Article
Geriatrics & Gerontology
Christian Hauck, Andreas Schober, Alexander Schober, Sabine Fredersdorf-Hahn, Ute Hubauer, Andreas Keyser, Lars Maier, Carsten Jungbauer, Ekrem Uecer
Summary: Age is an independent predictor of mortality after ICD implantation for secondary prevention. Mortality rates did not differ significantly between octogenarians and other elderly aged 70-79 years. Appropriate ICD therapy and acute adverse events leading to surgical intervention were not age-related.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2022)
Article
Cardiac & Cardiovascular Systems
Marie Lewenhardt, Fabienne Kreimer, Assem Aweimer, Andreas Pflaumbaum, Andreas Muegge, Michael Gotzmann
Summary: This study analyzed the outcomes of patients of different age groups who received implantable cardioverter-defibrillators (ICD). The results suggest that the indication for primary prophylactic ICD in elderly and very old patients should be critically evaluated. However, age should not be a factor in denying secondary prophylactic ICD implantation.
CLINICAL CARDIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Nso Nso, Mahmoud Nassar, Sofia Lakhdar, Sostanie Enoru, Laura Guzman, Vincent Rizzo, Most S. Munira, Farshid Radparvar, Senthil Thambidorai
Summary: Based on the updated evidence, subcutaneous implantable cardioverter-defibrillator (S-ICD) is safer and more effective than transvenous implantable cardioverter-defibrillator (TV-ICD) as it reduces the incidence of pocket complications, lead displacement or fracture, inappropriate sensing, defibrillation lead failure, pneumothorax/hemothorax, device failure, lead erosion, and all-cause mortality.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Badder Kattih, Felix Operhalski, Felicitas Boeckling, Florian Hecker, Felix Michael, Mate Vamos, Stefan H. Hohnloser, Julia W. Erath
Summary: This study evaluated the clinical outcomes of subcutaneous implantable cardioverter-defibrillator (S-ICD) and single-chamber transvenous (TV-ICD) in an all-comers population and found no significant differences in the composite endpoint, including survival, freedom of hospitalization, and device-associated events, between the two.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Adaya Weissler-Snir, Paul Dorian, Harry Rakowski, Melanie Care, Danna Spears
Summary: The incidence of appropriate ICD therapies in patients with HCM and primary prevention ICDs is lower than previously reported, with a high proportion of patients suffering from ICD-related complications. Traditional risk factors have low predictive utility, while severe late gadolinium enhancement, atrial fibrillation, and young age are important predictors of ventricular tachyarrhythmias in HCM.
Article
Cardiac & Cardiovascular Systems
Arwa Younis, Jeffrey J. Goldberger, Valentina Kutyifa, Wojciech Zareba, Bronislava Polonsky, Helmut Klein, Mehmet K. Aktas, David Huang, James Daubert, Mark Estes, David Cannom, Scott McNitt, Kenneth Stein, Ilan Goldenberg
Summary: A personalized ICD benefit prediction score has been developed to assess the likelihood of prophylactic ICD benefit by integrating the risks of ventricular tachycardia/ventricular fibrillation and non-arrhythmic mortality. Three different benefit groups were identified, based on the predicted risks, providing a reference for decision-making on prophylactic ICD implantation.
EUROPEAN HEART JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Victor Nauffal, Peter Marstrand, Larry Han, Victoria N. Parikh, Adam S. Helms, Jodie Ingles, Daniel Jacoby, Neal K. Lakdawala, Sunil Kapur, Michelle Michels, Anjali T. Owens, Euan A. Ashley, Alexandre C. Pereira, Joseph W. Rossano, Sara Saberi, Christopher Semsarian, James S. Ware, Samuel G. Wittekind, Sharlene Day, Iacopo Olivotto, Carolyn Y. Ho
Summary: Primary prevention ICDs are implanted more frequently in US vs. non-US sites across the spectrum of SCD risk. There was a Lower rate of appropriate ICD therapy in US sites, consistent with a lower-risk population, and no significant difference in SCD in US vs. non-US patients who did not receive an ICD.
EUROPEAN HEART JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Pier D. Lambiase, Dominic A. Theuns, Francis Murgatroyd, Craig Barr, Lars Eckardt, Petr Neuzil, Marcoen Scholten, Margaret Hood, Jurgen Kuschyk, Amy J. Brisben, Nathan Carter, Timothy M. Stivland, Reinoud Knops, Lucas V. A. Boersma
Summary: This study reports the 5-year outcomes of EFFORTLESS registry patients with early generation subcutaneous implantable cardioverter-defibrillator (S-ICD) devices. The study found that the spontaneous shock efficacy remained consistently high over the 5-year period and very few patients required replacement with a transvenous device. Additionally, early arrhythmic episodes did not predict later complications.
EUROPEAN HEART JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Sem Briongos-Figuero, Arcadio Garcia-Alberola, Jeronimo Rubio, Jose Maria Segura, Anibal Rodriguez, Rafael Peinado, Javier Alzueta, Jose B. Martinez-Ferrer, Xavier Vinolas, Joaquin Fernandez de la Concha, Ignasi Anguera, Maria Martin, Laia Cerda, Luisa Perez
Summary: Large-scale studies on modern populations with implantable cardioverter-defibrillators (ICDs) are lacking. The UMBRELLA study analyzed the incidence of arrhythmia, device interventions, and mortality in a diverse group of real-world ICD patients with different heart disorders. Results showed that patients with certain heart conditions had higher risks of appropriate ICD therapies, while patients with other conditions had lower risks. Regardless of the cause, contemporary ICD patients with heart failure-related disorders had a similar risk of ICD life-saving interventions and death.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Aida Ribera, Emmanuel Gimenez, Gerard Oristrell, Dimelza Osorio, Josep Ramon Marsal, Lidia Garcia-Perez, Monica Ballesteros, Eduard Rodenas, Yassin Belahnech, Roxana Escalona, Nuria Rivas, Ivo Roca-Luque, Ignacio Ferreira-Gonzalez, Mireia Espallargues
Summary: This study evaluated the cost-effectiveness of implantable cardioverter-defibrillators (ICD) for the primary prevention of cardiac arrhythmias. The results showed that ICD systems are cost-effective for patients with ischemic and nonischemic heart disease younger than 68 years old. However, for older nonischemic patients, the cost-effectiveness ratio is higher.
REVISTA ESPANOLA DE CARDIOLOGIA
(2022)
Review
Medicine, General & Internal
Wen Zhuo, Hualong Liu, Linghua Fu, Weiguo Fan, Kui Hong
Summary: A meta-analysis was conducted to assess the effect of digitalis on recipients of implantable cardioverter defibrillators (ICD) or cardiac resynchronization therapy defibrillators (CRT-D). The results showed that digitalis was associated with an increased rate of appropriate shocks and a shortened time to first appropriate shock in ICD or CRT-D recipients. Furthermore, digitalis therapy was found to increase all-cause mortality in ICD recipients, but had no effect on the mortality rate of CRT-D recipients or patients who received ICD or CRT-D therapy.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Marit van Barreveld, Tom E. Verstraelen, Pascal F. H. M. van Dessel, Lucas V. A. Boersma, Peter Paul H. M. Delnoy, Anton E. Tuinenburg, Dominic A. M. J. Theuns, Pepijn H. van der Voort, Geert-Jan Kimman, Erik Buskens, Aeilko H. Zwinderman, Arthur A. M. Wilde, Marcel G. W. Dijkgraaf
Summary: This study in a Dutch cohort of implantable cardioverter-defibrillator patients found that 13.6% experienced complications, with 7.8% being major complications. Lead-related issues and infections were the most common. Stricter implant indication criteria could potentially reduce complications.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Jeroen Dauw, Pieter Martens, Petra Nijst, Evelyne Meekers, Sebastien Deferm, Henri Gruwez, Maximo Rivero-Ayerza, Hugo Van Herendael, Laurent Pison, Dieter Nuyens, Matthias Dupont, Wilfried Mullens
Summary: The aim of this study was to evaluate the predictive ability of the MADIT-ICD benefit score in identifying heart failure patients who would benefit most from CRT-D and compare it with a multidisciplinary expert centre approach. The results showed that the MADIT-ICD benefit score can identify patients who would benefit most from CRT-D and its predictive power is comparable to multidisciplinary judgement.
Article
Cardiac & Cardiovascular Systems
Ari Pelli, M. Juhani Junttila, Tuomas Kentta, Simon Schlogl, Markus Zabel, Marek Malik, Tobias Reichlin, Rik Willems, Marc A. Vos, Markus Harden, Tim Friede, Christian Sticherling, Heikki Huikuri
Summary: This study analyzed a large cohort of ICD patients and control patients to determine the predictive value of ECG markers, with pathological Q waves identified as a strong predictor of ICD benefit in primary prophylactic ICD patients. Excess mortality among patients with Q waves seems to be due to arrhythmic death, which can be prevented by ICD.
Article
Cardiac & Cardiovascular Systems
Lorne J. Gula, Asher Frydman, Habib R. Khan, George J. Klein, Peter Leong-Sit, Jaimie Manlucu, Jason D. Roberts, Anthony S. L. Tang, Raymond Yee, Allan C. Skanes
Summary: Patients with mildly impaired LV function and hemodynamically tolerated VT receive appropriate ICD therapies over the 3 years following implant. Recurrent VT/VF rates can be much more rapid after ICD placement, with 23% of patients going on to receive appropriate ICD shocks.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)