期刊
ORGANIC LETTERS
卷 15, 期 13, 页码 3326-3329出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol401362k
关键词
-
资金
- National Natural Science Foundation of China [21072170, J1210042]
The copper-catalyzed N-methylation of amides and O-methylation of carboxylic acids by using peroxides as the methylating reagent are described. Various amides and carboxylic acids were methylated affording N-substituted amides and esters. Tentative mechanistic studies suggest that this reaction is likely to involve a radical process.
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