Review
Chemistry, Multidisciplinary
Atif Mustafa, Shaheen Siddiqui, Mohd Umar Khan, Abdulaziz Abdullah Qasem Ali, Zeba N. Siddiqui
Summary: The pyrazole moiety is an important structural unit in various pharmacologically and agrochemically significant compounds. Pyrazole-based drugs have demonstrated pharmacological importance in activities such as anti-inflammatory, anti-obesity, and analgesic effects. Various synthetic methodologies have been developed to take advantage of the benefits of pyrazole-based compounds, including heterogeneous catalysis with silica functionalized catalysts garnering interest.
Review
Food Science & Technology
Danfeng Li, Lizhen Hou, Yaxin Gao, Zhiliang Tian, Bei Fan, Fengzhong Wang, Shuying Li
Summary: This article provides a comprehensive overview of the production, biosynthetic pathway, and metabolic regulation of gamma-PGA. By studying the factors that influence its synthesis, it is possible to improve the yield and productivity of γ-PGA and promote its industrial application.
Review
Chemistry, Multidisciplinary
Vipin K. Maikhuri, Ashok K. Prasad, Amitabh Jha, Smriti Srivastava
Summary: Quinoxalines, a class of N-heterocycles, serve as versatile building blocks in synthesizing novel heterocyclic scaffolds and are important intermediates in many bioactive compounds. The synthesis of quinoxaline derivatives has been achieved through various synthetic approaches, including transition metal-catalyzed synthesis, which has been summarized in recent progress.
NEW JOURNAL OF CHEMISTRY
(2021)
Review
Microbiology
Zipeng Li, Xiaofei Zhu, Zhengyu Wu, Tao Sun, Yindong Tong
Summary: This review discusses the classification, biosynthetic pathways, and potential applications of cyanotoxins. By examining representative cyanotoxins and their biosynthetic pathways, the review summarizes and compares recent advances in the heterologous biosynthesis of cyanotoxins in vitro and in vivo, and identifies potential applications and solutions to bottlenecks.
Review
Chemistry, Multidisciplinary
S. Narayanan, P. Tamizhdurai, V. L. Mangesh, C. Ragupathi, P. Santhana Krishnan, A. Ramesh
Summary: This review discusses the preparation, properties, and applications of mordenite zeolite, using various unique sources in the synthesis process. Different template methods and expanded applications of mordenite zeolite have been explored to create unique properties and enhance its usability in various fields.
Article
Chemistry, Multidisciplinary
Alison R. Biery, Daniel M. Knauss
Summary: Cationic polyelectrolytes, including diallyldimethylammonium chloride (DADMAC), are important materials with wide-ranging applications. DADMAC stands out as an attractive monomer due to its good chemical stability, facile synthesis, low toxicity, high availability, and low cost. Recent studies have focused on new polymerization techniques and incorporating DADMAC into different copolymers, expanding their properties and potential applications.
MATERIALS TODAY CHEMISTRY
(2022)
Review
Materials Science, Multidisciplinary
Janitha M. Unagolla, Ambalangodage C. Jayasuriya
Summary: Organoids are self-organized 3D structures derived from various cell sources that mimic tissue-specific architecture and function. Advances in stem cell culture and hydrogel-based extracellular matrices have enabled the development of organoids. This review focuses on the bioengineering technologies used to create physiologically relevant organoids, as well as the importance of the stem cell microenvironment. It also discusses the therapeutic applications of selected organoid models in drug discovery and disease modeling.
APPLIED MATERIALS TODAY
(2022)
Review
Chemistry, Organic
Yi Wang, Xiao-Fei Liu, Wei-Min He
Summary: The synthesis of aldehyde compounds under mild conditions enabled by visible light-induced organic reactions is highly attractive in modern chemistry. This review summarizes the recently developed photocatalytic strategies for the installation of the formyl group into various scaffolds, mainly through the key steps of photocatalytic decarboxylation, oxidation coupling with methylamines/hydrolysis, hydrogen atom transfer of 1,3-dioxolane, and direct generation of formyl radicals.
ORGANIC CHEMISTRY FRONTIERS
(2023)
Review
Biotechnology & Applied Microbiology
Xinrui Zhao, Jingwen Zhou, Guocheng Du, Jian Chen
Summary: Biosynthesis of hemoglobin has become an attractive alternative to chemical extraction, with various microorganisms having synthesized several hemoglobins through metabolic engineering and synthetic biology. These novel strategies not only meet increasing demands but also serve as references for producing other heme-binding proteins.
TRENDS IN BIOTECHNOLOGY
(2021)
Review
Polymer Science
Hong Wang, Hongpeng Li, Chee Keong Lee, Noreen Suliani Mat Nanyan, Guan Seng Tay
Summary: This article presents the reaction modes of enzyme-catalyzed polyester synthesis and the mechanism of lipase-catalyzed polymerization. It also discusses the advantages and disadvantages of enzyme-catalyzed polyester synthesis under different solvent systems. Furthermore, it examines the challenges for further industrialization of this method.
Review
Chemistry, Multidisciplinary
Aicha Amira, Zineb Aouf, Hacene K'tir, Yasmine Chemam, Racha Ghodbane, Rachida Zerrouki, Nour-Eddine Aouf
Summary: This review paper explores recent advancements in the synthesis of alpha-Aminophosphonates from January 2010 to December 2020, with a focus on green chemical approaches such as catalysts, ultrasonic, and microwave irradiations. It aims to be a valuable resource for researchers working in this emerging field.
Review
Engineering, Environmental
Seyed Majid Ghoreishian, Kaveh Shariati, Yun Suk Huh, Jochen Lauterbach
Summary: In order to achieve the net-zero carbon emission target in 2050, ammonia is considered as a key energy carrier for the future energy transition. However, the industrial-scale NH3 synthesis process is energy-intensive and releases vast quantities of CO2. Developing efficient catalysts to allow the process to take place under mild reaction conditions is crucial.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Green & Sustainable Science & Technology
Zamin Mamiyev, Narmiyev O. Balayeva
Summary: This paper discusses the properties and applications of lead sulfide (PbS) nanocrystals in nanotechnology. A comprehensive evaluation of the synthesis, structure, electronic, and optical properties is provided, with a focus on recent breakthroughs in doping, ligands, capping, and hybridization. The enhanced performance of PbS nanocrystals in future optoelectronic devices and biological/chemical applications is highlighted.
MATERIALS TODAY SUSTAINABILITY
(2023)
Review
Materials Science, Multidisciplinary
Waqas Ahmad, Ayesha Khan Tareen, Karim Khan, Maaz Khan, Qasim Khan, Zhiming Wang, Muhammad Maqbool
Summary: Low dimensional materials are promising for electronic and optoelectronic devices due to their unique electronic structure and physiochemical properties. Mixed dimensional heterostructures (MDHs) combine different nanomaterials with various dimensionalities, offering great potential for a wide range of applications. Various dimensionalities of MDHs, especially 2D materials, enhance charge carrier mobilities, optical absorption, and response, making them ideal for developing next-generation optoelectronic devices.
APPLIED MATERIALS TODAY
(2023)
Article
Chemistry, Physical
Devaneyan Joseph, Muhammad Aliyu Idris, Jiajia Chen, Sunwoo Lee
Summary: This review summarizes arylsulfonylation methodologies developed in the last 5 years, including direct arylsulfonylation and multicomponent arylsulfonylation. Aryl reagents react with various substrates or sulfur dioxide surrogates to generate arylsulfonyl compounds in both methods.
Review
Chemistry, Multidisciplinary
Santos Fustero, Daniel M. Sedgwick, Raquel Roman, Pablo Barrio
CHEMICAL COMMUNICATIONS
(2018)
Article
Chemistry, Organic
Raquel Roman, Natalia Mateu, Ines Lopez, Mercedes Medio-Simon, Santos Fustero, Pablo Barrio
Article
Chemistry, Organic
Fernando Rabasa-Alcaniz, Maria Sanchez-Rosello, Santos Fustero, Carlos del Pozo
JOURNAL OF ORGANIC CHEMISTRY
(2019)
Article
Chemistry, Organic
Alberto Llobat, Raquel Roman, Natalia Mateu, Daniel M. Sedgwick, Pablo Barrio, Mercedes Medio-Simon, Santos Fustero
Article
Chemistry, Organic
Kazuki Hirano, Takuya Saito, Yamato Fujihira, Daniel M. Sedgwick, Santos Fustero, Norio Shibata
JOURNAL OF ORGANIC CHEMISTRY
(2020)
Review
Chemistry, Organic
Jorge Escorihuela, Daniel M. Sedgwick, Alberto Llobat, Mercedes Medio-Simon, Pablo Barrio, Santos Fustero
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
(2020)
Article
Chemistry, Organic
Alberto Llobat, Jorge Escorihuela, Daniel M. Sedgwick, Miriam Rodenes, Raquel Roman, Vadim A. Soloshonok, Jianlin Han, Mercedes Medio-Simon, Santos Fustero
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2020)
Review
Chemistry, Multidisciplinary
Jianlin Han, Lorand Kiss, Haibo Mei, Attila Mario Remete, Maja Ponikvar-Svet, Daniel Mark Sedgwick, Raquel Roman, Santos Fustero, Hiroki Moriwaki, Vadim A. Soloshonok
Summary: This comprehensive review focuses on the effects of fluoride ions and organofluorine compounds on human health and the environment, as well as related topics including the reasons for the advancement of fluorine-containing pharmaceuticals and agrochemicals, metabolism of fluorinated drugs, withdrawn fluorinated drugs, natural sources of fluorine compounds in the environment, sources of fluoride intake, and biomarkers of fluoride exposure.
Article
Chemistry, Organic
Yamato Fujihira, Kazuki Hirano, Makoto Ono, Hideyuki Mimura, Takumi Kagawa, Daniel M. Sedgwick, Santos Fustero, Norio Shibata
Summary: A simple protocol using potassium bases with triglyme or tetraglyme as solvents can safely yield pentafluoroethylation products. Encapsulation of the K cation by glymes inhibits its contact with reactive anionic pentafluoroethyl counterions, preventing their transformation into explosive tetrafluoroethylene. The generation of sterically demanding K(G3)(2) and K(G4)(2) cations serves as an effective reservoir for unstable pentafluoroethyl anions.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Organic
Alberto Llobat, Jorge Escorihuela, Santos Fustero, Mercedes Medio-Simon
Summary: In this study, homopropargyl amines and chiral homoallenyl amines were successfully synthesized by the addition of propargylmagnesium bromide to fluorinated aromatic sulfinyl imines. The choice of coordinating or noncoordinating solvents was found to have a significant impact on the diastereoselectivity outcomes. DFT calculations were used to rationalize the regio- and diastereoselectivities observed experimentally.
Review
Chemistry, Applied
Shintaro Kawamura, Pablo Barrio, Santos Fustero, Jorge Escorihuela, Jianlin Han, Vadim A. Soloshonok, Mikiko Sodeoka
Summary: The difunctionalizative trifluoromethylation of unsaturated C-C bonds is a highly useful and efficient method for synthesizing trifluoromethyl compounds. This review focuses on reactions that simultaneously form C-heteroatom and C-H bonds, providing useful CF3 group-containing building blocks. The comprehensive survey categorizes reactions into those that are synthetically mature and those with room for further development.
ADVANCED SYNTHESIS & CATALYSIS
(2023)
Article
Chemistry, Multidisciplinary
Jorge Escorihuela, Santos Fustero
Summary: The chemistry of fluorinated compounds has grown significantly in recent decades due to the diverse properties they possess. Among them, fluorinated chiral imines, especially the Ellman's imines, are crucial in the synthesis of enantioenriched carbocycles and heterocycles with exceptional biological and synthetic properties. This personal account highlights the important findings of our research group in the past two decades, focusing on asymmetric tandem reactions, particularly the intramolecular aza-Michael reaction, diversity oriented synthesis, asymmetric tandem reactions involving a p-tolylsulfinyl group, cycloaddition processes, and the use of fluorinated chiral N-sulfinyl imines and their derivatives as starting materials for enyne compounds in Pauson-Khand reactions, [2+2+2]-cycloadditions, and metathesis reactions.
Article
Chemistry, Organic
Alberto Llobat, Jorge Escorihuela, Carmen Ramirez de Arellano, Santos Fustero, Mercedes Medio-Simon
Summary: This study describes the preparation of merged symmetrical tetrahydroisoquinolines with central chirality through a rhodium-catalyzed intramolecular [2 + 2 + 2] cycloaddition. The results demonstrate that linear triynes lacking a 3-atom tether can efficiently undergo cyclisation. Additional substitution at the benzene rings can be achieved by employing substituted triynes at the terminal triple bonds, leading to more complex tetrahydroisoquinolines.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
Article
Chemistry, Organic
Fernando Rabasa-Alcaniz, Daniel Hammerl, Anabet Sanchez-Merino, Tomas Tejero, Pedro Merino, Santos Fustero, Carlos del Pozo
ORGANIC CHEMISTRY FRONTIERS
(2019)
Review
Chemistry, Organic
Haibo Mei, Jiang Liu, Santos Fustero, Raquel Roman, Renzo Ruzziconi, Vadim A. Soloshonok, Jianlin Han
ORGANIC & BIOMOLECULAR CHEMISTRY
(2019)
