☆ 4.8 Article

Bis(amino)cyclopropenylidene (BAC) Catalyzed Aza-Benzoin Reaction

ORGANIC LETTERS (2014)

期刊

ORGANIC LETTERS

卷 16, 期 20, 页码 5308-5311

出版社

AMER CHEMICAL SOC

DOI: 10.1021/ol5024807

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Chemistry, Organic

资金

Natural Sciences and Engineering Research Council (NSERC) of Canada
Canada Foundation for Innovation (CFI)
University of Saskatchewan

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摘要

A bis(amino)cyclopropenylidene (BAC) catalyzed aza-benzoin reaction between aldehydes and phosphinoyl imines has been developed. The reaction is general with a wide range of aromatic aldehydes and aromatic imines. The reaction displays excellent chemoselectivity favoring aza-benzoin products over homobenzoin products.

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