Review
Hospitality, Leisure, Sport & Tourism
Jakub Mesinovic, Paul Jansons, Ayse Zengin, Barbora de Courten, Alexander J. Rodriguez, Robin M. Daly, Peter R. Ebeling, David Scott
Summary: The study compared the effects of diet-induced weight loss alone and in combination with exercise on bone mineral density in adults with overweight and obesity. The findings showed that diet-induced weight loss led to greater bone loss at the femoral neck, and exercise did not mitigate bone loss at the total hip and lumbar spine.
JOURNAL OF SPORT AND HEALTH SCIENCE
(2021)
Article
Nutrition & Dietetics
Monica C. Serra, Alice S. Ryan
Summary: The study compared changes in bone mineral density (BMD) during weight loss and regain periods in overweight postmenopausal women who underwent a 6-month aerobic exercise intervention. Results indicated that less loss of appendicular lean mass and greater increases in VO(2)max during the weight loss phase were associated with attenuated BMD loss during weight regain.
Article
Nutrition & Dietetics
Seth A. Creasy, Liza Wayland, Shelby L. Panter, Sarah A. Purcell, Rebecca Rosenberg, Erik A. Willis, Bethelhem Shiferaw, Laura Grau, Matthew J. Breit, Daniel H. Bessesen, Edward L. Melanson, Victoria A. Catenacci
Summary: The purpose of this study was to evaluate the feasibility and acceptability of randomizing adults with overweight and obesity to morning or evening aerobic exercise. The study found that both morning and evening exercise sessions were well-received and had high levels of adherence. Additionally, both groups experienced increases in total daily energy expenditure, with the morning group having an increase in energy intake and the evening group having a decrease in energy intake. Further research is needed to understand how exercise timing affects energy balance and weight regulation.
Article
Endocrinology & Metabolism
Simona Panunzi, Sabina Maltese, Andrea De Gaetano, Esmeralda Capristo, Stefan R. Bornstein, Geltrude Mingrone
Summary: Effective weight loss interventions for individuals with obesity include bariatric surgery, low-calorie diet and exercise, and intensive weight loss and exercise. Every 1% weight loss contributes to reducing knee osteoarthritis pain and improving physical function.
Article
Nursing
Natalie Pavlovic, Justine Naylor, Robert Boland, Ian A. Harris, Victoria M. Flood, Furkan Genel, Manxin Gao, Danella Hackett, Carol Vleeskens, Bernadette Brady
Summary: This study aimed to explore the barriers and enablers to weight management among obese individuals waiting for total knee or hip arthroplasty. Through individual interviews with patients with end-stage osteoarthritis, four themes were identified as underlying successful weight management: beliefs, adaptability, navigating healthcare, and sociocultural context.
JOURNAL OF CLINICAL NURSING
(2023)
Article
Oncology
Justin C. Brown, David B. Sarwer, Andrea B. Troxel, Kathleen Sturgeon, Angela M. DeMichele, Crystal S. Denlinger, Kathryn H. Schmitz
Summary: In survivors of breast cancer with overweight or obesity, exercise plus diet improved select health-related quality of life end points at week 52.
Article
Nutrition & Dietetics
Dan Lin, Kathleen M. M. Sturgeon, Brett R. R. Gordon, Justin C. C. Brown, Dorothy D. D. Sears, David B. B. Sarwer, Kathryn H. H. Schmitz
Summary: Adipocyte dysregulation is a mechanism connecting overweight and breast cancer recurrence. Exercise and weight loss can lower the risk of breast cancer recurrence in survivors with overweight or obesity, which may be due to changes in leptin levels and the adiponectin to leptin ratio. The WISER Survivor trial studied the effects of exercise, weight loss, and the combination of exercise and weight loss on adipokine levels in overweight or obese breast cancer survivors. It was found that weight loss alone or in combination with exercise significantly reduced leptin levels and increased the adiponectin to leptin ratio. However, exercise alone did not have an impact on these adipokine levels. Overall, weight loss, especially a reduction of ≥5%, was associated with decreased leptin levels and improved adipokine secretion profile.
Review
Nutrition & Dietetics
Sarah J. Wherry, Ryan M. Miller, Sarah H. Jeong, Kristen M. Beavers
Summary: Caloric restriction-induced weight loss can lead to bone density loss in older adults, and while exercise has positive effects on maintaining bone density, its effectiveness in mitigating CR-induced bone loss remains uncertain.
Article
Geriatrics & Gerontology
Andrea M. Brennan, Robert A. Standley, Steven J. Anthony, Kory E. Grench, Nicole L. Helbling, James P. DeLany, Heather H. Cornnell, Fanchao Yi, Maja Stefanovic-Racic, Frederico G. S. Toledo, Paul M. Coen, Elvis A. Carnero, Bret H. Goodpaster
Summary: Exercise with weight loss improves insulin sensitivity, aerobic capacity, and body composition in older obese adults. It also reduces ectopic fat and preserves lean mass and strength. However, weight loss alone may lead to decreased lean mass and strength. Therefore, regular exercise is important for older adults aiming to lose weight in order to achieve cardiometabolic and functional benefits that may not occur with calorie restriction-induced weight loss alone.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2022)
Article
Medicine, General & Internal
Deborah B. Horn, Christopher Damsgaard, Kathi Earles, Sheba Mathew, Amanda E. Nelson
Summary: Patients with osteoarthritis (OA) and obesity often self-manage their condition for an average of five years before seeking medical care, discussing treatment options and weight management upon diagnosis, with few patients discussing anti-obesity medication with their primary care physicians despite interest. Physicians have mixed perceptions of patient motivation for weight loss, indicating a barrier in obesity management for patients with OA.
POSTGRADUATE MEDICINE
(2021)
Article
Endocrinology & Metabolism
Florencio Diniz-Sousa, Lucas Veras, Giorjines Boppre, Vitor Devezas, Hugo Santos-Sousa, John Preto, Leandro Machado, Joao Paulo Vilas-Boas, Jose Oliveira, Helder Fonseca
Summary: Our study found that gravitational loading only decreased during the first month after surgery and remained stable thereafter, and these changes do not seem to explain BS-induced bone loss. The association between weight and bone loss seems to result from other physiological aspects, such as fat and lean mass loss, rather than from gravitational loading decrease.
Review
Food Science & Technology
Mousa Khalafi, Michael E. Symonds, Amir Akbari
Summary: The study compared the effects of exercise training (EX), caloric restriction (CR), and a combination of both on inflammatory markers in overweight and obese individuals. The results indicate that a combination of exercise and caloric restriction may be more effective at reducing inflammatory markers compared to caloric restriction alone in this population.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Endocrinology & Metabolism
Zeinab Yazdanpanah, Sara Beigrezaei, Sahar Mohseni-Takalloo, Sepideh Soltani, Seyede Hamide Rajaie, Tayebeh Zohrabi, Mojtaba Kaviani, Scott C. Forbes, Julien S. Baker, Amin Salehi-Abargouei
Summary: The combination of exercise and weight-loss diets does not significantly impact bone density, but resistance exercise during a low-calorie diet can have a positive effect on bone density. Further clinical trials are needed to confirm these findings.
OSTEOPOROSIS INTERNATIONAL
(2022)
Review
Food Science & Technology
Mousa Khalafi, Karim Azali Alamdari, Michael E. Symonds, Hadi Rohani, Mohammad Hossein Sakhaei
Summary: This study conducted a systematic meta-analysis to compare the effect of exercise training (Ex) combined with dietary interventions (DI) versus DI alone on insulin resistance (IR) and glucose homeostasis. The results showed that Ex + DI had a greater decrease in fasting glucose and IR compared to DI alone, but there was no significant difference in fasting insulin and body weight between the two interventions.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Nutrition & Dietetics
Spyridon Tsirigkakis, George Mastorakos, Yiannis Koutedakis, Vassilis Mougios, Alan M. Nevill, Zoe Pafili, Gregory C. Bogdanis
Summary: A study comparing two high-intensity interval training protocols on obese men showed similar effects in improving regional body composition and fat oxidation. Both training programs effectively reduced trunk fat and increased leg lean mass, while enhancing fat oxidation during exercise. HIIT also resulted in improved peak fat oxidation, VO2peak, and decreased blood lactate levels at submaximal intensities.
Article
Environmental Sciences
Zorimar Rivera-Nunez, Emily S. Barrett, Elizabeth A. Szamreta, Sue A. Shapses, Bo Qin, Yong Lin, Helmut Zarbl, Brian Buckley, Elisa V. Bandera
ENVIRONMENTAL HEALTH
(2019)
Article
Endocrinology & Metabolism
Xiangbing Wang, Zhifeng Sheng, Lingqiong Meng, Chi Su, Stanley Trooskin, Sue A. Shapses
FRONTIERS IN ENDOCRINOLOGY
(2019)
Article
Geriatrics & Gerontology
Monica Castle, Nancy Fiedler, Lilliana Claudia Pop, Stephen J. Schneider, Yvette Schlussel, Deeptha Sukumar, Lihong Hao, Sue A. Shapses
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2020)
Article
Endocrinology & Metabolism
Daniel E. Kammire, Michael P. Walkup, Walter T. Ambrosius, Leon Lenchik, Sue A. Shapses, Barbara J. Nicklas, Denise K. Houston, Anthony P. Marsh, W. Jack Rejeski, Kristen M. Beavers
Article
Medicine, Research & Experimental
Timothy B. Plante, Kelly T. Gleason, Hailey N. Miller, Jeanne Charleston, Kristen McArthur, Cheryl Dennison Himmelfarb, Mariana Lazo, Daniel E. Ford, Edgar R. Miller, Lawrence J. Appel, Stephen P. Juraschek, Nicole Cronin, Scott McClure, Jennifer Miskimon, Christine M. Mitchell, Rita R. Kalyani, David L. Roth, Jennifer A. Schrack, Sarah L. Szanton, Jacek Urbanek, Jeremy Walston, Amal Wanigatunga, Sheriza N. Baksh, Amanda L. Blackford, Shumon Chattopadhyay, Lea T. Drye, John Dodge, Cathleen Ewing, Sana Haider, Stephanie C. Holland, Rosetta Jackson, Andrea Lears, Curtis Meinert, David Shade, Michael Smith, Alice L. Sternberg, James Tonascia, Mark L. Van Natta, Annette Wagoner, Erin D. Michos, J. Denise Bennett, Pamela Bowers, Josef Coresh, Patricia Crowley, Tammy Crunkleton, Briana Dick, Rebecca Evans, Mary Godwin, Lynne Hammann, Deborah Hawks, Karen Horning, Erika Hull, Brandi Mills, Melissa Minotti, Leann Raley, Amanda Reed, Rhonda Reeder, Cassie Reid, Melissa Shuda, Adria Spikes, Rhonda Stouffer, Kelly Weicht, Caroline Abbas, Bernellyn Carey, Syree Davis, Naomi DeRoche-Brown, Debra Gayles, Sherlina Holland, Ina Glenn-Smith, Duane Johnson, Mia Johnson, Eva Keyes, Danielle Santiago, Chanchai Sapun, Valerie Sneed, Lee Swartz, Letitia Thomas, Robert H. Christenson, Show-Hong Duh, Heather Rebuck, Clifford Rosen, Tom Cook, Pamela Duncan, Karen Hansen, Anne Kenny, Sue Shapses, Judy Hannah, Sergei Romashkan, Cindy D. Davis, Christopher T. Sempos, Jack M. Guralnik, J. C. Gallagher
Article
Nutrition & Dietetics
Lihong Hao, Jeffrey L. Carson, Yvette Schlussel, Helaine Noveck, Sue A. Shapses
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2020)
Editorial Material
Nutrition & Dietetics
Sue A. Shapses
JOURNAL OF NUTRITION
(2020)
Article
Biochemistry & Molecular Biology
Lingqiong Meng, Chi Su, Sue A. Shapses, Aseel Al-Dayyeni, Yuling He, Xiangbing Wang
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2020)
Article
Microbiology
J. C. Onishi, M. M. Haggblom, S. A. Shapses
Article
Endocrinology & Metabolism
A. Kreitman, S. H. Schneider, L. Hao, Y. Schlussel, N. T. Bello, S. A. Shapses
Summary: The study found that attenuating postprandial glycemic indices with an alpha-GI significantly decreases postprandial bone resorption, which can be explained by the increase in GLP-1.
OSTEOPOROSIS INTERNATIONAL
(2021)
Article
Nutrition & Dietetics
Connie M. Weaver, Naomi K. Fukagawa, DeAnn Liska, Richard D. Mattes, Gregory Matuszek, Jeri W. Nieves, Sue A. Shapses, Linda G. Snetselaar
Summary: Training in good documentation practices and adherence to regulatory requirements in human nutrition randomized controlled trials has been lacking attention. Gaps exist in clinical nutrition research due to emphasis on drugs and devices, lack of nutrition expertise, and difficulty in distinguishing risks associated with interventions from free-living eating conditions. Controlled-feeding trials provide more experimental control over food consumed, but may lack external validity and pose human behavior issues unrelated to the intervention.
ADVANCES IN NUTRITION
(2021)
Article
Biochemistry & Molecular Biology
A. R. Ogilvie, M. Watford, G. Wu, D. Sukumar, J. Kwon, S. A. Shapses
Summary: A study found that higher protein intake during energy restriction can lead to greater weight loss and a reduction in fasting serum glucogenic amino acids levels, which may have implications for nutrient prioritization during weight loss.
Article
Endocrinology & Metabolism
Anna R. Ogilvie, Yvette Schlussel, Deeptha Sukumar, Lingqiong Meng, Sue A. Shapses
Summary: Increasing protein intake during caloric restriction can improve diet quality and may be another reason for reduced lean body mass, but further study is needed.
Article
Endocrinology & Metabolism
Lingqiong Meng, Xiangbing Wang, Jeffrey L. Carson, Yvette Schlussel, Sue A. Shapses
Summary: This study found that high levels of circulating DBP are associated with better mobility and reduced mortality after hip fracture surgery. DBP may also play a role as an acute phase reactant to tissue injury and clinical outcomes.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Endocrinology & Metabolism
Julia Amariti, Brandon D. McGuire, Anna R. Ogilvie, Kristen M. Beavers, Karen E. Hansen, Yvette Schlussel, Michael P. Walkup, Sue A. Shapses
Summary: Weight loss can lead to a decrease in bone mineral density, especially in the spine, for older women. Vertebral abnormalities may obscure this decline.
CALCIFIED TISSUE INTERNATIONAL
(2022)