期刊
ORGANIC LETTERS
卷 12, 期 16, 页码 3693-3695出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol101555g
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资金
- Sanofi-Aventis
An organo-catalyzed Henry reaction, applied to an alpha-keto ester, has allowed the enantioselective synthesis of SSR 241586, a 2,2-disubstituted morpholine active in the treatment of schizophrenia and irritable bowel syndrome (IBS).
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