Article
Rheumatology
Hiral Master, Tuhina Neogi, Michael LaValley, Louise M. Thoma, Yuqing Zhang, Dana Voinier, Meredith B. Christiansen, Daniel K. White
Summary: This study found that in adults, walking slower than 1.22 m/s is associated with increased mortality risk, regardless of decline over the previous year.
JOURNAL OF RHEUMATOLOGY
(2021)
Article
Neurosciences
Annika Toots, Magdalena Eriksson Domellof, Lillemor Lundin-Olsson, Yngve Gustafson, Erik Rosendahl
Summary: This study found that slower backward walking speed is not associated with increased risk of falls in older adults with dementia. However, slower backward walking speed relative to forward walking speed (greater directional difference) is associated with fewer falls, possibly indicating a protective response. This novel research suggests that assessing walking speed in multiple directions may inform fall risk in adults with dementia.
Article
Biochemistry & Molecular Biology
Luz Herrero-Manley, Ana Alabajos-Cea, Luis Suso-Marti, Enrique Viosca-Herrero, Isabel Vazquez-Arce
Summary: The study aimed to test the practicality of the existing diagnostic criteria for early knee osteoarthritis (EKOA) and evaluate the clinical progression of both healthy subjects at risk and patients diagnosed with EKOA. The participants were classified into EKOA and healthy subjects based on disability, pain, and self-reported variables. Most participants remained in their original classification, although some were reclassified during the follow-ups. The current diagnostic criteria could lead to misdiagnosis due to fluctuations in patients' conditions.
Article
Geriatrics & Gerontology
Rumei Yang, Yin Liu, Yun Jiang, Daniel J. M. Fleming, Elizabeth B. Fauth
Summary: This study aimed to examine the impact of cancer on functional limitation trajectories and explore contributing factors. Results showed that there was a general trend of functional decline among Chinese middle-aged and older adults, with cancer diagnosis potentially influencing the rate of decline. Pain among cancer survivors was found to be associated with higher levels of functional limitations.
Article
Health Care Sciences & Services
Brianna I. I. Flynn, Emily M. M. Javan, Eugenia Lin, Zoe Trutner, Karl Koenig, Kenoma O. O. Anighoro, Eucharist Kun, Alaukik Gupta, Tarjinder Singh, Prakash Jayakumar, Vagheesh M. Narasimhan
Summary: Electronic health records are often incomplete, leading to reduced power in genetic association studies. However, image-based phenotyping, such as using knee DXA scans for knee osteoarthritis diagnosis, provides an unbiased way to identify disease cases. Deep-learning models trained on knee DXA scans can effectively diagnose knee osteoarthritis cases and improve the discovery of genome-wide significant loci. Additionally, image-based phenotyping can reveal epidemiological associations not captured in electronic health records, such as the link between knee osteoarthritis and increased risk of adult fractures.
NPJ DIGITAL MEDICINE
(2023)
Article
Geriatrics & Gerontology
Momoko Yamagata, Hiroshige Tateuchi, Itsuroh Shimizu, Junya Saeki, Noriaki Ichihashi
Summary: This study found that a high variance in segmental configurations destabilizing the CoM in the vertical direction was related to future falls, suggesting that UCM analysis variables can be useful for evaluating fall risk.
Article
Rehabilitation
Sean D. Rundell, Amol Karmarkar, Michael Nash, Kushang V. Patel
Summary: The study found that older adults with back pain who have multiple chronic conditions, especially arthritis, depression, and anxiety, are associated with poor physical functioning and an increased risk of falls over time.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Orthopedics
Munira M. Al Mahrouqi, Bill Vicenzino, David A. MacDonald, Michelle D. Smith
Summary: This study investigated the falls history in individuals with chronic ankle symptoms and compared it to those without the symptoms. The results showed that individuals with chronic ankle symptoms had a higher occurrence of falls and more severe injuries compared to the controls. They also had higher concern about falling and lower balance confidence. These findings highlight the importance of assessing falls and concerns about falling in individuals with chronic ankle symptoms.
JOURNAL OF FOOT AND ANKLE RESEARCH
(2023)
Article
Geriatrics & Gerontology
Hirotaka Iijima, Tomoki Aoyama
Summary: The coexistence of sarcopenia and knee OA in older adults increases the risk of falls, with individuals in the sarcopenia + knee OA group having higher odds of recurrent falls compared to controls. This study introduces the concept of sarcopenic knee OA as a subgroup associated with a higher risk of falls, which should be further validated in future large cohort studies.
Article
Orthopedics
W. Wu, A. L. Bryant, R. S. Hinman, K. L. Bennell, B. R. Metcalf, M. Hall, P. K. Campbell, K. L. Paterson
Summary: Medial and lateral knee contact forces (KCFs) differ across grades of radiographic knee osteoarthritis (OA) severity, but are not associated with knee pain severity. Medial KCFs during early and middle stance are higher in participants with moderate and severe OA compared to mild OA. In contrast, lateral KCFs are higher in mild OA during middle to late stance. The external loading component (KAM) of medial KCF during middle to late stance is greater in participants with moderate and severe OA, while the internal (muscle) component is greater in participants with moderate and severe OA during early stance. There are no associations between medial KCF and knee pain in any radiographic OA grade.
OSTEOARTHRITIS AND CARTILAGE
(2022)
Article
Orthopedics
Qiang Liu, Zhikun Li, Manuela Ferreira, Barton Wise, David J. Hunter, Ke Tao, Jianhao Lin, Yuqing Zhang
Summary: Recent knee injury, more severe radiographic osteoarthritis, and lower quadriceps strength were associated with an increased risk of knee pain exacerbation during walking.
JOURNAL OF ORTHOPAEDIC & SPORTS PHYSICAL THERAPY
(2021)
Article
Geriatrics & Gerontology
Tamer Ahmed, Carmen-Lucia Curcio, Mohammad Auais, Afshin Vafaei, Catherine M. Pirkle, Ricardo Oliveira Guerra, Fernando Gomez
Summary: This study investigated the longitudinal relationship between falls and life-space mobility in older adults. It found that individuals with lower life-space mobility were more likely to experience recurrent falls or injurious falls, especially among women, those with insufficient income, and comorbidities. However, improvements in life-space mobility were observed over time for some individuals with recurrent or injurious falls.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2021)
Article
Medicine, General & Internal
Nico Magni, Jill Collier, Peter McNair, David A. Rice
Summary: The study found that 42% of patients with symptomatic hand OA experienced neuropathic pain, which was associated with higher pain intensity. Pain intensity was correlated with the number of pain medications and body schema alterations, but not with psychological factors, hand function, and sleep.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Orthopedics
Susan Mayes, Peter Smith, Debbie Stuart, Adam Semciw, Jill Cook
Summary: The research found that elite ballet dancers did not negatively affect cartilage health over 5 years, with most cartilage defects not progressing. Cartilage defects were related to low femoral neck-shaft angles, and the impact of cartilage defects on dance participation and pain levels was minimal.
CLINICAL JOURNAL OF SPORT MEDICINE
(2021)
Article
Clinical Neurology
Beata Lindholm, Christina Brogardh, Per Odin, Peter Hagell
Summary: The study identified predictors for falls/near falls in Parkinson’s disease, including history of falls, abnormal tandem gait, and lower MMSE scores. These factors not only affect the fall risk in the short term but also in the long term among patients with PD.
JOURNAL OF NEUROLOGY
(2021)
Article
Orthopedics
Hiroshi Yamada, Hiroyuki Oka, Hiroshi Iwasaki, Toru Endo, Masahiko Kioka, Yuyu Ishimoto, Keiji Nagata, Noboru Takiguchi, Hiroshi Hashizume, Akihito Minamide, Yukihiro Nakagawa, Masaki Kawai, Shunji Tsutsui, Munehito Yoshida
JOURNAL OF ORTHOPAEDIC SCIENCE
(2015)
Article
Clinical Neurology
Masatoshi Teraguchi, Noriko Yoshimura, Hiroshi Hashizume, Shigeyuki Muraki, Hiroshi Yamada, Hiroyuki Oka, Akihito Minamide, Hiroyuki Nakagawa, Yuyu Ishimoto, Keiji Nagata, Ryohei Kagotani, Sakae Tanaka, Hiroshi Kawaguchi, Kozo Nakamura, Toru Akune, Munehito Yoshida
Article
Clinical Neurology
Keiji Nagata, Hiroshi Hashizume, Hiroshi Yamada, Munehito Yoshida
EUROPEAN SPINE JOURNAL
(2017)
Article
Multidisciplinary Sciences
Hiroki Iwahashi, Noriko Yoshimura, Hiroshi Hashizume, Hiroshi Yamada, Hiroyuki Oka, Ko Matsudaira, Kazunori Shinto, Yuyu Ishimoto, Keiji Nagata, Masatoshi Teraguchi, Ryohei Kagotani, Shigeyuki Muraki, Toru Akune, Sakae Tanaka, Hiroshi Kawaguchi, Kozo Nakamura, Akihito Minamide, Yukihiro Nakagawa, Munehito Yoshida
Article
Multidisciplinary Sciences
Masatoshi Teraguchi, Noriko Yoshimura, Hiroshi Hashizume, Shigeyuki Muraki, Hiroshi Yamada, Hiroyuki Oka, Akihito Minamide, Yuyu Ishimoto, Keiji Nagata, Ryohei Kagotani, Sakae Tanaka, Hiroshi Kawaguchi, Kozo Nakamura, Toru Akune, Munehito Yoshida
Article
Clinical Neurology
Keiji Nagata, Noriko Yoshimura, Hiroshi Hashizume, Yuyu Ishimoto, Shigeyuki Muraki, Hiroshi Yamada, Hiroyuki Oka, Hiroshi Kawaguchi, Toru Akune, Sakae Tanaka, Kozo Nakamura, Munehito Yoshida
EUROPEAN SPINE JOURNAL
(2017)
Article
Orthopedics
M. Teraguchi, N. Yoshimura, H. Hashizume, H. Yamada, H. Oka, A. Minamide, K. Nagata, Y. Ishimoto, R. Kagotani, H. Kawaguchi, S. Tanaka, T. Akune, K. Nakamura, S. Muraki, M. Yoshida
OSTEOARTHRITIS AND CARTILAGE
(2017)
Article
Clinical Neurology
Yuyu Ishimoto, Noriko Yoshimura, Shigeyuki Muraki, Hiroshi Yamada, Keiji Nagata, Hiroshi Hashizume, Noboru Takiguchi, Akihito Minamide, Hiroyuki Oka, Sakae Tanaka, Hiroshi Kawaguchi, Kozo Nakamura, Toru Akune, Munehito Yoshida
Article
Rheumatology
Shigeyuki Muraki, Toru Akune, Keiji Nagata, Yuyu Ishimoto, Munehito Yoshida, Fumiaki Tokimura, Sakae Tanaka, Hiroshi Kawaguchi, Kozo Nakamura, Hiroyuki Oka, Noriko Yoshimura
CLINICAL RHEUMATOLOGY
(2015)
Article
Endocrinology & Metabolism
Keiji Nagata, Munehito Yoshida, Yuyu Ishimoto, Hiroshi Hashizume, Hiroshi Yamada, Noriko Yoshimura
JOURNAL OF BONE AND MINERAL METABOLISM
(2014)
Article
Endocrinology & Metabolism
Ryohei Kagotani, Munehito Yoshida, Shigeyuki Muraki, Hiroyuki Oka, Hiroshi Hashizume, Hiroshi Yamada, Yoshio Enyo, Keiji Nagata, Yuyu Ishimoto, Masatoshi Teraguchi, Sakae Tanaka, Kozo Nakamura, Hiroshi Kawaguchi, Toru Akune, Noriko Yoshimura
JOURNAL OF BONE AND MINERAL METABOLISM
(2015)
Article
Rheumatology
Hiroshi Hashizume, Noriko Yoshimura, Keiji Nagata, Nobuyuki Miyazaki, Yuyu Ishimoto, Ryoko Nishiyama, Hiroyuki Oka, Hiroshi Yamada, Munehito Yoshida
MODERN RHEUMATOLOGY
(2014)
Article
Rheumatology
Shigeyuki Muraki, Toru Akune, Keiji Nagata, Yuyu Ishimoto, Munehito Yoshida, Fumiaki Tokimura, Sakae Tanaka, Hiroyuki Oka, Hiroshi Kawaguchi, Kozo Nakamura, Noriko Yoshimura
MODERN RHEUMATOLOGY
(2014)
Article
Orthopedics
M. Teraguchi, N. Yoshimura, H. Hashizume, S. Muraki, H. Yamada, A. Minamide, H. Oka, Y. Ishimoto, K. Nagata, R. Kagotani, N. Takiguchi, T. Akune, H. Kawaguchi, K. Nakamura, M. Yoshida
OSTEOARTHRITIS AND CARTILAGE
(2014)
Article
Endocrinology & Metabolism
N. Yoshimura, K. Nagata, S. Muraki, H. Oka, M. Yoshida, Y. Enyo, R. Kagotani, H. Hashizume, H. Yamada, Y. Ishimoto, M. Teraguchi, S. Tanaka, H. Kawaguchi, Y. Toyama, K. Nakamura, T. Akune
OSTEOPOROSIS INTERNATIONAL
(2014)