期刊
ORGANIC LETTERS
卷 14, 期 21, 页码 5472-5475出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol302550p
关键词
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资金
- CICYT [CTQ2009-07758]
- Generalitat de Catalunya [2009SGR 1024]
- Institute for Research in Biomedicine Barcelona (IRB Barcelona)
- Barcelona Science Park
To address the existing gap in the current set of acid-labile Cys-protecting groups for the Fmoc/fBu strategy, diverse Fmoc-Cys(PG)-OH derivatives were prepared and incorporated into a model tripeptide to study their stability against TFA. S-Dpm proved to be compatible with the commonly used S-Trt group and was applied for the regioselecive construction of disulfide bonds.
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