions can enhance self-efficacy and improve specific clinical characteristics, promoting healthy self-management of MS.
REHABILITATION PSYCHOLOGY
(2023)
Article
Clinical Neurology
Kara Link, Lindsey M. Knowles, Kevin N. Alschuler, Dawn M. Ehde
Summary: This study examined the prevalence and characteristics of cannabis use for pain management among adults with multiple sclerosis (MS) and chronic pain. Results showed that 27% of participants used cannabis, with the most common route of administration being oil/tincture. Cannabis users were younger and had higher levels of pain intensity, pain interference, and neuropathic pain.
MULTIPLE SCLEROSIS AND RELATED DISORDERS
(2023)
Article
Psychology, Clinical
Kevin N. Alschuler, Jennifer K. Altman, Dawn M. Ehde
Summary: The study aimed to investigate the feasibility and acceptability of remotely delivered single-session group intervention targeting pain coping in individuals with early MS. Results showed that a majority of participants in the treatment arm were satisfied with the intervention and continued to use the strategies learned; the two groups did not differ significantly on outcomes at any time point, with large standard deviations found on most measures. Further research is needed to understand the immediate effectiveness and long-term impact of the intervention.
REHABILITATION PSYCHOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Susan L. Murphy, Donnamarie Krause, Shawn C. Roll, Girish Gandikota, Mary Barber, Dinesh Khanna
Summary: This study developed an MSUS protocol to evaluate rehabilitation outcomes in systemic sclerosis. The most valid and reliable gray-scale technique was with the transducer in long-axis, floating on gel. Preliminary data indicate that treatment may lead to dermal thinning.
JOURNAL OF DIAGNOSTIC MEDICAL SONOGRAPHY
(2021)
Article
Rheumatology
Susan L. Murphy, Daniel Whibley, Anna L. Kratz, Janet L. Poole, Dinesh Khanna
Summary: Fatigue severity predicted decreased social participation in people with systemic sclerosis, but did not impact physical functioning or quality of life. The level of reported self-efficacy did not moderate the association between fatigue and decline in social participation indicating the need for additional targets in fatigue intervention beyond self-management.
JOURNAL OF SCLERODERMA AND RELATED DISORDERS
(2021)
Review
Rheumatology
Alain Lescoat, Susan L. Murphy, David Roofeh, John D. Pauling, Michael Hughes, Robert Sandler, Francois Zimmermann, Rachel Wessel, Whitney Townsend, Lorinda Chung, Christopher P. Denton, Peter A. Merkel, Virginia Steen, Yannick Allanore, Francesco Del Galdo, Dominique Godard, David Cella, Sue Farrington, Maya H. Buch, Dinesh Khanna
Summary: Systemic sclerosis presents with a diverse range of clinical manifestations and is classified into limited and diffuse cutaneous subgroups. While diffuse cutaneous systemic sclerosis has been the focus of clinical trials, limited cutaneous systemic sclerosis also has significant morbidity and impact on quality of life. The lack of interventional studies for limited cutaneous systemic sclerosis is partly due to a lack of outcome measures, but a proposed composite index specifically for this subgroup could improve clinical trial representation and response to outcomes.
JOURNAL OF SCLERODERMA AND RELATED DISORDERS
(2021)
Article
Psychology, Clinical
Noelle E. Carlozzi, Nicholas R. Boileau, Susan L. Murphy, Tiffany J. Braley, Anna L. Kratz
Summary: The study aimed to validate the Pittsburgh Fatigability Scale in three different groups and found that it exhibited acceptable psychometric properties. However, some measurement estimates did not meet expectations, and item-total correlations for two items were lower than expected.
JOURNAL OF HEALTH PSYCHOLOGY
(2021)