期刊
ORGANIC LETTERS
卷 13, 期 17, 页码 4652-4655出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol201863b
关键词
-
资金
- NIH [CA 53604]
A convergent synthesis of (+)-SCH 351448 (1), a monosodium salt of a C-2-symmetric macrodiolide, is described. Our approach is based on a [4 + 2] annulation with a chiral allyl silane (anti-5c) to assemble the pyran subunits. Homodimerization was carried out in a stepwise fashion; initial esterification at C29' followed by macrocyclization at C29 afforded the desired macrodiolide.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据