Article
Chemistry, Multidisciplinary
Sachin D. Padghan, Li-Ching Wang, Wei-Chi Lin, Jiun-Wei Hu, Wen-Ching Liu, Kew-Yu Chen
Summary: A chemodosimeter with aggregation-induced emission (AIE) characteristic was designed for ultrasensitive and selective sensing of cyanide in a wide pH range of 3.0-12.0. The sensor enables colorimetric and ratiometric fluorescent detection of cyanide in a 90% aqueous solution, and can be conveniently used for cyanide sensing by the naked eye. Additionally, the chemodosimeter was successfully used for sensing cyanide in real environmental water samples.
Article
Chemistry, Organic
Yu-Qing Zhang, Zhi-Nan Kang, Jing-Jie Ming, Sheng-Nan Suo, Jia-Ling Kang, Hai Xu, Ya-Wen Wang, Yu Peng
Summary: A new fluorescent probe has been developed for relay detection of hypochlorite ions and viscosity.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Organic
Yu-Qing Zhang, Zhi-Nan Kang, Jing-Jie Ming, Sheng-Nan Suo, Jia-Ling Kang, Hai Xu, Ya-Wen Wang, Yu Peng
Summary: A fluorescent probe (SWJT-19) has been designed for the relay detection of hypochlorite ions and viscosity based on the correlation between inflammation, reactive oxygen species, and viscosity. The probe can quickly and selectively detect hypochlorite ions, as well as measure the viscosity of the system effectively. Furthermore, the probe has been successfully applied for sequential detection of hypochlorite ions and viscosity in organisms, as well as imaging in mouse inflammation.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Physical
Fengxia Zhang, Wenyao Dong, Xiangfeng Jia, Tianyi Jiang, Xuemei Li, Yongshan Ma
Summary: A novel fluoride anion colorimetric and ratiometric fluorescent probe AOP was designed, synthesized, and characterized to selectively detect F- with unique absorption and fluorescence changes. The interaction between AOP and F- resulted in red shifts of absorption/emission spectrum and ratio fluorescent response, showing potential applications in the field of fluorescence sensing.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Multidisciplinary
Shuai Yin, Shishen Zhang, Yifeng Han
Summary: In this study, a new fluorescent probe TPE-RhodEA based on through-bond energy transfer (TBET) was developed for fast and selective detection of phosgene. The probe exhibited distinct red fluorescence after reacting with phosgene, and it showed a short response time and low detection limit. Furthermore, test TLC strips loaded with TPE-RhodEA enabled direct visualization and reliable quantitative analysis of phosgene by using a color recognition app on a smartphone.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Simeon Hamukoshi, Neliswa Mama, Stiaan Schoeman, Veikko Uahengo
Summary: Two azo dyes were synthesized and their structures were validated. The dyes showed selectivity for Hg2+ and exhibited visual and fluorescence responses. Both dyes formed complexes with Hg2+ in a 1:1 stoichiometry and had strong associations with the metal ion.
Article
Chemistry, Multidisciplinary
Rima D. Alharthy, Nadeem Ahmed, Saman Mubarak, Muhammad Yaqub, Muhammad Khalid, Iqra Shafiq, Muhammad Adnan Asghar, Ataualpa Albert Carmo Braga, Zahid Shafiq
Summary: A series of sensors, SM-1 to SM-3, were designed and synthesized using indole carboxaldehydes and 2,4-dinitrophenyl hydrazine. The synthesis was accompanied by a density functional theory investigation, which revealed a reduction in band gap, a bathochromic shift, and charge transference. SM-3 displayed high selectivity toward F- ions, with a low detection limit and a binding constant of 7.7 x 105.
Article
Chemistry, Multidisciplinary
Rima D. Alharthy, Nadeem Ahmed, Saman Mubarak, Muhammad Yaqub, Muhammad Khalid, Iqra Shafiq, Muhammad Adnan Asghar, Ataualpa Albert Carmo Braga, Zahid Shafiq
Summary: A new series of sensors (SM-1 to SM-3) were synthesized using indole carboxaldehydes and 2,4-dinitrophenyl hydrazine. The deprotonated chromophores exhibited a smaller band gap and a red shift compared to the neutral sensors. Charge transfer from indole to dinitrophenyl hydrazine was observed. Sensor SM-3 showed high selectivity for F- ions, while SM-1 and SM-2 responded to both F- and CN- ions.
Review
Chemistry, Inorganic & Nuclear
Daniel A. McNaughton, Mohamed Fares, Giacomo Picci, Philip A. Gale, Claudia Caltagirone
Summary: This review presents recent developments in fluorescent and colorimetric anion sensors, utilizing various non-covalent interactions and advancements in anion-selective chemodosimeters.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Analytical
Qiaoyin Li, Haiyan Chen, Shumin You, Zhenyu Lin, Zhitao Chen, Fengping Huang, Bin Qiu
Summary: Proper amount of fluorion is important for human health, but excessive fluorion is harmful. A colorimetric and fluorescence enhanced sensor, using MOF material UiO-66 combined with fluorescent dye FITC, is proposed to detect fluorion with high selectivity. It has a good linear relationship in the range of 2-150 mu M (0.038-2.85 ppm), and has been applied to the detection of actual water samples. Field visual detection of fluoride ion is realized, expanding the application of MOF in fluorescence sensing.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Manoj Vora, Shuvankar Dey, Anita Kongor, Manthan Panchal, Falak Panjwani, Ashukumar Verma, Vinod Jain
Summary: RTOC, a novel rhodamine-tren-appended oxacalix[4]arene architecture, has been introduced as a dual-readout sensor for the selective recognition of mercury (Hg2+) and sulphide (S2-) ions, showing high sensitivity. The probe exhibits significant color change and 'turn-on' fluorescence response upon interaction with Hg2+ ions, with a lower limit of detection of 20.5 nM. Additionally, the system is capable of sensing sulphide (S2-) anions in submicromolar range.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Applied
Bin Zuo, Lian Liu, Xicheng Feng, Denghui Li, Wanfang Li, Mingxian Huang, Qinyue Deng
Summary: A novel fluorescent sensor based on triphenylamine was designed for the sensitive detection of trace cyanide anions, featuring a low detection limit and excellent anti-interference performance, suitable for a wide range of pH values.
Article
Chemistry, Analytical
Wenzhu Yin, Hongjin Wang, Bihua Deng, Fang Ma, Jinqiu Zhang, Mingxu Zhou, Haiyang Wang, Yu Lu
Summary: A new pyrylium salt-based fluorescent probe MTPY has been developed as a rapid, highly sensitive, and selective sensor for methylamine vapour, showing a high linear relationship and low detection limit.
Article
Spectroscopy
Bhaswati Devi, Ankur Kanti Guha, Arundhuti Devi
Summary: This study focuses on a newly developed colorimetric Schiff base fluorescent sensor that can detect fluoride ions in an aqueous environment and exhibits a turn-off response. The confirmation of the recognition event is achieved through fluorescence titration, absorbance titration, and Density Functional Theory (DFT) calculation study. The results show that the sensor has a low detection limit for fluoride ions and moderate affinity, making it a promising candidate for monitoring fluoride ions in drinking water.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Chemistry, Analytical
Muhammad Tahir Waseem, Hafiz Muhammad Junaid, Shumaila Majeed, Asad Muhammad Khan, Tariq Mahmood, Sohail Anjum Shahzad
Summary: Two fluorene-based chemosensors 1 and 2 were developed through the Suzuki-Miyaura coupling reaction for sensitive detection of cyanide ions, showing excellent linear response in the Benesi-Hildebrand plot for selective detection of cyanide.
MICROCHEMICAL JOURNAL
(2022)
Article
Biochemistry & Molecular Biology
Xin Guo, Chang-Xiang Liu, Yuan Lu, Ya-Wen Wang, Yu Peng
Summary: A novel two-site chemodosimeter (SWJT-4) based on fluorescein skeleton was designed and synthesized to detect diethyl chlorophosphate (DCP). It acts as a turn-on fluorescent probe for DCP in aqueous solution, exhibiting good selectivity and obvious color change. The two oxime groups of SWJT-4 initiate different reactions with DCP, forming a cyano group and an isoxazole ring, respectively.
Article
Biochemistry & Molecular Biology
Zhiyuan Zhuang, Zhenbiao Luo, Sichen Yao, Yawen Wang, Yu Peng
Summary: A short synthesis of racemic Sacidumlignan B was achieved for the first time, involving a formal reductive coupling and a subsequent Friedel-Crafts cyclization to construct the dihydronaphthalene skeleton of this natural product.
Article
Biochemistry & Molecular Biology
Chang-Xiang Liu, Shu-Yuan Xiao, Xiu-Lin Gong, Xi Zhu, Ya-Wen Wang, Yu Peng
Summary: A novel near-infrared (NIR) fluorescent probe, SWJT-9, was designed and synthesized for the detection of hypochlorite anion (ClO-), showing excellent NIR fluorescence response with a color change under visible light. SWJT-9 demonstrated high selectivity, low detection limit (24.7 nM), and rapid detection (within 2 minutes) for ClO-. The detection mechanism of SWJT-9 on ClO- was confirmed using H-1 NMR, MS spectrum, and density functional theory (DFT) calculations.
Article
Chemistry, Organic
Yang Zhou, Hai Xu, Qing-Xiu Li, Zong-Rui Hou, Ya-Wen Wang, Yu Peng
Summary: Based on the AIE and TICT mechanisms, a fluorescent probe SWJT-12 was designed for the detection of ClO- by using the C equivalent to N bond as a reactive group. The synthesized probe can react with ClO- in a high aqueous phase, showing a large Stokes shift (144 nm) and low biological toxicity. Its limit of detection was calculated to be 0.28 μM. Furthermore, SWJT-12 was successfully used for ratiometric imaging of the exogenous hypochlorite anion in living cells.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Organic
Lin-Yuan Zhang, Li-Jun Xu, Ya-Wen Wang, Yu Peng
Summary: In this study, a ferrocene derivative was synthesized in a one-step reaction from benzotriazole-1-yl-oxytripyrrolidino-phosphonium hexafluorophosphate and ferrocenecarboxylic acid. The structure of the synthesized compound was determined accurately using H-1 and C-13 NMR, and further confirmed by X-ray diffraction analysis of a single crystal.
Article
Biochemistry & Molecular Biology
Xue-Shuang Yu, Mao-Mei Zhu, Rui Zuo, Yu Peng, Ya-Wen Wang
Summary: A new turn-on probe, SWJT-20, based on isophorone fluorophore was synthesized for the detection of nerve agent mimic diethyl chlorophosphite (DCP). SWJT-20 exhibited rapid response to DCP within 2 s using UV-Vis or fluorescent spectra, accompanied by a noticeable change in solution color under visible or UV light, observable with the naked eye. The detection limit of SWJT-20 for DCP was as low as 8.3 nM, surpassing most reported fluorescent probes for DCP detection. Additionally, SWJT-20 enabled quantitative measurement of DCP through ratio changes in absorption spectra (A(427)/A(645)). Furthermore, facile paper sensors were developed based on SWJT-20, allowing colorimetric/fluorometric responses for visual detection. Notably, this probe also detected DCP vapor through gas diffusion experiments.
Article
Chemistry, Analytical
Wei Du, Xiu-Lin Gong, Yang Tian, Xi Zhu, Yu Peng, Ya-Wen Wang
Summary: In this study, a coumarin derivative, SWJT-14, was synthesized as a fluorescence probe to effectively distinguish Cys, Hcy, and GSH in aqueous solutions. The probe showed a lower detection limit for Cys, Hcy, and GSH compared to biothiols in cells. It reacted with biothiols to generate different products with distinct conjugated structures, and fluorescence and UV-Vis spectra were used for differentiation. The detection mechanism was confirmed by MS. SWJT-14 was successfully utilized in cellular experiments for the detection of both endogenous and exogenous biothiols.
Article
Chemistry, Organic
Hai Xu, Long-Zhou Xu, Rui-Ping Huai, Chen Zhang, Sheng-Nan Suo, Ya-Qian Li, Yu Peng, Ya-Wen Wang
Summary: Inspired by the synthetic method of benzoxazine derivatives and our previous research, a fluorescent probe (SWJT-6) was designed for formaldehyde detection based on the cyclization reaction. The synthetic SWJT-6 showed excellent colorimetric and ratiometric response to formaldehyde, and could be perfectly used as test strips to detect formaldehyde. In addition, SWJT-6 has been successfully applied in bioimaging of intracellular and lysosomal formaldehyde in both HeLa cells and zebrafish.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Organic
Xue-Shuang Yu, Rui Zuo, Ming-Ye Shuai, Xu Feng, Yu Peng, Ya-Wen Wang
Summary: A novel ratiometric and colorimetric probe (SWJT-16) based on the isophorone skeleton was synthesized for the detection of diethyl chlorophosphite (DCP), a mimic of nerve agent. SWJT-16 showed a significant emission shift (??(em) = 174 nm) and a remarkable color change from blue to yellow under visible light upon nucleophilic substitution reaction with DCP in DMF. These changes occurred within 6 seconds, faster than most reported ratiometric fluorescent probes for DCP. Furthermore, SWJT-16 was effectively used to monitor gaseous DCP.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Organic
Min Peng, Quan-Rong Du, Xue Yao, Chun-Ni Li, Yang Tian, Yu Peng, Ya-Wen Wang
Summary: A simple fluorescein derivative was synthesized as a fluorescent probe for detecting malondialdehyde (MDA). The probe achieved ring-opening of fluorescein and formation of a benzohydrazide derivative through a synergistic reaction. It exhibited high sensitivity and selectivity for MDA detection, and could quickly and visually detect MDA within 60 s using UV-vis and fluorescent modes. Moreover, the probe showed excellent performance in imaging MDA in living cells and bacteria.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Organic
Nai-Jie Lin, Huan Wu, Jing Peng, Shu-Han Yang, Rui Tan, Yu Peng, Ya-Wen Wang
Summary: A novel ratiometric probe SWJT-10 based on isophorone derivatives was successfully designed and synthesized for the detection of formaldehyde (FA). This probe exhibited significant ratiometric fluorescence response to FA in aqueous solution, with a blue shift from NIR (680 nm) to yellow light region (600 nm). It showed excellent selectivity, high sensitivity, and rapid response to FA (less than 5 s) due to a new recognition mechanism. Furthermore, SWJT-10 has been successfully applied for monitoring FA in living cells and zebrafish.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Organic
Yu-Qing Zhang, Zhi-Nan Kang, Jing-Jie Ming, Sheng-Nan Suo, Jia-Ling Kang, Hai Xu, Ya-Wen Wang, Yu Peng
Summary: A new fluorescent probe has been developed for relay detection of hypochlorite ions and viscosity.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Hai Xu, Chen Zhang, Yu-Qing Zhang, Sheng-Nan Suo, Ya-Wen Wang, Yu Peng
Summary: A novel red-NIR probe (SWJT-8) has been developed for detecting acrolein using the Michael addition reaction. SWJT-8 exhibits unique advantages such as colorimetric discrimination, high selectivity, and the fastest response. This probe has been successfully applied to detect intracellular acrolein.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Organic
Zhen-Biao Luo, Ya-Wen Wang, Yu Peng
ORGANIC & BIOMOLECULAR CHEMISTRY
(2020)
Article
Chemistry, Multidisciplinary
Bao-Jun Wang, Rui-Juan Liu, Jianguo Fang, Ya-Wen Wang, Yu Peng
CHEMICAL COMMUNICATIONS
(2019)
