Lrp1/LDL Receptor Play Critical Roles in Mannose 6-Phosphate-Independent Lysosomal Enzyme Targeting

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

ProteomeXchange provides globally coordinated proteomics data submission and dissemination

(2014) Juan A Vizcaíno et al.   NATURE BIOTECHNOLOGY

Decreased bone formation and increased osteoclastogenesis cause bone loss in mucolipidosis II

(2013) Katrin Kollmann et al.   EMBO Molecular Medicine

Assessment and Improvement of Statistical Tools for Comparative Proteomics Analysis of Sparse Data Sets with Few Experimental Replicates

(2013) Veit Schwämmle et al.   JOURNAL OF PROTEOME RESEARCH

Lysosomal dysfunction causes neurodegeneration in mucolipidosis II ‘knock-in’ mice

(2012) K. Kollmann et al.   BRAIN

Mannose 6 Dephosphorylation of Lysosomal Proteins Mediated by Acid Phosphatases Acp2 and Acp5

(2011) G. Makrypidi et al.   MOLECULAR AND CELLULAR BIOLOGY

Cathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis

(2011) D Derocq et al.   ONCOGENE

A Key Enzyme in the Biogenesis of Lysosomes Is a Protease That Regulates Cholesterol Metabolism

(2011) K. Marschner et al.   SCIENCE

A Novel Single-Chain Antibody Fragment for Detection of Mannose 6-Phosphate-Containing Proteins

(2010) Sven Müller-Loennies et al.   AMERICAN JOURNAL OF PATHOLOGY

Golgi-to-phagosome transport of acid sphingomyelinase and prosaposin is mediated by sortilin

(2010) A. Wahe et al.   JOURNAL OF CELL SCIENCE

Loss of N-acetylglucosamine-1-phosphotransferase gamma subunit due to intronic mutation in GNPTG causes mucolipidosis type III gamma: Implications for molecular and cellular diagnostics

(2009) Sandra Pohl et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Delivery of endocytosed membrane proteins to the lysosome

(2009) Paul R. Pryor et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Multiple routes of protein transport from endosomes to the trans Golgi network

(2009) Suzanne R. Pfeffer   FEBS LETTERS

Lentiviral gene ontology (LeGO) vectors equipped with novel drug-selectable fluorescent proteins: new building blocks for cell marking and multi-gene analysis

(2009) K Weber et al.   GENE THERAPY

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

(2009) Guojun Bu   NATURE REVIEWS NEUROSCIENCE

Insulin stimulates hepatic low density lipoprotein receptor-related protein 1 (LRP1) to increase postprandial lipoprotein clearance

(2008) Alexander Laatsch et al.   ATHEROSCLEROSIS

Sortilin mediates the lysosomal targeting of cathepsins D and H

(2008) Maryssa Canuel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sorting of lysosomal proteins

(2008) Thomas Braulke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Multicolor Panel of Novel Lentiviral “Gene Ontology” (LeGO) Vectors for Functional Gene Analysis

(2008) Kristoffer Weber et al.   MOLECULAR THERAPY

Acid phosphatase 5 is responsible for removing the mannose 6-phosphate recognition marker from lysosomal proteins

(2008) P. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA