Review
Medicine, General & Internal
Vini Mehta, Gargi S. Sarode, Vishnu Teja Obulareddy, Tanvi Sharma, Shruti Kokane, Marco Cicciu, Giuseppe Minervini
Summary: This review aims to investigate the complications, survival, recurrence rate, and outcomes of sinonasal ameloblastoma (SNA). The study found that SNA has similar histological features to gnathic ameloblastoma but presents different clinical characteristics. It may cause nasal cavity and sinus obstruction and primarily affects older patients. Treatment may involve excising a significant portion of the maxilla, requiring maxillofacial prosthetic rehabilitation.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Pathology
Malgorzata Chlopek, Jerzy Lasota, Lester D. R. Thompson, Magdalena Szczepaniak, Alina Kuzniacka, Kinga Hincza, Kamila Kubicka, Maciej Kaczorowski, Michael Newford, Yalan Liu, Abbas Agaimy, Wojciech Biernat, Monika Durzynska, Ireneusz Dziuba, Arndt Hartmann, Shingo Inaguma, Ewa Izycka-Swieszewska, Hiroyuki Kato, Janusz Kopczynski, Michal Michal, Michael Michal, Rafal Peksa, Monika Prochorec-Sobieszek, Anna Starzynska, Satoru Takahashi, Bartosz Wasag, Artur Kowalik, Markku Miettinen
Summary: This study examined the mutational profile of sinonasal mucosal melanoma, revealing the presence of NRAS and other key components and regulators of the Ras-MAPK signaling pathway in the majority of cases.
Article
Dermatology
Zhen Guo, Qiongyang Liu, Shijie Lan, Ningning Niu, Jianping Gui, Yiqun Zhang, Di Wu
Summary: This study analyzed the epidemiology and clinicopathologic characteristics of melanoma patients in Northeast China. The study found that vascular invasion may be a prognostic factor in melanoma patients. Furthermore, there were significant differences in disease location, pathologic subtype, gene status, and survival prognosis between the population of Northeast China and Caucasian population.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
(2023)
Review
Dermatology
C. C. Darmawan, J. Ohn, J. -H. Mun, S. Kim, Y. Lim, S. J. Jo, Y. -G. Kim, B. Kim, M. -W. Seong, B. J. Kim, C. Lee, Y. Kwak, H. J. Chung, A. Viros, D. Y. Lee
Summary: Nail melanoma (NM) is a challenging differential diagnosis for patients with longitudinal melanonychia. Clinical and histopathological analyses are essential for accurate diagnosis, and surgery is the primary treatment. Targeted therapy and immunotherapy may be considered for advanced stages of NM.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2022)
Review
Otorhinolaryngology
Armando De Virgilio, Andrea Costantino, Federica Canzano, Remo Accorona, Giuseppe Mercante, Fabio Ferreli, Luca Malvezzi, Giovanni Colombo, Raul Pellini, Giuseppe Spriano
Summary: The regional recurrence rate of sinonasal mucosal melanoma (SNMM) after primary treatment is considerable, warranting further prospective studies to determine the potential for recommending elective neck treatment in certain patient subgroups.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2021)
Review
Pathology
Josephine K. Dermawan, Rumeal D. Whaley, Sandra Gjorgova Gjeorgjievski, Omar Habeeb, Steven D. Billings
Summary: Myxofibrosarcoma is a rare malignant tumor that usually occurs in the limbs. This case series reports the first cases of myxofibrosarcoma in the sinonasal region, with distinctive vascular pattern and myxoid stroma. Surgical resection and radiotherapy were effective treatments in these cases, with low recurrence and metastasis rates.
Article
Pathology
Ying-Ju Kuo, James S. Lewis, Changwen Zhai, Yun-An Chen, Rebecca D. Chernock, Min-Shu Hsieh, Ming-Ying Lan, Chien-Kuan Lee, Ilan Weinreb, Jen-Fan Hang
Summary: A novel DEK-AFF2 fusion has been identified in sinonasal SCC with deceptively bland morphology. These tumors tend to progress locoregionally and occasionally develop metastases, high-grade transformation, or extensive local destruction eventually leading to death, justifying more aggressive clinical management. The proposed new terminology of DEK-AFF2 fusion-associated papillary SCC of the sinonasal tract better describes this distinct entity.
Review
Medicine, General & Internal
Giorgio Sileo, Marco Valentini, Giacomo Gravante, Giulia Monti, Alberto D. Arosio, Maurizio Bignami, Paolo Battaglia, Paolo Castelnuovo, Mario Turri-Zanoni
Summary: Frontal sinus involvement by malignant tumors is rare and requires further investigation to better understand its epidemiology, treatment options, and outcomes. This retrospective study and systematic literature review provide valuable insights into the subject. The study found that frontal sinus malignancies have a poor prognosis, and multidisciplinary management with histology-driven treatments is essential for improving outcomes and reducing morbidity.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Oncology
Shiran Sun, Ye Zhang, Xiaodong Huang, Kai Wang, Yuan Qu, Runye Wu, Xuesong Chen, Jingbo Wang, Jianghu Zhang, Jingwei Luo, Guozhen Xu, Ye-Xiong Li, Junlin Yi
Summary: This study retrospectively analyzed the treatment outcomes of 107 SNMM patients and found a significant reduction in regional relapse rate with ENI, especially in relapses occurring in levels Ib and II. Further research is needed to confirm these findings.
RADIOTHERAPY AND ONCOLOGY
(2023)
Review
Ophthalmology
Lisa Y. Lin, John H. Stone, Victor D. Liou, Anna M. Stagner, N. Grace Lee
Summary: This article retrospectively collects and describes 6 cases of eosinophilic angiocentric fibrosis (EAF) involving the orbit, and reviews a total of 31 cases. The study finds that EAF involving the orbit is relatively rare and usually results from extension from adjacent sinuses. Clinical symptoms commonly include nasal symptoms, proptosis, periorbital swelling, and pain. Surgical debulking and immunosuppressive agents such as rituximab have been shown to stabilize the disease.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2023)
Review
Oncology
Florian Chatelet, Francois Simon, Vincent Bedarida, Nicolas Le Clerc, Homa Adle-Biassette, Philippe Manivet, Philippe Herman, Benjamin Verillaud
Summary: Sinonasal cancers are rare and require surgery as the first step of the therapeutic strategy, possibly accompanied by adjuvant therapies. Surgical excision can be performed through open, endoscopic, or combined approaches, with the choice based on general and specific criteria related to tumor characteristics, patient status, and surgeon preference. This review provides an overview of surgical techniques for sinonasal malignant tumors, with a focus on recent advancements in transnasal endoscopic surgery, and discusses criteria for selecting appropriate techniques based on oncological outcomes, morbidity, and histologic subtypes.
Article
Orthopedics
Lei Cao, Yuan Wu, Shu-Man Han, Tao Sun, Bao-Hai Yu, Feng Gao, Wen-Juan Wu, Bu-Lang Gao
Summary: Dedifferentiated chondrosarcoma is a deadly disease with dual components of chondrosarcoma and non-chondrosarcoma, showing common features of central chondrosarcoma with cortical destruction, soft tissue mass, and pathological fractures on imaging.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Review
Oncology
Yingying Han, Qingjiao Li, Dan Wang, Lushan Peng, Tao Huang, Chunlin Ou, Keda Yang, Junpu Wang
Summary: Intravascular large B-cell lymphoma (IVLBCL) is a rare and highly malignant non-Hodgkin B-cell lymphoma. This study aims to explore the clinicopathologic features of IVLBCL and improve its diagnosis. Through the retrospective analysis of four new cases and literature cases, the study found that IVLBCL has variable clinical presentations, distinct histopathological characteristics, and specific immunophenotypes.
FRONTIERS IN ONCOLOGY
(2022)
Article
Pathology
Huan Wang, Changwen Zhai, Chen Zhang, Quan Liu, Huankang Zhang, Xicai Sun, Lan Lin, Hongmeng Yu, Dehui Wang
Summary: Acinic cell carcinoma (AiCC) in the nasal cavity and paranasal sinuses is rare, with similar clinical and histopathological characteristics to salivary gland AiCC. NR4A3 is a reliable biomarker for distinguishing sinonasal AiCC from other sinonasal carcinomas.
Article
Medicine, General & Internal
Munechika Tsumura, Seiichiro Makihara, Asami Nishikori, Yuka Gion, Toshiaki Morito, Shotaro Miyamoto, Tomoyuki Naito, Kensuke Uraguchi, Aiko Oka, Tomoyasu Tachibana, Yorihisa Orita, Shin Kariya, Mitsuhiro Okano, Mizuo Ando, Yasuharu Sato
Summary: This study found that HPV infection, young adulthood, diabetes mellitus, and advanced tumor stage may be associated with the recurrence of sinonasal inverted papilloma.
