Process Intensification of the Suzuki-Miyaura Reaction over Sol-Gel Entrapped Catalyst SiliaCat DPP-Pd Under Conditions of Continuous Flow

We report the newly developed conditions for the process intensification of the SuzukiMiyaura reaction under flow over solgel entrapped SiliaCat DPP-Pd catalyst with the aim of practical applications. Considerably more concentrated solutions (0.51.0 M) are applied, and flow rate is increased up to the practically relevant 1.0 mL/min threshold. Results indicate complete coupling conversion of several different aryl halides and provide important information of general validity of vital importance for successful process intensification.