期刊
ORGANIC LETTERS
卷 16, 期 12, 页码 3360-3363出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol501394k
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-
资金
- National Natural Science Foundation of China [21272183]
- Fund of the Rising Stars of Shanxi Province [2012KJXX-26]
A novel and efficient palladium-catalyzed intramolecular oxidative cyclization of tertiary enamines for the synthesis of 1,3,4-trisubstituted pyrroles and 1,3-disubstituted indoles has been developed. Trifluoroacetic acid plays an important role in the reaction. A series of pyrroles and indoles with substitution patterns that are not easily accessible by traditional routes were synthesized in good yields under mild conditions.
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