Autophagy Is Indispensable for the Self-Renewal and Quiescence of Ovarian Cancer Spheroid Cells with Stem Cell-Like Properties

Autophagy maintains the stemness of ovarian cancer stem cells by FOXA2.

(2017) Qiaohua Peng et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Autophagy inhibition reduces chemoresistance and tumorigenic potential of human ovarian cancer stem cells

(2017) Anna Pagotto et al.   Cell Death & Disease

Inhibition of autophagy with bafilomycin and chloroquine decreases mitochondrial quality and bioenergetic function in primary neurons

(2017) Matthew Redmann et al.   Redox Biology

Identification of novel targets of diabetic nephropathy and PEDF peptide treatment using RNA-seq

(2016) Ana Rubin et al.   BMC GENOMICS

p62 in Cancer: Signaling Adaptor Beyond Autophagy

(2016) Jorge Moscat et al.   CELL

Autophagy protects ovarian cancer-associated fibroblasts against oxidative stress

(2016) Qian Wang et al.   CELL CYCLE

Metabolic risk factors and mechanisms of disease in epithelial ovarian cancer: A review

(2016) Eric R. Craig et al.   GYNECOLOGIC ONCOLOGY

Autophagy maintains stemness by preventing senescence

(2016) Laura García-Prat et al.   NATURE

Redox Modulating NRF2: A Potential Mediator of Cancer Stem Cell Resistance

(2016) In-geun Ryoo et al.   Oxidative Medicine and Cellular Longevity

Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells

(2015) Xuejiao Zhao et al.   Autophagy

Autophagy in malignant transformation and cancer progression

(2015) L. Galluzzi et al.   EMBO JOURNAL

Oxidative stress and autophagy: the clash between damage and metabolic needs

(2014) G Filomeni et al.   CELL DEATH AND DIFFERENTIATION

Dynamic Changes in Intracellular ROS Levels Regulate Airway Basal Stem Cell Homeostasis through Nrf2-Dependent Notch Signaling

(2014) Manash K. Paul et al.   Cell Stem Cell

Role of Autophagy in Cisplatin Resistance in Ovarian Cancer Cells

(2014) Juan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Developing ovarian cancer stem cell models: laying the pipeline from discovery to clinical intervention

(2014) Brendan Ffrench et al.   Molecular Cancer

Metabolic requirements for the maintenance of self-renewing stem cells

(2014) Keisuke Ito et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The NRF2-KEAP1 Pathway Is an Early Responsive Gene Network in Arsenic Exposed Lymphoblastoid Cells

(2014) Emilio J. Córdova et al.   PLoS One

Ovarian Cancer Spheroid Cells with Stem Cell-Like Properties Contribute to Tumor Generation, Metastasis and Chemotherapy Resistance through Hypoxia-Resistant Metabolism

(2014) Jianqun Liao et al.   PLoS One

An Overview of Autophagy: Morphology, Mechanism, and Regulation

(2013) Katherine R. Parzych et al.   ANTIOXIDANTS & REDOX SIGNALING

Salinomycin induces cell death with autophagy through activation of endoplasmic reticulum stress in human cancer cells

(2013) Tianliang Li et al.   Autophagy

Cancer stem cells, a fuzzy evolving concept: A cell population or a cell property?

(2013) Aline Antoniou et al.   CELL CYCLE

Oncogenic functions of the transcription factor Nrf2

(2013) Irene Gañán-Gómez et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2 regulates haematopoietic stem cell function

(2013) Jennifer J. Tsai et al.   NATURE CELL BIOLOGY

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Molecular regulation of stem cell quiescence

(2013) Tom H. Cheung et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Glutathione participates in the modulation of starvation-induced autophagy in carcinoma cells

(2012) Enrico Desideri et al.   Autophagy

Propofol induces proliferation and invasion of gallbladder cancer cells through activation of Nrf2

(2012) Lingmin Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

A family business: stem cell progeny join the niche to regulate homeostasis

(2012) Ya-Chieh Hsu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nrf2–MafG heterodimers contribute globally to antioxidant and metabolic networks

(2012) Yosuke Hirotsu et al.   NUCLEIC ACIDS RESEARCH

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

(2011) Monika Mortensen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PERK Integrates Autophagy and Oxidative Stress Responses To Promote Survival during Extracellular Matrix Detachment

(2011) A. Avivar-Valderas et al.   MOLECULAR AND CELLULAR BIOLOGY

Reactive Oxygen Species Mediate Oxidized Low-Density Lipoprotein-Induced Inhibition of Oct-4 Expression and Endothelial Differentiation of Bone Marrow Stem Cells

(2010) Tiewei Lu et al.   ANTIOXIDANTS & REDOX SIGNALING

Current and emerging biomarkers in breast cancer: prognosis and prediction

(2010) Marion T Weigel et al.   ENDOCRINE-RELATED CANCER

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Human Aldehyde Dehydrogenase in Normal and Cancer Stem Cells

(2010) Irene Ma et al.   Stem Cell Reviews and Reports

Mechanisms of Stem Cell Self-Renewal

(2009) He Shenghui et al.   Annual Review of Cell and Developmental Biology

Association of reactive oxygen species levels and radioresistance in cancer stem cells

(2009) Maximilian Diehn et al.   NATURE

Identification and Characterization of Ovarian Cancer-Initiating Cells from Primary Human Tumors

(2008) S. Zhang et al.   CANCER RESEARCH

The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells

(2008) Zhen Lu et al.   JOURNAL OF CLINICAL INVESTIGATION

Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival

(2007) Christopher Fung et al.   MOLECULAR BIOLOGY OF THE CELL