期刊
ORGANIC LETTERS
卷 14, 期 10, 页码 2516-2519出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol300800r
关键词
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资金
- National Institutes of Health [GM-073855, GM-099920]
- AstraZeneca
- NIST
- ACS
- U.S. NSF
The total synthesis of (+/-)-sorocenol B has been accomplished featuring key steps including silver nanoparticle (AgNP)-catalyzed Diels-Alder cycloaddition and late-stage Pd(II)-catalyzed oxidative cyclization. The synthetic natural product exhibited low micromolar cytotoxic activity against a number of human cancer cell lines.
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