期刊
ORGANIC LETTERS
卷 13, 期 8, 页码 2008-2011出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol200405w
关键词
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资金
- National Nature Science Foundation of China [20802016, 21072047]
- Ministry of Education [NCET-09-0122]
- National Students Innovation Experiment Program [101047605]
Purine is utilized as a new directing group for the Pd-catalyzed monoarylation of 6-arylpurines with simple aryl iodides via C H bond activation in good yields, providing a complementary tool for the modification of 6-arylpurines (nucleosides). Most importantly, purine can be used as a building block for nucleoside derivatives, and the use of purine as a directing group helps avoid additional synthetic steps.
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