期刊
ORGANIC LETTERS
卷 20, 期 20, 页码 6389-6393出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.8b02676
关键词
-
资金
- Russian Foundation of Basic Research [18-33-01100]
Employing DABCO as a substrate, aryl(mesityl)-iodonium triflates are introduced as arylating agents for a tertiary sp(3)-nitrogen. Mild conditions and exceptional selectivity of the aryl group transfer allow unprecedented N-aryl-DABCO salts to be obtained, bearing substituents of different electronic natures. This metal-free methodology has no analogy among known transition-metal-based reactions. The utility of isolated N-aryl-DABCO salts is demonstrated for the preparation of flibanserin.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据