期刊
ORGANIC LETTERS
卷 14, 期 9, 页码 2296-2299出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol300718x
关键词
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资金
- MEXT [2105, 22106518]
- JSPS [22350087]
- Grants-in-Aid for Scientific Research [22350087, 24106717, 22106518] Funding Source: KAKEN
A novel palladium- and copper-catalyzed one-pot multicomponent synthesis of hetero alpha,alpha'-dimers of heterocycles via Sonogashira coupling and double cyclization cascade involving imine formation has been developed. This reaction cascade proceeded under mild conditions, providing a powerful synthetic tool for the assembly of pi-conjugated systems with a combination of palladium-catalyzed post-direct C-H bond arylations.
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