期刊
ORGANIC LETTERS
卷 15, 期 24, 页码 6162-6165出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol403019c
关键词
-
资金
- European Research Council under the European Community [227763]
- Fonds der Chemischen Industrie
A general method for the synthesis of 2,4,5-trisubstituted oxazoles has been developed. Starting from commercially available oxazole, successive metalations using TMPMgCl center dot LiCl or TMPZnCl center dot LiCl led to the corresponding magnesiated or zincated species which were stable toward ring fragmentation. Furthermore, they readily reacted with various electrophiles, such as aryl and allylic halides, acid chlorides, TMSCl, and TMS-CN, providing highly functionalized oxazoles.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据