期刊
ORGANIC LETTERS
卷 15, 期 10, 页码 2542-2545出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol4010382
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资金
- Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions [10KJA150049]
- Natural Science Foundation of the Jiangsu Higher Education Institutions [11KJB150014]
- Priority Academic Project Development of the Jiangsu Higher Education Institutions
- Foundation of the Key Laboratory of Organic Synthesis of Jiangsu Province [JSK1210]
A highly efficient, catalyst-free synthesis of polysubstituted pyrroles by means of a novel four-component domino reaction of an arylglyoxal monohydrate, an aniline, a dialkyl but-2-ynedioate, and malononitrile is reported. This transformation proceeded via a 6,6a-dihydrofuro[2,3-b]-pyrrole as the key intermediate.
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