Article
Chemistry, Inorganic & Nuclear
Arunachalam Abirami, Umapathy Devan, Rengan Ramesh, Arockiam Antony Joseph Velanganni, Jan Grzegorz Malecki
Summary: This study synthesized six arene ruthenium(ii) complexes and evaluated their inhibitory effects on breast cancer cells. The complexes exhibited good antiproliferative activities by inducing apoptotic cell death through an intrinsic mitochondrial pathway.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Multidisciplinary
Kyo Yamagata, Kento Ueta, Akito Nakai, Atsuhiro Osuka, Takayuki Tanaka
Summary: A recent study has reported that a mu-oxo-bridged dimer of Si(iv) corrole exhibits dual emissive properties depending on the solvent viscosity. In this study, the control of excited-state dynamics and dual emission was examined by introducing meso-aryl substituents. Different structures and emission behaviors were observed in the solid state and excited state, suggesting the importance of molecular structure on the dual emissive properties.
MATERIALS CHEMISTRY FRONTIERS
(2022)
Article
Chemistry, Inorganic & Nuclear
Simon De Kreijger, Benjamin Elias, Ludovic Troian-Gautier
Summary: Two iridium(III) binuclear photosensitizers were investigated for the photooxidation of iodide, bromide, and chloride. The excited states of the photosensitizers were efficiently quenched by the halides, and evidence of reductive excited-state electron transfer was found in solvent mixtures containing water.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Aleksandra Ciesielska, Malgorzata Gawronska, Mariusz Makowski, Sandra Ramotowska
Summary: Two sulfonamide derivatives with different alkylamino substituents (NethylS and NpropylS) were synthesized and extensively studied for their structure and physicochemical properties. The complete spectroscopic and electrochemical profiles of the compounds were determined, along with their assignment of ionic species. The electrochemical characteristics of the sulfonamides were investigated in both aqueous and aprotic solvents using cyclic voltammetry and differential pulse voltammetry. The effect of pH on the redox processes and spectroscopic properties of NethylS/NpropylS was also examined. The activity of the sulfonamide antibiotics was confirmed by forming complexes with d-block metal ions, and the complexing properties and stability constants of NethylS and NpropylS with ruthenium(III) and rhodium(III) ions were determined.
Article
Chemistry, Multidisciplinary
Natacha Cacita, Amanda Batista Silva, Nicolle Azevedo Portela dos Santos, Loyanne Carla Barbosa Ramos, Maria Perpetua Freire de Moraes Del Lama, Rose Mary Zumstein Georgetto Naal, Sofia Nikolaou
Summary: The mu-oxo bridged ruthenium acetate catalyst 1 was characterized by its electronic and infrared spectra, as well as its cyclic voltammograms. The study investigated the biological properties of 1 and its analog 2, including their interaction with proteins and DNA, as well as their potential antiallergic and anticancer activities. The results showed that 1 exhibited antiallergic potential and higher cytotoxicity against cancer cells compared to 2.
Article
Chemistry, Inorganic & Nuclear
Camila Fontes Neves da Silva, Eduardo Tonon de Almeida, Sofia Nikolaou, Anamaria Dias Pereira Alexiou
Summary: This study systematically investigates the thermal decomposition and thermal stability of ten representative triruthenium clusters, showing that their thermal decomposition path and stability depend on the nature of ligands, with the metallic core collapsing upon acetates oxidation in the range from 270 to 300 degrees C.
Article
Chemistry, Inorganic & Nuclear
Urszula K. Komarnicka, Sandra Koziel, Barbara Pucelik, Agata Barzowska, Milosz Siczek, Magdalena Malik, Daria Wojtala, Alessandro Niorettini, Agnieszka Kyziol, Victor Sebastian, Pavel Kopel, Stefano Caramori, Alina Bienko
Summary: Novel heteronuclear Ir-III-Cu-II coordination compounds containing phosphines derived from fluoroquinolones have been synthesized and studied as potential anticancer chemotherapeutics. The compounds were characterized using various analytical techniques and their ability to accumulate in cancer cells and induce cell cycle changes was demonstrated. The study highlights the potential of these compounds as targeted cancer therapies.
INORGANIC CHEMISTRY
(2022)
Article
Multidisciplinary Sciences
Aleksandra Bartkowiak, Oleksandr Korolevych, Blazej Gierczyk, Daniel Pelczarski, Alberto Bossi, Maciej Klein, Lukasz Popenda, Waldemar Stampor, Malgorzata Makowska-Janusik, Maciej Zalas
Summary: The low photon-to-current conversion efficiency is a major limitation of dye-sensitized solar cells. In this study, two new bi-ruthenium sensitizers with extended anchoring ligands were synthesized to investigate the underlying processes determining photovoltaic action mechanisms. Experimental characterization and quantum-chemical calculations were performed to gain insight into the properties of the synthesized molecules. The study highlights the significance of the anchoring group architecture in the molecular design of sensitizers for dye-sensitized solar cell applications.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Inorganic & Nuclear
Christina Georgakopoulou, Dimitrios Thomos, Theodoros Tsolis, Konstantinos Ypsilantis, John C. Plakatouras, Dimitris Kordias, Angeliki Magklara, Constantine Kouderis, Angelos G. Kalampounias, Achilleas Garoufis
Summary: This study synthesized and characterized novel binuclear hexa-arene-ruthenium(II) complexes and investigated their interactions with DNA and cytotoxic activities against cancer cells.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Multidisciplinary
Max Widemann, Sebastian Jeggle, Maximilian Auer, Klaus Eichele, Hartmut Schubert, Christian P. Sindlinger, Lars Wesemann
Summary: Hydridostannylene complexes and related complexes have been successfully synthesized under different reaction conditions, which are of significance for studying transition metal catalyzed reactions.
Article
Chemistry, Inorganic & Nuclear
Weijun Dai, Shiwen Yu, Wen Xu, Ci Kong, Zining Liu, Hongju Yin, Chixian He, Jian-Jun Liu, Feixiang Cheng
Summary: Complexation of nitrogen with pi-conjugated ligands is an effective strategy for synthesizing luminescent molecules. In this study, asymmetric bridging ligands L1 and L2 were designed to successfully synthesize a series of conjugated metal-exchange complexes. These complexes exhibited strong absorption in the visible range and spin-allowed metal-to-ligand charge transfer absorption.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Giulio Bresciani, Stefano Zacchini, Guido Pampaloni, Marco Bortoluzzi, Fabio Marchetti
Summary: A series of novel metal-organic compounds were synthesized by reacting with internal alkynes using a tricarbonyl precursor and catalyst, leading to the formation of unique structures.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Inorganic & Nuclear
Yufang Xie, Qiyi Miao, Wenhao Deng, Yilei Lu, Yinuo Yang, Xiaohui Chen, Rong-Zhen Liao, Shengfa Ye, Chen-Ho Tung, Wenguang Wang
Summary: A diamido-bridged dicobalt complex supported by a diamidonaphthalene ligand, Cp*Co2(2)(mu-1,8-C10H8(NH)(2)) (1), was synthesized and its reactivity towards redox transformations of the Co2N2 core was investigated. It was found that the Co(II)-Co(II) bond can be protonated, resulting in the formation of a bridging hydride [1H](+). The diamidonaphthalene ligand stabilizes the Co(II)Co(III) mixed-valent state (1(+)), which can bind CO to form [1-CO](+). Surprisingly, the mixed-valent complex also activates H2O to give a Co(III)Co(III) hydroxy complex [1-OH](+), accompanied by the release of H2.
INORGANIC CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Priyanka Khanvilkar, Soumya R. Dash, Alisagar Vohra, Ranjitsinh Devkar, Debjani Chakraborty
Summary: New ferrocenyl substituted thiosemicarbazone ligands and their binuclear ruthenium(II) arene complexes have been synthesized and characterized. The structures were established through DFT calculations, and the interactions of the complexes with DNA and BSA have been studied, showing intercalation binding with DNA and good binding affinity with BSA. In vitro cytotoxicity assays against HeLa cell line demonstrated higher potency and cytotoxicity of the complexes at low concentrations.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2021)
Article
Chemistry, Inorganic & Nuclear
Andrea E. Gallio, Leonardo Brustolin, Nicolo Pettenuzzo, Dolores Fregona
Summary: Binuclear dithiocarbamate complexes of Ru(III) have shown promise as potential metal-based anticancer agents. This study proposes the use of heteroleptic ligands as tunable features to develop improved ruthenium-based antiproliferative agents. The cytotoxic activity of a selection of binuclear heteroleptic Ru(III) compounds towards MDA-MB-231 and PC3 cells was evaluated.
