期刊
ORGANIC LETTERS
卷 15, 期 17, 页码 4370-4373出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol401901h
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-
资金
- University of Hong Kong
- Hong Kong Research Grants Council [HKU 706109P, HKU 706112P]
A palladium(II)-catalyzed tandem cyclization reaction involving an intramolecular 1,2-aminoalkylation of N-4,6-dienyl beta-keto amides has been developed. This process provides an efficient method for the rapid assembly of pyrrolizidines starting from linear substrates in moderate to good yields and high to excellent diastereoselectivities.
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