☆ 4.8 Article

Synthesis of Novel Aryl and Heteroaryl Acyl Sulfonimidamides via Pd-Catalyzed Carbonylation Using a Nongaseous Precursor

ORGANIC LETTERS (2013)

期刊

ORGANIC LETTERS

卷 15, 期 5, 页码 1056-1059

出版社

AMER CHEMICAL SOC

DOI: 10.1021/ol400049m

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Chemistry, Organic

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Erasmus-Mumdus EXPERTS Foundation

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Reagent

摘要

Hitherto unexplored aryl and heteroaryl acyl sulfonimidamides have been prepared through the development of a new Pd-catalyzed carbonylation protocol. This novel methodology, employing sulfonimidamides as nucleophiles and CO gas ex situ released from solid Mo(CO)(6) in a sealed two-chamber system, yields a wide range of carbamate protected acyl sulfonimidamides in good to excellent yields.

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